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The clinical outcomes and effectiveness of mHealth interventions for diabetes and hypertension: a systematic review and meta-analysis

By Yaqian Mao, Wei Lin, Junping Weng, Gang Chen

Posted 23 Feb 2020
medRxiv DOI: 10.1101/2020.02.20.20025635

BackgroundWith the development of technology, mobile health (mHealth) intervention has been proposed as a treatment strategy for chronic diseases that could improve the quality of chronic care and outcomes in some developed countries. However, the effectiveness of mHealth intervention in developing countries is not clear. PurposeA systematic review and meta-analysis was conducted to study the clinical outcomes and effectiveness of mHealth interventions for diabetes and hypertension in countries with different levels of economic development. MethodsPubmed, ResearchGate, Embase and Cochrane documents were searched by computer, and the retrieval period was from 2008 to June 2019. All studies were randomized controlled trials (RCTs) comparing mHealth treatments to other traditional treatments. Meta-analysis was conducted using stata software. Results51 RCTs (N=13,054 participants) were eligible for this systematic review and meta-analysis. Compared with the usual care, the mHealth interventions yielded significant mean differences in clinical outcomes, and had a positive effect on countries at different levels of economic development. It is reassuring that we found mHealth interventions combined with human intelligence could significantly improve clinical outcomes more than mHealth interventions alone [WMD (95%Cl)=-6.75 (-9.98, -3.52)] VS [WMD (95%Cl)=-2.53 (-4.99, -0.07)]. The main secondary outcomes showed that mHealth interventions could also improve quality of life, satisfaction and self-efficacy, etc. ConclusionThis review shown that mHealth interventions as a therapeutic strategy could improve the management of diabetes and hypertension in countries with different levels of economic development. O_TEXTBOXWhat is already known about this subject?O_LIWith the development of technology, mobile health (mHealth) intervention has been proposed as a treatment strategy for chronic diseases that could improve the quality of chronic care in some developed countries. C_LIO_LINowdays, there are many mHealth products on the market, whether these mHealth products can improve the patients clinical results or improve the quality of life are still lack of research. C_LI What are the new findings?O_LImHealth interventions as a therapeutic strategy could improve the management of diabetes and hypertension in countries with different levels of economic development. C_LIO_LImHealth interventions combined with human intelligence could significantly improve clinical outcomes more than mHealth interventions alone. C_LI How might these results change the focus of research or clinical practice?O_LImobile health (mHealth) intervention can as a treatment strategy for chronic diseases, especially in the undeveloped places. C_LIO_LImHealth intervention treatments combined with special staff management (pharmacist, dietitian, specialist nurse and sports trainer) had more effective than mHealth interventions alone. C_LI C_TEXTBOX

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