Rxivist logo

Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 55,321 bioRxiv papers from 255,174 authors.

CRISPR-Cas9 Gene Editing in Lizards Through Microinjection of Unfertilized Oocytes

By Ashley M. Rasys, Sungdae Park, Rebecca E. Ball, Aaron J. Alcala, James D. Lauderdale, Douglas B. Menke

Posted 31 Mar 2019
bioRxiv DOI: 10.1101/591446

CRISPR-cas mediated gene editing has enabled the direct manipulation of gene function in many species. However, the reproductive biology of reptiles presents unique barriers for the use of this technology, and there are currently no reptiles with effective methods for targeted mutagenesis. Here we present a new approach that enables the efficient production of CRISPR-cas induced mutations in Anolis lizards, an important model for studies of reptile evolution and development.

Download data

  • Downloaded 3,270 times
  • Download rankings, all-time:
    • Site-wide: 785 out of 55,321
    • In genetics: 78 out of 3,196
  • Year to date:
    • Site-wide: 75 out of 55,321
  • Since beginning of last month:
    • Site-wide: 6,778 out of 55,321

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide

Sign up for the Rxivist weekly newsletter! (Click here for more details.)