Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 59,758 bioRxiv papers from 265,632 authors.
Analysis and comparison of genome editing using CRISPResso2
Matthew C. Canver,
Jason M. Gehrke,
Jonathan Y Hsu,
David R Liu,
J. Keith Joung,
Daniel E. Bauer,
Posted 15 Aug 2018
bioRxiv DOI: 10.1101/392217 (published DOI: 10.1038/s41587-019-0032-3)
Posted 15 Aug 2018
Genome editing technologies are rapidly evolving, and analysis of deep sequencing data from target or off-target regions is necessary for measuring editing efficiency and evaluating safety. However, no software exists to analyze base editors, perform allele-specific quantification or that incorporates biologically-informed and scalable alignment approaches. Here, we present CRISPResso2 to fill this gap and illustrate its functionality by experimentally measuring and analyzing the editing properties of six genome editing agents.
- Downloaded 975 times
- Download rankings, all-time:
- Site-wide: 7,031 out of 59,758
- In bioinformatics: 1,282 out of 6,035
- Year to date:
- Site-wide: 7,845 out of 59,758
- Since beginning of last month:
- Site-wide: 18,587 out of 59,758
Downloads over time
Distribution of downloads per paper, site-wide
- Top preprints of 2018
- Paper search
- Author leaderboards
- Overall metrics
- The API
- Email newsletter
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!