Author: Wei Li

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Preprints

SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19

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  • Site-wide: 1,540
  • In infectious diseases: 455
• Year to date:
  • Site-wide: 24,427
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  • Site-wide: 14,634

Highly ACE2 Expression in Pancreas May Cause Pancreas Damage After SARS-CoV-2 Infection

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  • Site-wide: 1,647
  • In infectious diseases: 489
• Year to date:
  • Site-wide: 25,156
• Since beginning of last month:
  • Site-wide: 23,000

Precautions are Needed for COVID-19 Patients with Coinfection of Common Respiratory Pathogens

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  • Site-wide: 1,890
  • In epidemiology: 234
• Year to date:
  • Site-wide: 13,765
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  • Site-wide: 27,102

Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

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  • Site-wide: 1,994
  • In infectious diseases: 556
• Year to date:
  • Site-wide: 43,104
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  • Site-wide: 33,075

Genomic epidemiology of SARS-CoV-2 in Guangdong Province, China

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  • Site-wide: 2,666
  • In infectious diseases: 711
• Year to date:
  • Site-wide: 1,091
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  • Site-wide: 9,080

Cryo-EM Structures of the N501Y SARS-CoV-2 Spike Protein in Complex with ACE2 and Two Potent Neutralizing Antibodies

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  • Site-wide: 6,573
  • In biophysics: 104
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In Vivo CRISPR Screens Identify E3 Ligase Cop1 as a Modulator of Macrophage Infiltration and Cancer Immunotherapy Target

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  • Site-wide: 9,897
  • In cancer biology: 177
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  • Site-wide: 13,664
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  • Site-wide: 10,981

What is required to prevent a second major outbreak of the novel coronavirus SARS-CoV-2 upon lifting the metropolitan-wide quarantine of Wuhan city, China

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  • Site-wide: 10,880
  • In infectious diseases: 1,596
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  • Site-wide: 98,756
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  • Site-wide: 91,243

A Bacterial Bile Acid Metabolite Modulates Treg Activity through the Nuclear Hormone Receptor NR4A1

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  • Site-wide: 11,206
  • In immunology: 446
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Development and clinical evaluation of non-viral genome specific targeted CAR T cells in relapsed/refractory B-cell non-Hodgkin lymphoma

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  • Site-wide: 18,850
  • In oncology: 26
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  • Site-wide: 32,048
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  • Site-wide: 26,425

Human Identical Sequences of SARS-CoV-2 Promote Clinical Progression of COVID-19 by Upregulating Hyaluronan via NamiRNA-Enhancer Network

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  • Site-wide: 41,554
  • In molecular biology: 1,150
• Year to date:
  • Site-wide: 34,109
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  • Site-wide: 31,773

Dynamic Analysis of Alternative Polyadenylation from Single-Cell RNA-Seq (scDaPars) Reveals Cell Subpopulations Invisible to Gene Expression Analysis

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  • Site-wide: 42,055
  • In bioinformatics: 4,336
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  • Site-wide: 56,261
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  • Site-wide: 66,295

Excessive matrix metalloproteinase-1 and hyperactivation of endothelial cells occurred in COVID-19 patients and were associated with the severity of COVID-19

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  • Site-wide: 52,229
  • In infectious diseases: 3,690
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  • Site-wide: 36,958
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  • Site-wide: 35,463

Chest Computed Tomography for the Diagnosis of Patients with Coronavirus Disease 2019 (COVID-19): A Rapid Review and Meta-Analysis

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  • Site-wide: 55,437
  • In radiology and imaging: 95
• Year to date:
  • Site-wide: 88,680
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  • Site-wide: 142,106

Structural and Biochemical Rationale for Enhanced Spike Protein Fitness in Delta and Kappa SARS-CoV-2 Variants

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  • Site-wide: 57,449
  • In biochemistry: 1,488
• Year to date:
  • Site-wide: 38,379
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  • Site-wide: 85,841

Genomic selection to optimize doubled haploid-based hybrid breeding in maize

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  • Site-wide: 58,110
  • In genetics: 2,508
• Year to date:
  • Site-wide: 39,415
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  • Site-wide: 28,508

A Genome-wide CRISPR Screen Identifies WDFY3 as a Novel Regulator of Macrophage Efferocytosis

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  • Site-wide: 61,609
  • In cell biology: 4,489
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  • Site-wide: 2,504
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  • Site-wide: 3,562

Analysis of Rod/Cone Gap Junctions from the Reconstruction of Mouse Photoreceptor Terminals

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  • Site-wide: 64,999
  • In neuroscience: 10,553
• Year to date:
  • Site-wide: 24,837
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  • Site-wide: 20,462

A non-canonical EZH2 function sensitizes solid tumors to genotoxic stress

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  • Site-wide: 79,450
  • In cancer biology: 2,325
• Year to date:
  • Site-wide: 52,701
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  • Site-wide: 84,571

Abundant non-A residues in the poly(A) tail orchestrate the mouse oocyte-to-embryo transition

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  • Site-wide: 83,264
  • In developmental biology: 2,231
• Year to date:
  • Site-wide: 34,584
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  • Site-wide: 56,791

Bimodal Endocytic Probe for Three-Dimensional Correlative Light and Electron Microscopy

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  • Site-wide: 83,700
  • In cell biology: 3,774
• Year to date:
  • Site-wide: 56,777
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  • Site-wide: 56,226

Neutralization of European, South African, and United States SARS-CoV-2 mutants by a human antibody and antibody domains

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  • Site-wide: 88,862
  • In immunology: 2,751
• Year to date:
  • Site-wide: 84,040
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  • Site-wide: 56,320

