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Parallel sequencing lives, or what makes large sequencing projects successful

By Javier Quilez, Enrique Vidal, Fran├žois le Dily, Fran├žois Serra, Yasmina Cuartero, Ralph Stadhouders, Thomas Graf, Marc A. Marti-Renom, Miguel Beato, Guillaume J. Filion

Posted 10 May 2017
bioRxiv DOI: 10.1101/136358 (published DOI: 10.1093/gigascience/gix100)

T47D_rep2 and b1913e6c1_51720e9cf were two Hi-C samples. They were born and processed at the same time, yet their fates were very different. The life of b1913e6c1_51720e9cf was simple and fruitful, while that of T47D_rep2 was full of accidents and sorrow. At the heart of these differences lies the fact that b1913e6c1_51720e9cf was born under a lab culture of Documentation, Automation, Traceability, Autonomy and compliance with the FAIR Principles. Their lives are a lesson for those who wish to embark on the journey of managing high throughput sequencing data.

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