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A population-based seroprevalence survey of severe acute respiratory syndrome coronavirus 2 infection in Beijing, China

By Xiaoli Wang, Wenjing Gao, Shujuan Cui, Yi Zhang, Ke Zheng, Ji Ke, Jun Lv, Canqing Yu, Dianjianyi Sun, Quanyi Wang, Liming Li

Posted 23 Sep 2020
medRxiv DOI: 10.1101/2020.09.23.20197756

BACKGOUND The spread of Coronavirus Disease 2019 (COVID-19) had been controlled in China. The seroprevalence of COVID-19 in Beijing has not been evaluated. METHODS In April, residents in Beijing were randomly enrolled. Blood samples were collected and antibodies to SARS-CoV-2 were tested by two colloidal gold kits. All colloidal gold positive serums were then tested by Micro-neutralization assay. RESULTS None of 2,184 residents participated was tested positive by micro-neutralization assay. The seroprevalence of COVID-19 in Beijing was estimated < 0.17%. CONCLUSIONS The seroprevalence of COVID-19 was low in April suggesting that community-wide spread was prevented in Beijing.

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