Chloroplasts navigate towards the pathogen interface to counteract infection by the Irish potato famine pathogen
María Eugenia Segretin,
Lok Him Yuen,
David C. A. Gaboriau,
Alexandre Y Leary,
Andrew D. Ward,
Stanley W. Botchway,
Benji C. Bateman,
Tolga O Bozkurt
Posted 09 Jan 2019
bioRxiv DOI: 10.1101/516443
Posted 09 Jan 2019
Chloroplasts are light harvesting organelles that arose from ancient endosymbiotic cyanobacteria. Upon immune activation, chloroplasts switch off photosynthesis, produce anti-microbial compounds, and develop tubular extensions called stromules. We report that chloroplasts navigate to the pathogen interface to counteract infection by the Irish potato famine pathogen Phytophthora infestans, physically associating with the specialised membrane that engulfs pathogen haustoria. Outer envelope protein, chloroplast unusual positioning1 (CHUP1), anchors chloroplasts to the host-pathogen interface. Stromules are induced during infection in a CHUP1-dependent manner, embracing haustoria and interconnecting chloroplasts, to form dynamic organelle clusters. Infection-triggered reprogramming of chloroplasts relies on surface immune signalling, whereas pathogen effectors subvert these immune pulses. Chloroplast are deployed focally, and coordinate to restrict pathogen entry into plant cells, a process actively countered by parasite effectors.
- Downloaded 2,237 times
- Download rankings, all-time:
- Site-wide: 3,035 out of 89,238
- In plant biology: 34 out of 2,751
- Year to date:
- Site-wide: 6,375 out of 89,238
- Since beginning of last month:
- Site-wide: 16,406 out of 89,238
Downloads over time
Distribution of downloads per paper, site-wide
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!