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The growing link between systemic environment and brain function opens the possibility that cellular communication and composition in blood are correlated with brain health. We tested this concept in frontotemporal dementia with novel, unbiased tools that measure hundreds of soluble signaling proteins or characterize the vast immune cell repertoire in blood. With these tools we discovered complementary abnormalities indicative of abnormal T cell populations and autoimmunity in frontotemporal dementia.

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  • Downloaded 759 times
  • Download rankings, all-time:
    • Site-wide: 12,682 out of 70,543
    • In neuroscience: 2,073 out of 12,685
  • Year to date:
    • Site-wide: 41,964 out of 70,543
  • Since beginning of last month:
    • Site-wide: 46,344 out of 70,543

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