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Author: Brian MacKenna

  • ORCiD: http://orcid.org/0000-0002-3786-9063
  • Most recently observed institution: Bennett Institute for Applied Data Science, Nuffield Department of Primary Care Health Sciences, University of Oxford, OX2 6GG, UK

Rankings

  • All-time downloads: 235,185 (rank: 454 )
  • Categories:
    • cardiovascular medicine: 1,256 (rank: 705 (tie) )
    • epidemiology: 194,549 (rank: 100 )
    • health informatics: 438 (rank: 3,524 (tie) )
    • health systems and quality improvement: 1,941 (rank: 265 (tie) )
    • infectious diseases: 18,117 (rank: 4,448 )
    • primary care research: 1,932 (rank: 103 (tie) )
    • psychiatry and clinical psychology: 173 (rank: 9,169 (tie) )
    • public and global health: 6,798 (rank: 980 (tie) )
    • respiratory medicine: 2,873 (rank: 447 (tie) )

Downloads per author, site-wide

Preprints

Comparative effectiveness of two- and three-dose schedules involving AZD1222 and BNT162b2 in people with kidney disease: a linked OpenSAFELY and UK Renal Registry cohort study

infectious diseases more details view paper

No download data for this paper yet.

OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients.

epidemiology more details view paper
  • Downloaded 164,525 times
  • Download rankings, all-time:
    • Site-wide: 33
    • In epidemiology: 7
  • Year to date:
    • Site-wide: 610
  • Since beginning of last month:
    • Site-wide: 853

Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England

epidemiology more details view paper
  • Downloaded 13,424 times
  • Download rankings, all-time:
    • Site-wide: 928
    • In epidemiology: 136
  • Year to date:
    • Site-wide: 15,754
  • Since beginning of last month:
    • Site-wide: 16,167

Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England

infectious diseases more details view paper
  • Downloaded 11,315 times
  • Download rankings, all-time:
    • Site-wide: 1,167
    • In infectious diseases: 376
  • Year to date:
    • Site-wide: 5,351
  • Since beginning of last month:
    • Site-wide: 22,194

Trends and clinical characteristics of COVID-19 vaccine recipients: a federated analysis of 57.9 million patients primary care records in situ using OpenSAFELY.

public and global health more details view paper
  • Downloaded 6,669 times
  • Download rankings, all-time:
    • Site-wide: 2,313
    • In public and global health: 89
  • Year to date:
    • Site-wide: 3,681
  • Since beginning of last month:
    • Site-wide: 7,351

Sales of over-the-counter products containing codeine in 31 countries, 2013-2019: a retrospective observational study

epidemiology more details view paper
  • Downloaded 5,180 times
  • Download rankings, all-time:
    • Site-wide: 3,256
    • In epidemiology: 507
  • Year to date:
    • Site-wide: 408
  • Since beginning of last month:
    • Site-wide: 203

Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe COVID-19 outcomes in non-hospitalised patients: an observational cohort study using the OpenSAFELY platform

epidemiology more details view paper
  • Downloaded 3,578 times
  • Download rankings, all-time:
    • Site-wide: 5,472
    • In epidemiology: 926
  • Year to date:
    • Site-wide: 496
  • Since beginning of last month:
    • Site-wide: 162

Inhaled corticosteroid use and risk COVID-19 related death among 966,461 patients with COPD or asthma: an OpenSAFELY analysis

respiratory medicine more details view paper
  • Downloaded 2,912 times
  • Download rankings, all-time:
    • Site-wide: 7,409
    • In respiratory medicine: 28
  • Year to date:
    • Site-wide: 64,878
  • Since beginning of last month:
    • Site-wide: 78,133

Ethnic differences in COVID-19 infection, hospitalisation, and mortality: an OpenSAFELY analysis of 17 million adults in England

epidemiology more details view paper
  • Downloaded 2,581 times
  • Download rankings, all-time:
    • Site-wide: 8,857
    • In epidemiology: 725
  • Year to date:
    • Site-wide: 28,829
  • Since beginning of last month:
    • Site-wide: 24,425

Comparative effectiveness of BNT162b2 versus mRNA-1273 boosting in England: a cohort study in OpenSAFELY-TPP

epidemiology more details view paper
  • Downloaded 1,896 times
  • Download rankings, all-time:
    • Site-wide: 14,121
    • In epidemiology: 1,713
  • Year to date:
    • Site-wide: 1,266
  • Since beginning of last month:
    • Site-wide: 1,077

