Author: Peter J. Campbell

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Preprints

Pan-cancer analysis of whole genomes

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  • Site-wide: 1,011
  • In cancer biology: 10
• Year to date:
  • Site-wide: 22,427
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  • Site-wide: 22,427

The whole-genome panorama of cancer drivers

• Downloaded 6,548 times
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  • Site-wide: 1,271
  • In cancer biology: 12
• Year to date:
  • Site-wide: 11,104
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  • Site-wide: 11,104

Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

• Downloaded 5,400 times
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  • Site-wide: 1,669
  • In genomics: 164
• Year to date:
  • Site-wide: 18,963
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  • Site-wide: 18,963

Patterns of structural variation in human cancer

• Downloaded 5,323 times
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  • Site-wide: 1,705
  • In cancer biology: 24
• Year to date:
  • Site-wide: 48,460
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  • Site-wide: 48,460

The landscape of somatic mutation in normal colorectal epithelial cells

• Downloaded 3,645 times
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  • Site-wide: 2,916
  • In cancer biology: 42
• Year to date:
  • Site-wide: 15,769
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  • Site-wide: 15,769

Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours

• Downloaded 3,564 times
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  • Site-wide: 3,006
  • In genomics: 354
• Year to date:
  • Site-wide: 22,428
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  • Site-wide: 22,428

Mutational signatures associated with tobacco smoking in human cancer

• Downloaded 3,455 times
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  • Site-wide: 3,156
  • In cancer biology: 50
• Year to date:
  • Site-wide: 98,422
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  • Site-wide: 98,422

Universal Patterns Of Selection In Cancer And Somatic Tissues

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  • Site-wide: 3,325
  • In genomics: 383
• Year to date:
  • Site-wide: 119,862
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  • Site-wide: 119,862

The mutational landscape of normal human endometrial epithelium

• Downloaded 3,075 times
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  • Site-wide: 3,719
  • In cancer biology: 58
• Year to date:
  • Site-wide: 55,589
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  • Site-wide: 55,589

Comprehensive Molecular Characterization of Mitochondrial Genomes in Human Cancers

• Downloaded 2,605 times
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  • Site-wide: 4,721
  • In genomics: 548
• Year to date:
  • Site-wide: 27,352
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  • Site-wide: 27,352

Selective and mechanistic sources of recurrent rearrangements across the cancer genome

• Downloaded 2,334 times
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  • Site-wide: 5,562
  • In cancer biology: 84
• Year to date:
  • Site-wide: 38,655
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  • Site-wide: 38,655

Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

• Downloaded 2,307 times
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  • Site-wide: 5,653
  • In genomics: 659
• Year to date:
  • Site-wide: 26,109
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  • Site-wide: 26,109

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

• Downloaded 2,146 times
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  • Site-wide: 6,256
  • In genomics: 721
• Year to date:
  • Site-wide: 85,127
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  • Site-wide: 85,127

Somatic evolution in non-neoplastic IBD-affected colon

• Downloaded 2,128 times
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  • Site-wide: 6,336
  • In genetics: 314
• Year to date:
  • Site-wide: 14,256
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  • Site-wide: 14,256

Phylogenetic reconstruction of myeloproliferative neoplasm reveals very early origins and lifelong evolution

• Downloaded 1,968 times
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  • Site-wide: 7,090
  • In cancer biology: 118
• Year to date:
  • Site-wide: 1,805
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  • Site-wide: 1,805

Mutational signatures are jointly shaped by DNA damage and repair

• Downloaded 1,958 times
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  • Site-wide: 7,139
  • In genomics: 799
• Year to date:
  • Site-wide: 28,259
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  • Site-wide: 28,259

Personally tailored cancer management based on knowledge banks of genomic and clinical data

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  • Site-wide: 7,460
  • In cancer biology: 128
• Year to date:
  • Site-wide: 86,742
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  • Site-wide: 86,742

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

• Downloaded 1,222 times
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  • Site-wide: 14,498
  • In cancer biology: 312
• Year to date:
  • Site-wide: 67,254
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  • Site-wide: 67,254

Principles governing A-to-I RNA editing in the breast cancer transcriptome

• Downloaded 1,080 times
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  • Site-wide: 17,491
  • In genomics: 1,820
• Year to date:
  • Site-wide: 59,268
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  • Site-wide: 59,268

Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer

• Downloaded 1,021 times
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  • Site-wide: 19,041
  • In cancer biology: 448
• Year to date:
  • Site-wide: 35,219
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  • Site-wide: 35,219

APOBEC3B-dependent kataegis and TREX1-driven chromothripsis in telomere crisis

• Downloaded 1,001 times
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  • Site-wide: 19,609
  • In molecular biology: 532
• Year to date:
  • Site-wide: 28,163
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  • Site-wide: 28,163

Lineage tracing of human embryonic development and foetal haematopoiesis through somatic mutations

• Downloaded 863 times
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  • Site-wide: 24,222
  • In genomics: 2,348
• Year to date:
  • Site-wide: 12,701
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  • Site-wide: 12,701

Elevated somatic mutation burdens in normal human cells due to defective DNA polymerases

• Downloaded 852 times
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  • Site-wide: 24,652
  • In genomics: 2,381
• Year to date:
  • Site-wide: 11,486
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  • Site-wide: 11,486

Multi-site clonality analyses uncovers pervasive subclonal heterogeneity and branching evolution across melanoma metastases

• Downloaded 692 times
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  • Site-wide: 32,921
  • In genomics: 2,926
• Year to date:
  • Site-wide: 58,065
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  • Site-wide: 58,065

Revealing the impact of recurrent and rare structural variants in multiple myeloma

• Downloaded 581 times
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  • Site-wide: 41,267
  • In genomics: 3,423
• Year to date:
  • Site-wide: 25,698
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  • Site-wide: 25,698

Whole genome sequencing provides evidence of two biologically and clinically distinct entities of asymptomatic monoclonal gammopathies: progressive versus stable myeloma precursor condition

• Downloaded 237 times
• Download rankings, all-time:
  • Site-wide: 93,469
  • In cancer biology: 2,836
• Year to date:
  • Site-wide: 52,862
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  • Site-wide: 52,862

Drivers underpinning the malignant transformation of giant cell tumour of bone

• Downloaded 159 times
• Download rankings, all-time:
  • Site-wide: 109,902
  • In genetic and genomic medicine: 462
• Year to date:
  • Site-wide: 59,879
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  • Site-wide: 59,879