Rxivist logo

New York City (NYC) emerged as a coronavirus disease 2019 (COVID-19) epicenter in March 2020, but there is limited information regarding potentially unrecognized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections before the first reported case. We utilized a sample pooling strategy to screen for SARS-CoV-2 RNA in de-identified, respiratory pathogen-negative nasopharyngeal specimens from 3,040 patients across our NYC health system who were evaluated for respiratory symptoms or influenza-like illness during the first 10 weeks of 2020. We obtained complete SARS-CoV-2 genome sequences from samples collected between late February and early March. Additionally, we detected SARS-CoV-2 RNA in pooled specimens collected in the week ending 25 January 2020, indicating that SARS-CoV-2 caused sporadic infections in NYC a full month before the first officially documented case.

Download data

  • Downloaded 9,620 times
  • Download rankings, all-time:
    • Site-wide: 1,017
    • In infectious diseases: 315
  • Year to date:
    • Site-wide: 227
  • Since beginning of last month:
    • Site-wide: 11,878

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide