Rxivist logo

Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 60,240 bioRxiv papers from 267,843 authors.

Large-scale simultaneous measurement of epitopes and transcriptomes in single cells.

By Marlon Stoeckius, Christoph Hafemeister, William Stephenson, Brian Houck-Loomis, Pratip K Chattopadhyay, Harold Swerdlow, Rahul Satija, Peter Smibert

Posted 02 Mar 2017
bioRxiv DOI: 10.1101/113068 (published DOI: 10.1038/nmeth.4380)

Recent high-throughput single-cell sequencing approaches have been transformative for understanding complex cell populations, but are unable to provide additional phenotypic information, such as protein levels of cell-surface markers. Using oligonucleotide-labeled antibodies, we integrate measurements of cellular proteins and transcriptomes into an efficient, sequencing-based readout of single cells. This method is compatible with existing single-cell sequencing approaches and will readily scale as the throughput of these methods increase.

Download data

  • Downloaded 9,120 times
  • Download rankings, all-time:
    • Site-wide: 125 out of 60,240
    • In genomics: 41 out of 4,181
  • Year to date:
    • Site-wide: 3,568 out of 60,240
  • Since beginning of last month:
    • Site-wide: 12,781 out of 60,240

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide

Sign up for the Rxivist weekly newsletter! (Click here for more details.)