Author: Frauke Muecksch

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Preprints

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants

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  • Site-wide: 125
  • In immunology: 5
• Year to date:
  • Site-wide: 626
• Since beginning of last month:
  • Site-wide: 1,810

Evolution of Antibody Immunity to SARS-CoV-2

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  • Site-wide: 307
  • In immunology: 17
• Year to date:
  • Site-wide: 733
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  • Site-wide: 1,070

Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals

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  • Site-wide: 397
  • In immunology: 24
• Year to date:
  • Site-wide: 10,089
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  • Site-wide: 8,075

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

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  • Site-wide: 685
  • In microbiology: 74
• Year to date:
  • Site-wide: 14,920
• Since beginning of last month:
  • Site-wide: 49,786

Anti- SARS-CoV-2 Receptor Binding Domain Antibody Evolution after mRNA Vaccination

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  • Site-wide: 697
  • In immunology: 34
• Year to date:
  • Site-wide: 3,249
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  • Site-wide: 6,077

Longitudinal analysis of clinical serology assay performance and neutralising antibody levels in COVID19 convalescents

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  • Site-wide: 1,208
  • In infectious diseases: 387
• Year to date:
  • Site-wide: 50,655
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  • Site-wide: 33,906

Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine Dose

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  • Site-wide: 1,904
  • In immunology: 70
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  • Site-wide: 169
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  • Site-wide: 11,413

Naturally enhanced neutralizing breadth to SARS-CoV-2 after one year

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  • Site-wide: 1,985
  • In immunology: 77
• Year to date:
  • Site-wide: 7,542
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  • Site-wide: 11,025

Serological Analysis of New York City COVID19 Convalescent Plasma Donors

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  • Site-wide: 2,508
  • In infectious diseases: 673
• Year to date:
  • Site-wide: 26,878
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  • Site-wide: 10,026

Plasma neutralization properties of the SARS-CoV-2 Omicron variant

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  • Site-wide: 2,701
  • In infectious diseases: 708
• Year to date:
  • Site-wide: 1,159
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  • Site-wide: 13,173

Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

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  • Site-wide: 3,458
  • In immunology: 138
• Year to date:
  • Site-wide: 68,408
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  • Site-wide: None

Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies

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  • Site-wide: 3,576
  • In microbiology: 256
• Year to date:
  • Site-wide: 14,116
• Since beginning of last month:
  • Site-wide: 175,136

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

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  • Site-wide: 6,057
  • In microbiology: 394
• Year to date:
  • Site-wide: 45,119
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  • Site-wide: 18,302

Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies

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  • Site-wide: 6,281
  • In microbiology: 399
• Year to date:
  • Site-wide: 18,630
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Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity

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  • Site-wide: 6,285
  • In biochemistry: 114
• Year to date:
  • Site-wide: 15,843
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  • Site-wide: 20,042

Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants

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  • Site-wide: 12,233
  • In immunology: 460
• Year to date:
  • Site-wide: 19,544
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  • Site-wide: 34,842

Enhanced SARS-CoV-2 Neutralization by Secretory IgA in vitro

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  • Site-wide: 12,320
  • In immunology: 463
• Year to date:
  • Site-wide: 45,132
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  • Site-wide: 111,143

Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins

• Downloaded 1,889 times
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  • Site-wide: 13,683
  • In immunology: 519
• Year to date:
  • Site-wide: 1,047
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  • Site-wide: 7,249

Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo

• Downloaded 1,762 times
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  • Site-wide: 15,252
  • In microbiology: 874
• Year to date:
  • Site-wide: 74,444
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  • Site-wide: 50,923

SARS-CoV-2 neutralization after mRNA vaccination and variant breakthrough infection

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  • Site-wide: 18,178
  • In infectious diseases: 2,177
• Year to date:
  • Site-wide: 1,374
• Since beginning of last month:
  • Site-wide: 120,118

Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry

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  • Site-wide: 18,813
  • In microbiology: 1,079
• Year to date:
  • Site-wide: 24,356
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  • Site-wide: 73,307

Longitudinal variation in SARS-CoV-2 antibody levels and emergence of viral variants: implications for the ability of serological assays to predict immunity.

• Downloaded 1,482 times
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  • Site-wide: 19,920
  • In infectious diseases: 2,276
• Year to date:
  • Site-wide: 36,189
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  • Site-wide: 115,869

Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

• Downloaded 952 times
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  • Site-wide: 39,569
  • In immunology: 1,370
• Year to date:
  • Site-wide: 81,055
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  • Site-wide: 34,643

Humoral immunity to SARS-CoV-2 elicited by combination COVID-19 vaccination regimens

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  • Site-wide: 42,899
  • In immunology: 1,608
• Year to date:
  • Site-wide: 3,254
• Since beginning of last month:
  • Site-wide: 9,520

Antibody feedback regulation of memory B cell development in SARS-CoV-2 mRNA vaccination

• Downloaded 842 times
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  • Site-wide: 47,534
  • In allergy and immunology: None
• Year to date:
  • Site-wide: 3,617
• Since beginning of last month:
  • Site-wide: 1,152

A recombinant protein SARS-CoV-2 candidate vaccine elicits high-titer neutralizing antibodies in macaques.

• Downloaded 758 times
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  • Site-wide: 55,523
  • In immunology: 1,816
• Year to date:
  • Site-wide: 117,617
• Since beginning of last month:
  • Site-wide: None

Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape

• Downloaded 663 times
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  • Site-wide: 67,113
  • In microbiology: None
• Year to date:
  • Site-wide: 5,331
• Since beginning of last month:
  • Site-wide: 805

Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine

• Downloaded 479 times
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  • Site-wide: 100,087
  • In immunology: 3,820
• Year to date:
  • Site-wide: 8,997
• Since beginning of last month:
  • Site-wide: 1,796

Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection

• Downloaded 470 times
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  • Site-wide: 102,205
  • In immunology: None
• Year to date:
  • Site-wide: 9,306
• Since beginning of last month:
  • Site-wide: 2,250

Antigen presentation dynamics shape the response to emergent variants like SARS-CoV-2 Omicron strain after multiple vaccinations with wild type strain

• Downloaded 443 times
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  • Site-wide: 108,540
  • In immunology: None
• Year to date:
  • Site-wide: 10,284
• Since beginning of last month:
  • Site-wide: 501

Comparison of SARS-CoV-2 serological assays for use in epidemiological surveillance in Scotland

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  • Site-wide: 130,242
  • In infectious diseases: 6,245
• Year to date:
  • Site-wide: 41,780
• Since beginning of last month:
  • Site-wide: 89,735

Evaluation of SARS-CoV-2 Antibody Point of Care Devices in the Laboratory and Clinical Setting

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  • Site-wide: 146,725
  • In pathology: 812
• Year to date:
  • Site-wide: 44,971
• Since beginning of last month:
  • Site-wide: 92,122