Rxivist logo

An ultrasensitive, rapid, and portable coronavirus SARS-CoV-2 sequence detection method based on CRISPR-Cas12

By Curti Lucia, Pereyra-Bonnet Federico, Gimenez Carla Alejandra

Posted 02 Mar 2020
bioRxiv DOI: 10.1101/2020.02.29.971127

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has received global attention due to the recent outbreak in China. In this work, we report a CRISPR-Cas12 based diagnostic tool to detect synthetic SARS-CoV-2 RNA sequences in a proof-of-principle evaluation. The test proved to be sensitive, rapid, and potentially portable. These key traits of the CRISPR method are critical for virus detection in regions that lack resources to use the currently available methods.

Download data

  • Downloaded 10,134 times
  • Download rankings, all-time:
    • Site-wide: 629 out of 118,598
    • In molecular biology: 12 out of 3,622
  • Year to date:
    • Site-wide: 468 out of 118,598
  • Since beginning of last month:
    • Site-wide: 1,903 out of 118,598

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide


Sign up for the Rxivist weekly newsletter! (Click here for more details.)