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The expression of PDCD1 and CD274 in T cells and macrophages correlated positively with COVID-19 severity

By Qianqian Gao, Shang Liu, Renpeng Ding, Huanyi Chen, Xuan Dong, Jiarui Xie, Yijian Li, Lei Chen, Huan Liu, Feng Mu

Posted 18 Nov 2020
bioRxiv DOI: 10.1101/2020.11.17.378992

The immune responses underlying the infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain unclear. To help understand the pathology of coronavirus disease 2019 (COVID-19) pandemics, public data were analyzed and the expression of PDCD1 (encoding PD-1) and CD274 (encoding PD-L1) in T cells and macrophages were identified to correlate positively with COVID-19 severity. ### Competing Interest Statement The authors have declared no competing interest.

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