Low-Cost Differential Pressure Spirometry for Emergency Ventilator Tidal Volume Sensing
COVID-19 has become a significant burden on the healthcare systems in the United States and around the world, with many patients requiring invasive mechanical ventilation (IMV) to survive. Close monitoring of patients is critical, with total volume per breath (tidal volume) being one of the most important data points. However, ventilators are complex and expensive devices, typically in the range of tens of thousands of US dollars, and are challenging to manufacture, typically requiring months. Solutions which could augment the ventilator supply rapidly and at low cost in the United States and elsewhere would be valuable. In this paper, we present a standalone tidal volume measurement system consisting of a D-Lite spirometer, pressure sensor, microcontroller, and tubing with a cost of parts less than $50 USD. We also provide a model to predict the error in tidal volume measurements based on the pressure sensor used and the flow during ventilation. We validate this system and show that the tidal volume accuracy for flows above 10L/min was within 10%. We envision this system being used to increase the ventilator supply in resource-constrained settings.
- Downloaded 547 times
- Download rankings, all-time:
- Site-wide: 55,276
- In respiratory medicine: 114
- Year to date:
- Site-wide: 13,907
- Since beginning of last month:
- Site-wide: 9,348
Downloads over time
Distribution of downloads per paper, site-wide
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!