Author: Peter J. Campbell

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Preprints

Pan-cancer analysis of whole genomes

• Downloaded 7,994 times
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  • Site-wide: 1,225
  • In cancer biology: 11
• Year to date:
  • Site-wide: 31,860
• Since beginning of last month:
  • Site-wide: 41,190

The whole-genome panorama of cancer drivers

• Downloaded 6,798 times
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  • Site-wide: 1,497
  • In cancer biology: 15
• Year to date:
  • Site-wide: 12,609
• Since beginning of last month:
  • Site-wide: 17,773

Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

• Downloaded 5,597 times
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  • Site-wide: 1,953
  • In genomics: 175
• Year to date:
  • Site-wide: 18,957
• Since beginning of last month:
  • Site-wide: 21,501

Patterns of structural variation in human cancer

• Downloaded 5,438 times
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  • Site-wide: 2,034
  • In cancer biology: 25
• Year to date:
  • Site-wide: 40,493
• Since beginning of last month:
  • Site-wide: 24,948

The landscape of somatic mutation in normal colorectal epithelial cells

• Downloaded 3,938 times
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  • Site-wide: 3,208
  • In cancer biology: 44
• Year to date:
  • Site-wide: 11,720
• Since beginning of last month:
  • Site-wide: 11,887

Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours

• Downloaded 3,659 times
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  • Site-wide: 3,572
  • In genomics: 380
• Year to date:
  • Site-wide: 37,814
• Since beginning of last month:
  • Site-wide: 31,859

Mutational signatures associated with tobacco smoking in human cancer

• Downloaded 3,563 times
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  • Site-wide: 3,702
  • In cancer biology: 50
• Year to date:
  • Site-wide: 47,962
• Since beginning of last month:
  • Site-wide: 65,673

The mutational landscape of normal human endometrial epithelium

• Downloaded 3,418 times
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  • Site-wide: 3,901
  • In cancer biology: 52
• Year to date:
  • Site-wide: 11,783
• Since beginning of last month:
  • Site-wide: 14,858

Universal Patterns Of Selection In Cancer And Somatic Tissues

• Downloaded 3,359 times
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  • Site-wide: 4,014
  • In genomics: 423
• Year to date:
  • Site-wide: 118,838
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  • Site-wide: 103,812

Phylogenetic reconstruction of myeloproliferative neoplasm reveals very early origins and lifelong evolution

• Downloaded 2,856 times
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  • Site-wide: 5,053
  • In cancer biology: 75
• Year to date:
  • Site-wide: 2,003
• Since beginning of last month:
  • Site-wide: 2,022

Spatial genomics maps the structure, character and evolution of cancer clones

• Downloaded 2,730 times
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  • Site-wide: 5,392
  • In cancer biology: 81
• Year to date:
  • Site-wide: 730
• Since beginning of last month:
  • Site-wide: 1,756

Comprehensive Molecular Characterization of Mitochondrial Genomes in Human Cancers

• Downloaded 2,654 times
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  • Site-wide: 5,609
  • In genomics: 600
• Year to date:
  • Site-wide: 60,135
• Since beginning of last month:
  • Site-wide: 85,327

Selective and mechanistic sources of recurrent rearrangements across the cancer genome

• Downloaded 2,412 times
• Download rankings, all-time:
  • Site-wide: 6,473
  • In cancer biology: 100
• Year to date:
  • Site-wide: 51,871
• Since beginning of last month:
  • Site-wide: 50,263

Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

• Downloaded 2,393 times
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  • Site-wide: 6,547
  • In genomics: 707
• Year to date:
  • Site-wide: 42,865
• Since beginning of last month:
  • Site-wide: 52,857

Somatic evolution in non-neoplastic IBD-affected colon

• Downloaded 2,266 times
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  • Site-wide: 7,093
  • In genetics: 321
• Year to date:
  • Site-wide: 24,056
• Since beginning of last month:
  • Site-wide: 29,575

