Rxivist logo

A chemical biology view of bioactive small molecules and a binder-based approach to connect biology to precision medicines

By Stuart L Schreiber

Posted 07 Aug 2018
bioRxiv DOI: 10.1101/386904 (published DOI: 10.1002/ijch.201800113)

Evidence is provided that the discovery of small-molecule binders can yield compounds that alter interactomes, protein modifications, cellular lifetimes, and ultimately the specific functions of proteins relevant to human health. These novel mechanisms of action are needed to accelerate the translation of insights from human biology into medicines.

Download data

  • Downloaded 4,595 times
  • Download rankings, all-time:
    • Site-wide: 873 out of 88,995
    • In biochemistry: 21 out of 2,969
  • Year to date:
    • Site-wide: 12,619 out of 88,995
  • Since beginning of last month:
    • Site-wide: 17,536 out of 88,995

Altmetric data


Downloads over time

Distribution of downloads per paper, site-wide


PanLingua

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News