DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan
By
Jenny van Dongen,
fiona hagenbeek,
Matthew J. Suderman,
Peter Roetman,
Karen Sugden,
Andreas G. Chiocchetti,
Khadeeja Ismail,
Rosa H. Mulder,
Jonathan Hafferty,
Mark J Adams,
Rosie M Walker,
Stewart W Morris,
Jari Lahti,
Leanne K Küpers,
Georgia Escaramis,
Silvia Alemany,
Marc Jan Bonder,
Mandy Meijer,
Hill F. Ip,
Rick Jansen,
Bart M. L. Baselmans,
Priyanka Parmar,
Estelle Lowry,
Fabian Streit,
Lea Sirignano,
Tabea Send,
Josef Frank,
Juulia Jylhävä,
Yunzhang Wang,
Pashupati Prasad Mishra,
Olivier F. Colins,
David Corcoran,
Richie Poulton,
Jonathan Mill,
Eilis Hannon,
Louise Arseneault,
Tellervo Korhonen,
eero vuoksimaa,
Janine Felix,
Marian Bakermans-Kranenburg,
Archie Campbell,
Darina Czamara,
Elisabeth Binder,
Eva Corpeleijn,
Juan R Gonzalez,
Regina Grazuleviciene,
Kristine B. Gutzkow,
Jorunn Evandt,
Marina Vafeiadi,
Marieke Klein,
Dennis van der Meer,
lannie ligthart,
BIOS Consortium,
Cornelis Kluft,
Gareth E. Davies,
Christian Hakulinen,
Liisa Keltikangas-Järvinen,
Barbara Franke,
Christine M. Freitag,
Kerstin Konrad,
Amaia Hervas,
Aranzazu Fernández-Rivas,
Agnes Vetro,
Olli T. Raitakari,
Terho Lehtimäki,
Robert Vermeiren,
Timo Strandberg,
Katri Räikkönen,
Harold Snieder,
Stephanie H. Witt,
Michael Deuschle,
Nancy Pedersen,
Sara Hagg,
Jordi Sunyer,
Lude Franke,
Jaakko Kaprio,
Miina Ollikainen,
Terrie E. Moffitt,
Henning Tiemeier,
Marinus H. van Ijzendoorn,
Caroline Relton,
Martine Vrijheid,
Sylvain Sebert,
Marjo-Riitta Jarvelin,
Avshalom Caspi,
Kathryn Evans,
Andrew M McIntosh,
Meike Bartels,
Dorret Boomsma
Posted 22 Jul 2020
bioRxiv DOI: 10.1101/2020.07.22.215939
DNA methylation profiles of aggressive behavior may capture lifetime cumulative effects of genetic, stochastic, and environmental influences associated with aggression. Here, we report the first large meta analysis of epigenome wide association studies (EWAS) of aggressive behavior (N 15,324 participants). ### Competing Interest Statement The following authors declare a conflict of interest: Barbara Franke received educational speaking fees from Medice. Andrew M. McIntosh has received research support from Eli Lilly, Janssen and The Sackler Trust and speaker fees from Illumina and Janssen. Christine M. Freitag has received funding by the DFG, BMBF, State of Hessen, and the EU. She receives royalties for books on ASD, ADHD, and MDD.
Download data
- Downloaded 251 times
- Download rankings, all-time:
- Site-wide: 95,782
- In genetics: 4,290
- Year to date:
- Site-wide: 66,081
- Since beginning of last month:
- Site-wide: 113,839
Altmetric data
Downloads over time
Distribution of downloads per paper, site-wide
PanLingua
News
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!