Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 57,313 bioRxiv papers from 263,927 authors.
Subject-specificity of the correlation between large-scale structural and functional connectivity
Structural connectivity (SC), the physical pathways connecting regions in the brain, and functional connectivity (FC), the temporal co-activations, are known to be tightly linked. However, the nature of this relationship is still not understood. In the present study, we examined this relation more closely in six separate human neuroimaging datasets with different acquisition and preprocessing methods. We show that using simple linear associations, the relation between an individual's SC and FC is not subject specific for five of the datasets. Subject-specificity of SC/FC fit is achieved only for one of the six datasets, the multi-modal Glasser HCP parcellated dataset. We show that subject specificity of SC/FC correspondence is limited across datasets due to relatively small variability between subjects in the SC compared to the larger variability in FC.
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