Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 70,242 bioRxiv papers from 306,709 authors.
Rapid and efficient analysis of 20,000 RNA-seq samples with Toil
Frank Austin Nothaft,
Alden D. Deran,
W. James Kent,
David A. Patterson,
Anthony D. Joseph,
Posted 07 Jul 2016
bioRxiv DOI: 10.1101/062497 (published DOI: 10.1038/nbt.3772)
Posted 07 Jul 2016
Toil is portable, open-source workflow software that supports contemporary workflow definition languages and can be used to securely and reproducibly run scientific workflows efficiently at large-scale. To demonstrate Toil, we processed over 20,000 RNA-seq samples to create a consistent meta-analysis of five datasets free of computational batch effects that we make freely available. Nearly all the samples were analysed in under four days using a commercial cloud cluster of 32,000 preemptable cores.
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