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Author: Florian Krammer

Rankings

  • All-time downloads: 521,737 (rank: 52 )
  • Categories:
    • allergy and immunology: 207,583 (rank: 1 )
    • epidemiology: 8,978 (rank: 2,215 (tie) )
    • gastroenterology: 1,790 (rank: 135 (tie) )
    • immunology: 85,444 (rank: 158 )
    • infectious diseases: 172,428 (rank: 212 )
    • microbiology: 23,156 (rank: 960 )
    • obstetrics and gynecology: 536 (rank: 820 (tie) )
    • pediatrics: 2,739 (rank: 285 (tie) )

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Preprints

Evaluation of immunological responses to third COVID-19 vaccine among people treated with sphingosine receptor-1 modulators and anti-CD20 therapy

neurology more details view paper

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Robust spike antibody responses and increased reactogenicity in seropositive individuals after a single dose of SARS-CoV-2 mRNA vaccine

allergy and immunology more details view paper
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A serological assay to detect SARS-CoV-2 seroconversion in humans

allergy and immunology more details view paper
  • Downloaded 96,837 times
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    • Site-wide: 79
    • In allergy and immunology: 2
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    • Site-wide: 1,548
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    • Site-wide: 2,174

Immunological memory to SARS-CoV-2 assessed for up to eight months after infection

immunology more details view paper
  • Downloaded 72,275 times
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    • Site-wide: 119
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    • Site-wide: 1,130
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Humoral immune response and prolonged PCR positivity in a cohort of 1343 SARS-CoV 2 patients in the New York City region

infectious diseases more details view paper
  • Downloaded 36,473 times
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    • Site-wide: 272
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    • Site-wide: 9,589
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SARS-CoV-2 infection induces robust, neutralizing antibody responses that are stable for at least three months

infectious diseases more details view paper
  • Downloaded 18,464 times
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    • Site-wide: 590
    • In infectious diseases: 212
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    • Site-wide: 17,802
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Convalescent plasma treatment of severe COVID-19: A matched control study

infectious diseases more details view paper
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    • Site-wide: 15,005
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Introductions and early spread of SARS-CoV-2 in the New York City area

infectious diseases more details view paper
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    • Site-wide: 707
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    • Site-wide: 6,964
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    • Site-wide: 8,877

Evidence of a significant secretory-IgA-dominant SARS-CoV-2 immune response in human milk following recovery from COVID-19

infectious diseases more details view paper
  • Downloaded 11,760 times
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    • Site-wide: 1,042
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    • Site-wide: 4,818
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Activity of convalescent and vaccine serum against a B.1.1.529 variant SARS-CoV-2 isolate

infectious diseases more details view paper
  • Downloaded 10,871 times
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    • Site-wide: 1,157
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    • Site-wide: 581
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Before the Surge: Molecular Evidence of SARS-CoV-2 in New York City Prior to the First Report

infectious diseases more details view paper
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Seroconversion of a city: Longitudinal monitoring of SARS-CoV-2 seroprevalence in New York City

epidemiology more details view paper
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Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces shedding of SARS-CoV-2 D614G in rhesus macaques

microbiology more details view paper
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Long-lasting neutralizing antibody responses in SARS-CoV-2 seropositive individuals are robustly boosted by immunization with the CoronaVac and BNT162b2 vaccines

infectious diseases more details view paper
  • Downloaded 6,233 times
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    • Site-wide: 2,355
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    • Site-wide: 3,591

The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies that target both the NTD and the RBD

infectious diseases more details view paper
  • Downloaded 5,964 times
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    • Site-wide: 2,492
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    • Site-wide: 4,817

Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled, Phase 1/2 Trial

infectious diseases more details view paper
  • Downloaded 5,216 times
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    • Site-wide: 3,003
    • In infectious diseases: 757
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    • Site-wide: 3,850
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    • Site-wide: 8,042

Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate

microbiology more details view paper
  • Downloaded 5,091 times
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    • Site-wide: 3,112
    • In microbiology: 224
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    • Site-wide: 32,366
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    • Site-wide: 27,123

Mapping SARS-CoV-2 antigenic relationships and serological responses

immunology more details view paper
  • Downloaded 4,645 times
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    • Site-wide: 3,496
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    • Site-wide: 216
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    • Site-wide: 1,005

SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study

infectious diseases more details view paper
  • Downloaded 4,524 times
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    • Site-wide: 3,641
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Safety and immunogenicity of a live recombinant Newcastle disease virus-based COVID-19 vaccine (Patria) administered via the intramuscular or intranasal route: Interim results of a non-randomized open label phase I trial in Mexico

infectious diseases more details view paper
  • Downloaded 3,940 times
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    • Site-wide: 257
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    • Site-wide: 3,097

The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera.

infectious diseases more details view paper
  • Downloaded 3,883 times
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    • Site-wide: 4,482
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  • Year to date:
    • Site-wide: 11,125
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    • Site-wide: 11,213

Efficient mucosal antibody response to SARS-CoV-2 vaccination is induced in previously infected individuals

allergy and immunology more details view paper
  • Downloaded 3,688 times
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Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera

infectious diseases more details view paper
  • Downloaded 3,264 times
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    • Site-wide: 5,770
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    • Site-wide: 18,944
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    • Site-wide: 30,022

Seroprevalence of SARS-CoV-2 among children visiting a hospital during the initial Seattle outbreak

infectious diseases more details view paper
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    • Site-wide: 54,481

mRNA-1273 but not BNT162b2 induces antibodies against polyethylene glycol (PEG) contained in mRNA-based vaccine formulations

allergy and immunology more details view paper
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The inactivated NDV-HXP-S COVID-19 vaccine induces a significantly higher ratio of neutralizing to non-neutralizing antibodies in humans as compared to mRNA vaccines

infectious diseases more details view paper
  • Downloaded 2,823 times
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    • Site-wide: 7,125
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Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

pediatrics more details view paper
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The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera

infectious diseases more details view paper
  • Downloaded 2,779 times
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    • Site-wide: 6,280

Introduction of two prolines and removal of the polybasic cleavage site leads to optimal efficacy of a recombinant spike based SARS-CoV-2 vaccine in the mouse model

microbiology more details view paper
  • Downloaded 2,512 times
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Subtle immunological differences in mRNA-1273 and BNT162b2 COVID-19 vaccine induced Fc-functional profiles

immunology more details view paper
  • Downloaded 2,503 times
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    • Site-wide: 6,013

Antibody Immunological Imprinting on COVID-19 Patients

infectious diseases more details view paper
  • Downloaded 2,463 times
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Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

microbiology more details view paper
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    • Site-wide: 10,185
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Distinct systems serology features in children, elderly and COVID patients

infectious diseases more details view paper
  • Downloaded 2,205 times
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Neutralizing Antibody Responses in COVID-19 Convalescent Sera

infectious diseases more details view paper
  • Downloaded 2,196 times
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    • Site-wide: 10,279
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A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine

microbiology more details view paper
  • Downloaded 2,111 times
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    • Site-wide: 67,848

Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination

immunology more details view paper
  • Downloaded 2,056 times
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A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants

immunology more details view paper
  • Downloaded 1,904 times
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    • Site-wide: 12,766
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    • Site-wide: 43,064

Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19

gastroenterology more details view paper
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A High Through-put Assay for Circulating Antibodies Directed against the S Protein of Severe Acute Respiratory Syndrome Corona virus 2

infectious diseases more details view paper
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SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike

immunology more details view paper
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    • Site-wide: 128,221

Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

microbiology more details view paper
  • Downloaded 1,356 times
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    • Site-wide: 21,374
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    • Site-wide: 50,869

Reduced neutralizing activity of post-SARS-CoV-2 vaccination serum against variants B.1.617.2, B.1.351, B.1.1.7+E484K and a sub-variant of C.37

infectious diseases more details view paper
  • Downloaded 1,337 times
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    • Site-wide: 21,838
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    • Site-wide: 58,271
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    • Site-wide: 73,207

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

microbiology more details view paper
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    • Site-wide: 23,353
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High attack rates of SARS-CoV-2 infection through household-transmission: a prospective study

infectious diseases more details view paper
  • Downloaded 1,233 times
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    • Site-wide: 24,814
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    • Site-wide: 62,757
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    • Site-wide: 90,179

Discovery of a SARS-CoV-2 Broadly-Acting Neutralizing Antibody with Activity against Omicron and Omicron + R346K Variants

microbiology more details view paper
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    • Site-wide: 15,647

