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Do count-based differential expression methods perform poorly when genes are expressed in only one condition?

By Xiaobei Zhou, Mark D Robinson

Posted 07 Apr 2015
bioRxiv DOI: 10.1101/017673 (published DOI: 10.1186/s13059-015-0781-3)

A correspondence with respect to: Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data Rapaport F, Khanin R, Liang Y, Pirun M, Krek A, Zumbo P, Mason CE, Socci ND and Betel D, Genome Biol 2013, 14:R95

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