The Ceratodon purpureus genome uncovers structurally complex, gene rich sex chromosomes
Sarah B. Carey,
Jerry W Jenkins,
John T. Lovell,
Adam C. Payton,
George P. Tiley,
Kerrie W. Barry,
Christopher A. Saski,
Jordan C McBreen,
Roth E. Conrad,
Leslie M Kollar,
Jacob B. Landis,
J. Gordon Burleigh,
Norman J Wickett,
Matthew G Johnson,
Stefan A. Rensing,
Stuart F. McDaniel
Posted 04 Jul 2020
bioRxiv DOI: 10.1101/2020.07.03.163634
Posted 04 Jul 2020
Non-recombining sex chromosomes, like the mammalian Y, often lose genes and accumulate transposable elements, a process termed degeneration1,2. The correlation between suppressed recombination and degeneration is clear in animal XY systems1,2, but the absence of recombination is confounded with other asymmetries between the X and Y. In contrast, UV sex chromosomes, like those found in bryophytes, experience symmetrical population genetic conditions3,4. Here we test for degeneration in the bryophyte UV sex chromosome system through genomic comparisons with new female and male chromosome-scale reference genomes of the moss Ceratodon purpureus. We show that the moss sex chromosomes evolved over 300 million years ago and expanded via two chromosomal fusions. Although the sex chromosomes show signs of weaker purifying selection than autosomes, we find suppressed recombination alone is insufficient to drive gene loss on sex-specific chromosomes. Instead, the U and V sex chromosomes harbor thousands of broadly-expressed genes, including numerous key regulators of sexual development across land plants.
- Downloaded 976 times
- Download rankings, all-time:
- Site-wide: 25,723
- In evolutionary biology: 1,090
- Year to date:
- Site-wide: 9,122
- Since beginning of last month:
- Site-wide: 4,160
Downloads over time
Distribution of downloads per paper, site-wide
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!