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

• Downloaded 2,181 times
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  • Site-wide: 7,498
  • In genomics: 787
• Year to date:
  • Site-wide: 100,113
• Since beginning of last month:
  • Site-wide: 138,793

Mutational signatures are jointly shaped by DNA damage and repair

• Downloaded 2,002 times
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  • Site-wide: 8,491
  • In genomics: 886
• Year to date:
  • Site-wide: 63,966
• Since beginning of last month:
  • Site-wide: 102,955

Personally tailored cancer management based on knowledge banks of genomic and clinical data

• Downloaded 1,933 times
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  • Site-wide: 8,949
  • In cancer biology: 156
• Year to date:
  • Site-wide: 105,104
• Since beginning of last month:
  • Site-wide: 78,019

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

• Downloaded 1,289 times
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  • Site-wide: 16,367
  • In cancer biology: 354
• Year to date:
  • Site-wide: 65,657
• Since beginning of last month:
  • Site-wide: 117,637

Elevated somatic mutation burdens in normal human cells due to defective DNA polymerases

• Downloaded 1,227 times
• Download rankings, all-time:
  • Site-wide: 17,596
  • In genomics: 1,734
• Year to date:
  • Site-wide: 8,206
• Since beginning of last month:
  • Site-wide: 8,979

Lineage tracing of human embryonic development and foetal haematopoiesis through somatic mutations

• Downloaded 1,223 times
• Download rankings, all-time:
  • Site-wide: 17,673
  • In genomics: 1,742
• Year to date:
  • Site-wide: 8,833
• Since beginning of last month:
  • Site-wide: 14,899

Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer

• Downloaded 1,197 times
• Download rankings, all-time:
  • Site-wide: 18,242
  • In cancer biology: 418
• Year to date:
  • Site-wide: 25,019
• Since beginning of last month:
  • Site-wide: 24,269

Principles governing A-to-I RNA editing in the breast cancer transcriptome

• Downloaded 1,104 times
• Download rankings, all-time:
  • Site-wide: 20,567
  • In genomics: 1,985
• Year to date:
  • Site-wide: 103,666
• Since beginning of last month:
  • Site-wide: 142,431

APOBEC3B-dependent kataegis and TREX1-driven chromothripsis in telomere crisis

• Downloaded 1,064 times
• Download rankings, all-time:
  • Site-wide: 21,699
  • In molecular biology: 582
• Year to date:
  • Site-wide: 53,891
• Since beginning of last month:
  • Site-wide: 113,551

Multi-site clonality analyses uncovers pervasive subclonal heterogeneity and branching evolution across melanoma metastases

• Downloaded 745 times
• Download rankings, all-time:
  • Site-wide: 36,028
  • In genomics: 3,041
• Year to date:
  • Site-wide: 73,752
• Since beginning of last month:
  • Site-wide: 87,238

Revealing the impact of recurrent and rare structural variants in multiple myeloma

• Downloaded 675 times
• Download rankings, all-time:
  • Site-wide: 41,102
  • In genomics: 3,354
• Year to date:
  • Site-wide: 40,124
• Since beginning of last month:
  • Site-wide: 48,139

Whole genome sequencing provides evidence of two biologically and clinically distinct entities of asymptomatic monoclonal gammopathies: progressive versus stable myeloma precursor condition

• Downloaded 295 times
• Download rankings, all-time:
  • Site-wide: 96,394
  • In cancer biology: 2,886
• Year to date:
  • Site-wide: 68,396
• Since beginning of last month:
  • Site-wide: 90,977

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

• Downloaded 229 times
• Download rankings, all-time:
  • Site-wide: 111,911
  • In cancer biology: 3,388
• Year to date:
  • Site-wide: 22,380
• Since beginning of last month:
  • Site-wide: 27,809

Drivers underpinning the malignant transformation of giant cell tumour of bone

• Downloaded 185 times
• Download rankings, all-time:
  • Site-wide: 122,654
  • In genetic and genomic medicine: 635
• Year to date:
  • Site-wide: 102,406
• Since beginning of last month:
  • Site-wide: 118,218