Structural Analysis of Receptor Binding Domain Mutations in SARS-CoV-2 Variants of Concern that Modulate ACE2 and Antibody Binding

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  • Site-wide: 94,699
  • In biochemistry: 2,720
• Year to date:
  • Site-wide: 56,676
• Since beginning of last month:
  • Site-wide: 40,112

Whole exome sequencing identifies genes associated with non-obstructive azoospermia

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  • Site-wide: 95,474
  • In genetic and genomic medicine: 518
• Year to date:
  • Site-wide: 88,831
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  • Site-wide: 74,798

A phenotypic screen using splitCas9 identifies essential genes required for actin regulation during host cell egress and invasion by Toxoplasma gondii

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  • Site-wide: 95,730
  • In microbiology: 6,916
• Year to date:
  • Site-wide: 24,275
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  • Site-wide: 52,536

A Preliminary Retrospective and Prospective Cohort Study on a Traditional Chinese Long-term Extreme Fasting

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  • Site-wide: 98,880
  • In nutrition: 92
• Year to date:
  • Site-wide: 86,731
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  • Site-wide: 60,763

Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization

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  • Site-wide: 100,621
  • In developmental biology: 2,555
• Year to date:
  • Site-wide: 165,428
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  • Site-wide: 158,322

The 55K SNP-Based Exploration of QTL for Spikelet Number Per Spike in a Tetraploid Wheat (Triticum turgidum L.) Population: Chinese Landrace Ailanmai X Wild Emmer

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  • Site-wide: 102,369
  • In genetics: 4,142
• Year to date:
  • Site-wide: 67,640
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  • Site-wide: 116,757

Prediction of 7-year's Conversion from Subjective Cognitive Decline to Mild Cognitive Impairment

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  • Site-wide: 105,890
  • In geriatric medicine: 79
• Year to date:
  • Site-wide: 123,327
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  • Site-wide: 142,142

The Long Noncoding RNA FEDORA is a Cell-Type- and Sex-Specific Regulator of Depression

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  • Site-wide: 121,028
  • In neuroscience: 21,072
• Year to date:
  • Site-wide: 20,370
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  • Site-wide: 18,915

Conservation and divergence of poly(A) tail regulation during the mammalian oocyte-to-embryo transition

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  • Site-wide: 126,151
  • In developmental biology: 3,367
• Year to date:
  • Site-wide: 58,370
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  • Site-wide: 55,706

Association between temperature and back pain among lumbar disc herniation patients

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  • Site-wide: 129,788
  • In epidemiology: 5,367
• Year to date:
  • Site-wide: 103,874
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  • Site-wide: 83,113

The Actin Bundling Protein Fascin Promotes Lung Cancer Growth and Metastasis by Enhancing Glycolysis and PFKFB3 Expression

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  • Site-wide: 131,170
  • In cancer biology: 3,838
• Year to date:
  • Site-wide: 79,329
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  • Site-wide: 143,271

A Novel Gene ZNF862 Causes Hereditary Gingival Fibromatosis

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  • Site-wide: 137,148
  • In genetic and genomic medicine: 852
• Year to date:
  • Site-wide: 65,116
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  • Site-wide: 54,602

First genotype-phenotype study in TBX4 syndrome: gain-of-function mutations causative for lung disease

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  • Site-wide: 140,916
  • In respiratory medicine: None
• Year to date:
  • Site-wide: 8,818
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  • Site-wide: 26,132

In vivo Characterization of MRI-based T1w/T2w Ratios and Covariance Network in Temporal Lobe Epilepsy

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  • Site-wide: 141,958
  • In radiology and imaging: 321
• Year to date:
  • Site-wide: 84,960
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  • Site-wide: 62,734

Targeting Thymidine Phosphorylase with Tipiracil Hydrochloride is a Safe and Effective Antithrombotic Therapy

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  • Site-wide: 146,040
  • In cell biology: 6,563
• Year to date:
  • Site-wide: 127,333
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  • Site-wide: 108,218

Essential role of CFAP53 in sperm flagellum biogenesis

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  • Site-wide: 151,387
  • In developmental biology: 3,922
• Year to date:
  • Site-wide: 146,815
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  • Site-wide: 115,044

Cadherin-6 mediates thrombosis in vivo

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  • Site-wide: 152,045
  • In pathology: 860
• Year to date:
  • Site-wide: 133,179
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  • Site-wide: 140,222

Decoding the IGF1 Signaling Gene Regulatory Network Behind Alveologenesis from A Mouse Model of Bronchopulmonary Dysplasia

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  • Site-wide: 155,740
  • In developmental biology: 4,226
• Year to date:
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  • Site-wide: 25,903

Soluble immune checkpoints are dysregulated in COVID-19 and heavy alcohol users with HIV infection

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  • Site-wide: 163,351
  • In infectious diseases: 6,802
• Year to date:
  • Site-wide: 22,161
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  • Site-wide: 94,564

Altered effective connectivity from the posterior insula to the amygdala mediates the relationship between psychopathic traits and concern with the Harm foundation

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  • Site-wide: 169,701
  • In neuroscience: 24,264
• Year to date:
  • Site-wide: 138,337
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  • Site-wide: 110,519

PD-L1-expressing astrocytes act as a gate-keeper for neuroinflammation in the central nervous system of mice with traumatic brain injury

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  • Site-wide: 170,628
  • In neuroscience: 25,556
• Year to date:
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  • Site-wide: 37,850

First Glimpse of Gut Microbiota of Quarantine Insects in China

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  • Site-wide: 172,722
  • In microbiology: 12,769
• Year to date:
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  • Site-wide: 143,355