Variants of concern are overrepresented among post-vaccination breakthrough infections of SARS-CoV-2 in Washington State
Abbye E McEwen,
Steven A. Pergam,
Nandita S Mani,
Allison J Zellikoff,
Vanessa A Makarewicz,
Elizabeth R. Brown,
Shah A Mohamed Bakhash,
Noah R Baker,
Robert J Livingston,
Keith R Jerome,
Posted 25 May 2021
medRxiv DOI: 10.1101/2021.05.23.21257679
Posted 25 May 2021
Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOC) and had a median Ct of 20.2 (IQR=17.1-23.3). When compared to 5174 contemporaneous samples sequenced in our laboratory, VOC were significantly enriched among breakthrough infections (p < .05).
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