Rxivist logo

Early warning signals regarding environmental suitability in the Drosophila antenna

By Haoyang Rong, Prithwiraj Das, Adalee Lube, David Yang, Debajit Saha, Yehuda Ben-Shahar, Baranidharan Raman

Posted 07 Jun 2017
bioRxiv DOI: 10.1101/146522

The olfactory system is uniquely positioned to warn an organism of environmental threats. Whether and how it encodes such information is not understood. Here, we examined this issue in the fruit fly Drosophila melanogaster. We found that intensity- dependent repulsion to chemicals safeguarded flies from harmful, high-intensity vapor exposures. To understand how sensory input changed as the odor valence switched from innocuous to threatening, we recorded from olfactory receptor neurons (ORNs) in the fly antenna. Primarily, we observed two response non-linearities: recruitment of non-active ORNs at higher intensities, and abrupt transitions in neural excitability from regular spiking to high-firing oscillatory regime. Although non-linearities observed in any single ORN was not a good indicator, a simple linear combination of firing events from multiple neurons provided robust recognition of threatening/repulsive olfactory stimuli. In sum, our results reveal how information necessary to avoid environmental threats may also be encoded in the insect antenna.

Download data

  • Downloaded 394 times
  • Download rankings, all-time:
    • Site-wide: 67,819
    • In neuroscience: 10,302
  • Year to date:
    • Site-wide: 92,187
  • Since beginning of last month:
    • Site-wide: 81,156

Altmetric data


Downloads over time

Distribution of downloads per paper, site-wide


PanLingua

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News