Durable memories and efficient neural coding through mnemonic training using the method of loci
Isabella C Wagner,
Boris N. Konrad,
Posted 30 Apr 2020
bioRxiv DOI: 10.1101/2020.04.29.067561
Posted 30 Apr 2020
Mnemonic techniques, such as the method of loci, can powerfully boost memory. Here, we compared memory athletes ranked among the world's top 50 in memory sports to mnemonics-naive controls. In a second study, participants completed a six-weeks memory training, working memory training, or no intervention. Behaviorally, memory training enhanced durable, longer-lasting memories. fMRI during encoding and recognition revealed task-based activation decreases in lateral prefrontal, as well as in parahippocampal and retrosplenial cortices in both memory athletes and participants after memory training, partly associated with better performance after four months. This was complemented by hippocampal-neocortical coupling during consolidation, which was stronger the more durable memories participants formed. Our findings are the first to demonstrate that mnemonic training boosts durable memory formation via decreased task-based activation and increased consolidation thereafter. This is in line with conceptual accounts of neural efficiency and highlights a complex interplay of neural processes critical for extraordinary memory. ### Competing Interest Statement The authors have declared no competing interest.
- Downloaded 469 times
- Download rankings, all-time:
- Site-wide: 72,235
- In neuroscience: 10,557
- Year to date:
- Site-wide: 62,349
- Since beginning of last month:
- Site-wide: 96,464
Downloads over time
Distribution of downloads per paper, site-wide
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!