The genetic structure of the world's first farmers
By
Iosif Lazaridis,
Dani Nadel,
Gary Rollefson,
Deborah C Merrett,
Nadin Rohland,
Swapan Mallick,
Daniel Fernandes,
Mario Novak,
Beatriz Gamarra,
Kendra Sirak,
Sarah Connell,
Kristin Stewardson,
Eadaoin Harney,
Qiaomei Fu,
Gloria Gonzalez-Fortes,
Songül Alpaslan Roodenberg,
György Lengyel,
Fanny Bocquentin,
Boris Gasparian,
Janet M. Monge,
Michael Gregg,
Vered Eshed,
Ahuva-Sivan Mizrahi,
Christopher Meiklejohn,
Fokke Gerritsen,
Luminita Bejenaru,
Matthias Blueher,
Archie Campbell,
Gianpero Cavalleri,
David Comas,
Philippe Froguel,
Edmund Gilbert,
Shona M. Kerr,
Peter Kovacs,
Johannes Krause,
Darren McGettigan,
Michael Merrigan,
D. Andrew Merriwether,
Seamus O’Reilly,
Martin B. Richards,
Ornella Semino,
Michel Shamoon-Pour,
Gheorghe Stefanescu,
Michael Stumvoll,
Anke Tönjes,
Antonio Torroni,
James F Wilson,
Loic Yengo,
Nelli A. Hovhannisyan,
Nick Patterson,
Ron Pinhasi,
David Reich
Posted 16 Jun 2016
bioRxiv DOI: 10.1101/059311
(published DOI: 10.1038/nature19310)
We report genome-wide ancient DNA from 44 ancient Near Easterners ranging in time between ~12,000-1,400 BCE, from Natufian hunter-gatherers to Bronze Age farmers. We show that the earliest populations of the Near East derived around half their ancestry from a 'Basal Eurasian' lineage that had little if any Neanderthal admixture and that separated from other non-African lineages prior to their separation from each other. The first farmers of the southern Levant (Israel and Jordan) and Zagros Mountains (Iran) were strongly genetically differentiated, and each descended from local hunter-gatherers. By the time of the Bronze Age, these two populations and Anatolian-related farmers had mixed with each other and with the hunter-gatherers of Europe to drastically reduce genetic differentiation. The impact of the Near Eastern farmers extended beyond the Near East: farmers related to those of Anatolia spread westward into Europe; farmers related to those of the Levant spread southward into East Africa; farmers related to those from Iran spread northward into the Eurasian steppe; and people related to both the early farmers of Iran and to the pastoralists of the Eurasian steppe spread eastward into South Asia.
Download data
- Downloaded 22,529 times
- Download rankings, all-time:
- Site-wide: 52 out of 83,702
- In genetics: 3 out of 4,398
- Year to date:
- Site-wide: 1,103 out of 83,702
- Since beginning of last month:
- Site-wide: 1,212 out of 83,702
Altmetric data
Downloads over time
Distribution of downloads per paper, site-wide
PanLingua
News
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!