Comparative effectiveness of ChAdOx1 versus BNT162b2 COVID-19 vaccines in Health and Social Care workers in England: a cohort study using OpenSAFELY

epidemiology more details view paper
  • Downloaded 1,877 times
  • Download rankings, all-time:
    • Site-wide: 14,321
    • In epidemiology: 1,044
  • Year to date:
    • Site-wide: 27,106
  • Since beginning of last month:
    • Site-wide: 148,602

Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19: a descriptive cohort study within the OpenSAFELY platform

epidemiology more details view paper
  • Downloaded 1,675 times
  • Download rankings, all-time:
    • Site-wide: 17,045
    • In epidemiology: 1,181
  • Year to date:
    • Site-wide: 10,972
  • Since beginning of last month:
    • Site-wide: 81,048

Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: A cohort study from OpenSAFELY

epidemiology more details view paper
  • Downloaded 1,460 times
  • Download rankings, all-time:
    • Site-wide: 21,226
    • In epidemiology: 1,359
  • Year to date:
    • Site-wide: 6,813
  • Since beginning of last month:
    • Site-wide: 47,163

HIV infection and COVID-19 death: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform

infectious diseases more details view paper
  • Downloaded 1,306 times
  • Download rankings, all-time:
    • Site-wide: 25,363
    • In infectious diseases: 2,603
  • Year to date:
    • Site-wide: 63,608
  • Since beginning of last month:
    • Site-wide: 35,520

OpenSAFELY NHS Service Restoration Observatory 1: describing trends and variation in primary care clinical activity for 23.3 million patients in England during the first wave of COVID-19

health systems and quality improvement more details view paper
  • Downloaded 1,300 times
  • Download rankings, all-time:
    • Site-wide: 25,552
    • In health systems and quality improvement: 43
  • Year to date:
    • Site-wide: 68,585
  • Since beginning of last month:
    • Site-wide: 43,175

Clinical coding of long COVID in English primary care: a federated analysis of 58 million patient records in situ using OpenSAFELY

epidemiology more details view paper
  • Downloaded 1,217 times
  • Download rankings, all-time:
    • Site-wide: 28,298
    • In epidemiology: 1,622
  • Year to date:
    • Site-wide: 55,983
  • Since beginning of last month:
    • Site-wide: 82,779

OpenSAFELY: Do adults prescribed Non-steroidal anti-inflammatory drugs have an increased risk of death from COVID-19?

infectious diseases more details view paper
  • Downloaded 1,143 times
  • Download rankings, all-time:
    • Site-wide: 31,264
    • In infectious diseases: 2,890
  • Year to date:
    • Site-wide: 80,862
  • Since beginning of last month:
    • Site-wide: 38,307

Hydroxychloroquine for prevention of COVID-19 mortality: a population-based cohort study

infectious diseases more details view paper
  • Downloaded 973 times
  • Download rankings, all-time:
    • Site-wide: 40,012
    • In infectious diseases: 3,284
  • Year to date:
    • Site-wide: 133,497
  • Since beginning of last month:
    • Site-wide: 126,084

Trends, variation and clinical characteristics of recipients of antivirals and neutralising monoclonal antibodies for non-hospitalised COVID-19: a descriptive cohort study of 23.4 million people in OpenSAFELY

primary care research more details view paper
  • Downloaded 948 times
  • Download rankings, all-time:
    • Site-wide: 41,663
    • In primary care research: 32
  • Year to date:
    • Site-wide: 3,722
  • Since beginning of last month:
    • Site-wide: 17,892

Waning effectiveness of BNT162b2 and ChAdOx1 COVID-19 vaccines over six months since second dose: a cohort study using linked electronic health records

infectious diseases more details view paper
  • Downloaded 902 times
  • Download rankings, all-time:
    • Site-wide: 44,941
    • In infectious diseases: 3,487
  • Year to date:
    • Site-wide: 4,033
  • Since beginning of last month:
    • Site-wide: 92,670

Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune modifying therapies: a nationwide cohort study in the OpenSAFELY platform

infectious diseases more details view paper
  • Downloaded 800 times
  • Download rankings, all-time:
    • Site-wide: 53,836
    • In infectious diseases: 3,902
  • Year to date:
    • Site-wide: 14,655
  • Since beginning of last month:
    • Site-wide: 81,558

OpenSAFELY: impact of national guidance on switching from warfarin to direct oral anticoagulants (DOACs) in early phase of COVID-19 pandemic in England

cardiovascular medicine more details view paper
  • Downloaded 786 times
  • Download rankings, all-time:
    • Site-wide: 55,331
    • In cardiovascular medicine: 108
  • Year to date:
    • Site-wide: 82,517
  • Since beginning of last month:
    • Site-wide: 110,972

