Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 65,756 bioRxiv papers from 291,238 authors.
Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry
Sarah L. Elson,
the 23andMe Research Team,
Ellen M. Schmidt,
Johanna R. Foerster,
Gonçalo R Abecasis,
Joshua C. Gray,
Harriet de Wit,
Lea K. Davis,
Abraham A Palmer
Posted 07 Jun 2017
bioRxiv DOI: 10.1101/146936 (published DOI: 10.1038/s41593-017-0032-x)
Posted 07 Jun 2017
Delay discounting (DD), which is the tendency to discount the value of delayed versus current rewards, is elevated in a constellation of diseases and behavioral conditions. We performed a genome-wide association study of DD using 23,127 research participants of European ancestry. The most significantly associated SNP was rs6528024 (P = 2.40 x 10-8), which is located in an intron of the gene GPM6B. We also showed that 12% of the variance in DD was accounted for by genotype, and that the genetic signature of DD overlapped with attention-deficit/hyperactivity disorder, schizophrenia, major depression, smoking, personality, cognition, and body weight.
- Downloaded 1,037 times
- Download rankings, all-time:
- Site-wide: 7,086 out of 65,756
- In genetics: 556 out of 3,720
- Year to date:
- Site-wide: 29,289 out of 65,756
- Since beginning of last month:
- Site-wide: 39,555 out of 65,756
Downloads over time
Distribution of downloads per paper, site-wide
- Top preprints of 2018
- Paper search
- Author leaderboards
- Overall metrics
- The API
- Email newsletter
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!