We present scSVA (single-cell Scalable Visualization and Analytics), a lightweight R package for interactive two- and three-dimensional visualization and exploration of massive single-cell omics data. Building in part of methods originally developed for astronomy datasets, scSVA is memory efficient for more than hundreds of millions of cells, can be run locally or in a cloud, and generates high-quality figures. In particular, we introduce a numerically efficient method for single-cell data embedding in 3D which combines an optimized implementation of diffusion maps with a 3D force-directed layout, enabling generation of 3D data visualizations at the scale of a million cells. To facilitate reproducible research, scSVA supports interactive analytics in a cloud with containerized tools. scSVA is available online at https://github.com/klarman-cell-observatory/scSVA.
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- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!