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Analytical performance of eleven SARS-CoV-2 antigen-detecting rapid tests for Delta variant

By Meriem Bekliz, Kenneth Adea, Manel Essaidi-Laziosi, Camille Escadafal, Jilian A. Sacks, Laurent Kaiser, Isabella Eckerle

Posted 07 Oct 2021
medRxiv DOI: 10.1101/2021.10.06.21264535

Global concerns arose as the emerged and rapidly spreading SARS-CoV-2 Delta variant. To date, few data on routine diagnostic performance for Delta are available. Here, we investigate the analytical performance of eleven commercially available antigen-detecting rapid diagnostic tests (Ag-RDTs) for Delta VOC in comparison with current and earlier VOCs (Alpha, Beta and Gamma) and early pandemic variant using cultured SARS-CoV-2. Comparable sensitivity was observed for Delta for the majority of Ag-RDTs.

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