Rxivist logo

Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 66,916 bioRxiv papers from 294,600 authors.

Enhancement of larval immune system traits as a correlated response to selection for rapid development in Drosophila melanogaster

By Punyatirtha Dey, Kanika Mendiratta, Joy Bose, Amitabh Joshi

Posted 18 Oct 2015
bioRxiv DOI: 10.1101/029439 (published DOI: 10.1007/s12041-016-0659-5)

We have shown earlier that the evolution of rapid development is accompanied by a correlated decrease in larval feeding rate and competitive ability in laboratory populations of Drosophila melanogaster (Prasad et al. 2001; Shakarad et al. 2005). Here, we show that our faster developing populations have evolved higher hemocyte density and phenol oxidase activity in the larval hemolymph. The increased hemocyte density could be responsible for the evolution of decreased feeding rate as hemocytes and the cephalopharyngeal musculature share common embryonic precursor cells (Kraajiveld et al. 2001). We also show that the bacterial load in larval food vials of the faster developing populations is substantially higher than in controls. Our results suggest that the evolution of reduced competitive ability in the faster developing populations is probably due to larval feeding rate trading off with enhanced larval immune system function. Enhanced larval immune function, in turn, is most likely selected for due to the role of hemocytes (Lanot et al. 2001, Wood and Jacinto 2007) and phenol oxidase (Pentz et al. 1986) in development, and perhaps also due to inadvertent selection on immune performance resulting from the higher bacterial load faced by larvae in the faster developing populations.

Download data

  • Downloaded 273 times
  • Download rankings, all-time:
    • Site-wide: 38,839 out of 66,973
    • In evolutionary biology: 2,889 out of 4,447
  • Year to date:
    • Site-wide: 63,716 out of 66,973
  • Since beginning of last month:
    • Site-wide: 59,454 out of 66,973

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide

Sign up for the Rxivist weekly newsletter! (Click here for more details.)