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Toil is portable, open-source workflow software that supports contemporary workflow definition languages and can be used to securely and reproducibly run scientific workflows efficiently at large-scale. To demonstrate Toil, we processed over 20,000 RNA-seq samples to create a consistent meta-analysis of five datasets free of computational batch effects that we make freely available. Nearly all the samples were analysed in under four days using a commercial cloud cluster of 32,000 preemptable cores.

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  • Downloaded 6,214 times
  • Download rankings, all-time:
    • Site-wide: 535 out of 92,062
    • In bioinformatics: 82 out of 8,636
  • Year to date:
    • Site-wide: 10,331 out of 92,062
  • Since beginning of last month:
    • Site-wide: 6,633 out of 92,062

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