The Spike-specific IgA in milk commonly-elicited after SARS-Cov-2 infection is concurrent with a robust secretory antibody response, exhibits neutralization potency strongly correlated with IgA binding, and is highly durable over time

allergy and immunology more details view paper
  • Downloaded 1,164 times
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    • Site-wide: 15,289

Differential T cell reactivity to seasonal coronaviruses and SARS-CoV-2 in community and health care workers

infectious diseases more details view paper
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    • Site-wide: 26,894

Immune response to 2-dose BNT162b2 vaccination and risk of SARS-CoV-2 breakthrough infection: The Shieldvacc-2 study

epidemiology more details view paper
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    • Site-wide: 30,410
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    • Site-wide: 1,515
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    • Site-wide: 5,046

Trivalent NDV-HXP-S vaccine protects against phylogenetically distant SARS-CoV-2 variants of concern in mice

immunology more details view paper
  • Downloaded 954 times
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    • Site-wide: 1,820
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    • Site-wide: 4,933

A public broadly neutralizing antibody class targets a membrane-proximal anchor epitope of influenza virus hemagglutinin

immunology more details view paper
  • Downloaded 890 times
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A Newcastle disease virus-vector expressing a prefusion-stabilized spike protein of SARS-CoV-2 induces protective immune responses against prototype virus and variants of concern in mice and hamsters

immunology more details view paper
  • Downloaded 871 times
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Real Time Investigation of a large Nosocomial Influenza A Outbreak Informed by Genomic Epidemiology

infectious diseases more details view paper
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Murine monoclonal antibodies against RBD of SARS-CoV-2 neutralize authentic wild type SARS-CoV-2 as well as B.1.1.7 and B.1.351 viruses and protect in vivo in a mouse model in a neutralization dependent manner

microbiology more details view paper
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Structure of a germline-like human antibody defines a neutralizing epitope on the SARS-CoV-2 spike NTD

immunology more details view paper
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Seroprevalence of SARS-CoV-2 during pregnancy and associated outcomes: results from an ongoing prospective cohort study, New York City

obstetrics and gynecology more details view paper
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Functionality of the putative surface glycoproteins of the Wuhan spiny eel influenza virus

microbiology more details view paper
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Detection of velogenic avian paramyxoviruses in rock doves in New York City, New York

microbiology more details view paper
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The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization

infectious diseases more details view paper
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Longitudinal analysis of SARS-CoV-2 seroprevalence using multiple serology platforms

infectious diseases more details view paper
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Vaccination with B.1.1.7, B.1.351 and P.1 variants protects mice from challenge with wild type SARS-CoV-2

immunology more details view paper
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Safety and Immunogenicity of An Egg-Based Inactivated Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomized, Placebo-Controlled, Phase 1/2 Trial in Vietnam

infectious diseases more details view paper
  • Downloaded 511 times
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    • Site-wide: 85,533
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    • Site-wide: 47,838

Reduced antibody activity against SARS-CoV-2 B.1.617.2 Delta virus in serum of mRNA-vaccinated patients receiving TNF-alpha inhibitors

infectious diseases more details view paper
  • Downloaded 449 times
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    • Site-wide: 98,801
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    • Site-wide: 88,363

Rapid homogeneous assay for detecting antibodies against SARS-CoV-2

infectious diseases more details view paper
  • Downloaded 371 times
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High Initial Titres of Anti-Spike Antibodies following SARS-CoV-2 Infection is Associated with Faster Decay Rates at Four Months Follow-Up

infectious diseases more details view paper
  • Downloaded 356 times
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SARS-CoV-2 spike-binding antibody longevity and protection from re-infection with antigenically similar SARS-CoV-2 variants

infectious diseases more details view paper
  • Downloaded 345 times
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    • Site-wide: 8,761
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    • Site-wide: 33,199

Monoclonal antibodies targeting the influenza virus N6 neuraminidase

microbiology more details view paper
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The antibody landscapes against Group 1 and 2 influenza virus hemagglutinin following AS03 and MF59 adjuvanted H5N1 vaccination

infectious diseases more details view paper
  • Downloaded 314 times
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Novel epitopes of human monoclonal antibodies targeting the influenza virus N1 neuraminidase

microbiology more details view paper
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