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Population-based neuroimaging reveals traces of childbirth in the maternal brain

By Ann-Marie G de Lange, Tobias Kaufmann, Dennis van der Meer, Luigi Maglanoc, Dag Alnaes, Torgeir Moberget, Gwenaƫlle Douaud, Ole A. Andreassen, Lars T. Westlye

Posted 27 May 2019
bioRxiv DOI: 10.1101/650952 (published DOI: 10.1073/pnas.1910666116)

Pregnancy and childbirth involve maternal brain adaptations that promote attachment to and protection of the newborn. Using brain imaging and machine learning, we provide evidence for a positive relationship between number of childbirths and a 'younger-looking' brain in 12,021 women, which could not be explained by common genetic variation. The findings demonstrate that parity can be linked to brain health later in life.

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