OpenSAFELY: Risks of COVID-19 hospital admission and death for people with learning disabilities - a cohort study.

infectious diseases more details view paper
  • Downloaded 709 times
  • Download rankings, all-time:
    • Site-wide: 64,226
    • In infectious diseases: 4,155
  • Year to date:
    • Site-wide: 42,012
  • Since beginning of last month:
    • Site-wide: 185,965

Trends and variation in unsafe prescribing of methotrexate: a cohort study in English NHS primary care.

health systems and quality improvement more details view paper
  • Downloaded 703 times
  • Download rankings, all-time:
    • Site-wide: 64,995
    • In health systems and quality improvement: 94
  • Year to date:
    • Site-wide: 120,586
  • Since beginning of last month:
    • Site-wide: 88,815

Changes in COVID-19-related mortality across key demographic and clinical subgroups: an observational cohort study using the OpenSAFELY platform on 18 million adults in England

epidemiology more details view paper
  • Downloaded 607 times
  • Download rankings, all-time:
    • Site-wide: 79,084
    • In epidemiology: 6,071
  • Year to date:
    • Site-wide: 7,807
  • Since beginning of last month:
    • Site-wide: 3,609

Association between oral anticoagulants and COVID-19 related outcomes: two cohort studies

epidemiology more details view paper
  • Downloaded 599 times
  • Download rankings, all-time:
    • Site-wide: 80,481
    • In epidemiology: 3,607
  • Year to date:
    • Site-wide: 57,123
  • Since beginning of last month:
    • Site-wide: 149,013

Changes in the rate of cardiometabolic and pulmonary events during the COVID-19 pandemic

epidemiology more details view paper
  • Downloaded 551 times
  • Download rankings, all-time:
    • Site-wide: 89,221
    • In epidemiology: 3,868
  • Year to date:
    • Site-wide: 43,356
  • Since beginning of last month:
    • Site-wide: 149,338

Accident and emergency (AE) attendance in England following infection with SARS-CoV-2 Omicron or Delta

infectious diseases more details view paper
  • Downloaded 526 times
  • Download rankings, all-time:
    • Site-wide: 94,324
    • In infectious diseases: 5,280
  • Year to date:
    • Site-wide: 9,810
  • Since beginning of last month:
    • Site-wide: 77,799

Trends and variation in prescribing of suboptimal statin treatment regimes: a cohort study in English primary care

cardiovascular medicine more details view paper
  • Downloaded 517 times
  • Download rankings, all-time:
    • Site-wide: 96,306
    • In cardiovascular medicine: 211
  • Year to date:
    • Site-wide: 166,157
  • Since beginning of last month:
    • Site-wide: 194,407

Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: cohort study in OpenSAFELY using linked primary care, secondary care and death registration data

infectious diseases more details view paper
  • Downloaded 456 times
  • Download rankings, all-time:
    • Site-wide: 110,478
    • In infectious diseases: 5,814
  • Year to date:
    • Site-wide: 55,888
  • Since beginning of last month:
    • Site-wide: 42,566

Impact Of Electronic Health Record Interface Design On Unsafe Prescribing Of Ciclosporin, Tacrolimus and Diltiazem: A Cohort Study In English NHS Primary Care

health informatics more details view paper
  • Downloaded 455 times
  • Download rankings, all-time:
    • Site-wide: 110,675
    • In health informatics: 475
  • Year to date:
    • Site-wide: 176,787
  • Since beginning of last month:
    • Site-wide: 161,790

Predicting COVID-19 related death using the OpenSAFELY platform

infectious diseases more details view paper
  • Downloaded 454 times
  • Download rankings, all-time:
    • Site-wide: 110,904
    • In infectious diseases: 5,639
  • Year to date:
    • Site-wide: 48,240
  • Since beginning of last month:
    • Site-wide: 185,427

Potentially inappropriate prescribing of DOACs to patients with mechanical heart valves: a federated analysis of 57.9 million patients' primary care records in situ using OpenSAFELY

primary care research more details view paper
  • Downloaded 450 times
  • Download rankings, all-time:
    • Site-wide: 111,949
    • In primary care research: 102
  • Year to date:
    • Site-wide: 71,734
  • Since beginning of last month:
    • Site-wide: 80,726

Effectiveness of BNT162b2 booster doses in England: an observational study in OpenSAFELY-TPP

epidemiology more details view paper
  • Downloaded 432 times
  • Download rankings, all-time:
    • Site-wide: 116,428
    • In epidemiology: 5,429
  • Year to date:
    • Site-wide: 13,717
  • Since beginning of last month:
    • Site-wide: 52,540

