SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19
Elizabeth M Anderson,
Eileen C. Goodwin,
Kevin O McNerney,
Madison E. Weirick,
Marcus J Bolton,
Claudia P Arevalo,
Tomaz B. Manzoni,
Amy E. Baxter,
Kurt P. Andrea,
Jessica H. Lee,
Laura A. Vella,
Sarah E Henrickson,
Rebecca M. Harris,
E John Wherry,
Edward M. Behrens,
David T. Teachey,
Scott E. Hensley
Posted 18 Aug 2020
medRxiv DOI: 10.1101/2020.08.17.20176552
Posted 18 Aug 2020
SARS-CoV-2 antibody responses in children remain poorly characterized. Here, we show that pediatric patients with multisystem inflammatory syndrome in children (MIS-C) possess higher SARS-CoV-2 spike IgG titers compared to those with severe coronavirus disease 2019 (COVID-19), likely reflecting a longer time since onset of infection in MIS-C patients.
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