A model species for agricultural pest genomics: the genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae)
Sean D. Schoville,
Mei-Ju M. Chen,
Martin N. Andersson,
Joshua B Benoit,
Julia H. Bowsher,
Anna K. Childers,
Elise M. Didion,
Elena N. Elpidina,
Richard A. Gibbs,
Emily C. Jennings,
Jeffery W. Jones,
Sher A. Khan,
Nicholas J. Miller,
Robert F. Mitchell,
Subba Reddy Palli,
Kristen A. Panfilio,
Lindsey C. Perkin,
Monica F. Poelchau,
Joseph P. Rinehart,
Hugh M. Robertson,
Andrew J. Rosendale,
Victor M. Ruiz-Arroyo,
Gregg W. C. Thomas,
Alex S. Torson,
Iris M. Vargas Jentzsch,
Matthew T. Weirauch,
Ashley D. Yates,
George D. Yocum,
Posted 22 Sep 2017
bioRxiv DOI: 10.1101/192641 (published DOI: 10.1038/s41598-018-20154-1)
Posted 22 Sep 2017
The Colorado potato beetle is one of the most challenging agricultural pests to manage. It has shown a spectacular ability to adapt to a variety of solanaceaeous plants and variable climates during its global invasion, and, notably, to rapidly evolve insecticide resistance. To examine evidence of rapid evolutionary change, and to understand the genetic basis of herbivory and insecticide resistance, we tested for structural and functional genomic changes relative to other arthropod species using genome sequencing, transcriptomics, and community annotation. Two factors that might facilitate rapid evolutionary change include transposable elements, which comprise at least 17% of the genome and are rapidly evolving compared to other Coleoptera, and high levels of nucleotide diversity in rapidly growing pest populations. Adaptations to plant feeding are evident in gene expansions and differential expression of digestive enzymes in gut tissues, as well as expansions of gustatory receptors for bitter tasting. Surprisingly, the suite of genes involved in insecticide resistance is similar to other beetles. Finally, duplications in the RNAi pathway might explain why Leptinotarsa decemlineata has high sensitivity to dsRNA. The L. decemlineata genome provides opportunities to investigate a broad range of phenotypes and to develop sustainable methods to control this widely successful pest.
- Downloaded 843 times
- Download rankings, all-time:
- Site-wide: 17,586 out of 101,247
- In genomics: 2,166 out of 6,274
- Year to date:
- Site-wide: 45,586 out of 101,247
- Since beginning of last month:
- Site-wide: 40,021 out of 101,247
Downloads over time
Distribution of downloads per paper, site-wide
- 20 Oct 2020: Support for sorting preprints using Twitter activity has been removed, at least temporarily, until a new source of social media activity data becomes available.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!