The impact of the COVID-19 pandemic on prescribing of pancreatic enzyme replacement therapy for people with unresectable pancreatic cancer in England. A cohort study using OpenSafely-TPP

primary care research more details view paper
  • Downloaded 347 times
  • Download rankings, all-time:
    • Site-wide: 140,425
    • In primary care research: 157
  • Year to date:
    • Site-wide: 19,668
  • Since beginning of last month:
    • Site-wide: 10,281

Recording of 'COVID-19 vaccine declined' among vaccination priority groups: a cohort study on 57.9 million NHS patients' primary care records in situ using OpenSAFELY

public and global health more details view paper
  • Downloaded 318 times
  • Download rankings, all-time:
    • Site-wide: 149,251
    • In public and global health: 2,155
  • Year to date:
    • Site-wide: 98,873
  • Since beginning of last month:
    • Site-wide: 80,788

Changes in English medication safety indicators throughout the COVID-19 pandemic: a federated analysis of 57 million patients' primary care records in situ using OpenSAFELY

primary care research more details view paper
  • Downloaded 270 times
  • Download rankings, all-time:
    • Site-wide: 163,282
    • In primary care research: 142
  • Year to date:
    • Site-wide: 29,088
  • Since beginning of last month:
    • Site-wide: 26,008

OpenSAFELY NHS Service Restoration Observatory 2: changes in primary care activity across six clinical areas during the COVID-19 pandemic

primary care research more details view paper
  • Downloaded 239 times
  • Download rankings, all-time:
    • Site-wide: 172,096
    • In primary care research: 149
  • Year to date:
    • Site-wide: 34,929
  • Since beginning of last month:
    • Site-wide: 26,127

Association between household composition and severe COVID-19 outcomes in older people by ethnicity: an observational cohort study using the OpenSAFELY platform

epidemiology more details view paper
  • Downloaded 221 times
  • Download rankings, all-time:
    • Site-wide: 176,792
    • In epidemiology: 7,112
  • Year to date:
    • Site-wide: 39,123
  • Since beginning of last month:
    • Site-wide: 70,089

A hypothesis-free data science approach to identifying novel patterns of clinical interest in clinicians' treatment preferences: clusters of high Pericyazine and Promazine use in England

psychiatry and clinical psychology more details view paper
  • Downloaded 205 times
  • Download rankings, all-time:
    • Site-wide: 180,611
    • In psychiatry and clinical psychology: 1,165
  • Year to date:
    • Site-wide: 43,550
  • Since beginning of last month:
    • Site-wide: 37,082

Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an analysis of 4.3 million adults over the age of 65

epidemiology more details view paper
  • Downloaded 203 times
  • Download rankings, all-time:
    • Site-wide: 181,061
    • In epidemiology: 7,193
  • Year to date:
    • Site-wide: 125,410
  • Since beginning of last month:
    • Site-wide: 128,567

OpenSAFELY: Representativeness of Electronic Health Record platform OpenSAFELY-TPP data compared to the population of England.

primary care research more details view paper
  • Downloaded 166 times
  • Download rankings, all-time:
    • Site-wide: 189,331
    • In primary care research: 163
  • Year to date:
    • Site-wide: 57,772
  • Since beginning of last month:
    • Site-wide: 103,872

Incidence and management of inflammatory arthritis in England before and during the COVID-19 pandemic: a population-level cohort study using OpenSAFELY

rheumatology more details view paper
  • Downloaded 135 times
  • Download rankings, all-time:
    • Site-wide: 195,261
    • In rheumatology: None
  • Year to date:
    • Site-wide: 71,480
  • Since beginning of last month:
    • Site-wide: 26,994

Eleven key measures for monitoring general practice clinical activity during COVID-19 using federated analytics on 48 million adults' primary care records through OpenSAFELY

primary care research more details view paper
  • Downloaded 111 times
  • Download rankings, all-time:
    • Site-wide: 199,169
    • In primary care research: None
  • Year to date:
    • Site-wide: 85,664
  • Since beginning of last month:
    • Site-wide: 4,735

Data-driven identification of unusual prescribing behaviour: an analysis and interactive data tool using six months of primary care data from 6500 practices in England

health informatics more details view paper
  • Downloaded 44 times
  • Download rankings, all-time:
    • Site-wide: 208,748
    • In health informatics: None
  • Year to date:
    • Site-wide: 180,361
  • Since beginning of last month:
    • Site-wide: 64,937

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