Rxivist logo

Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 57,915 bioRxiv papers from 266,490 authors.

A genetically-encoded toolkit of functionalized nanobodies against fluorescent proteins for visualizing and manipulating intracellular signalling

By David L. Prole, Colin W Taylor

Posted 08 Feb 2019
bioRxiv DOI: 10.1101/544700 (published DOI: 10.1186/s12915-019-0662-4)

Background Intrabodies enable targeting of proteins in live cells, but generating specific intrabodies against the thousands of proteins in a proteome poses a challenge. We leverage the widespread availability of fluorescently labelled proteins to visualize and manipulate intracellular signalling pathways in live cells by using nanobodies targeting fluorescent protein tags.

Download data

  • Downloaded 1,120 times
  • Download rankings, all-time:
    • Site-wide: 5,405 out of 57,915
    • In cell biology: 154 out of 2,749
  • Year to date:
    • Site-wide: 889 out of 57,915
  • Since beginning of last month:
    • Site-wide: 8,809 out of 57,915

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide

Sign up for the Rxivist weekly newsletter! (Click here for more details.)