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Author: Douglas F. Easton

Rankings

  • All-time downloads: 36,773 (rank: 7,321 (tie) )
  • Categories:
    • bioinformatics: 377 (rank: 40,962 (tie) )
    • epidemiology: 1,712 (rank: 10,329 (tie) )
    • genetic and genomic medicine: 4,604 (rank: 1,148 )
    • genetics: 17,209 (rank: 1,007 )
    • genomics: 7,686 (rank: 3,722 (tie) )
    • molecular biology: 1,007 (rank: 9,504 (tie) )
    • sexual and reproductive health: 2,505 (rank: 158 (tie) )

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Preprints

A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries

genetics more details view paper
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Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

genomics more details view paper
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    • Site-wide: 2,799
    • In genomics: 227
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Improving reporting standards for polygenic scores in risk prediction studies

genetic and genomic medicine more details view paper
  • Downloaded 2,962 times
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    • Site-wide: 7,220
    • In genetic and genomic medicine: 40
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Genetic insights into the biological mechanisms governing human ovarian ageing

sexual and reproductive health more details view paper
  • Downloaded 2,556 times
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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

genetics more details view paper
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    • In genetics: 549
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Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

genetics more details view paper
  • Downloaded 1,898 times
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    • Site-wide: 14,077
    • In genetics: 540
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Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers

genetics more details view paper
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    • Site-wide: 18,558
    • In genetics: 749
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    • Site-wide: 104,283
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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

genomics more details view paper
  • Downloaded 1,403 times
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    • In genomics: 1,934
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Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

genetics more details view paper
  • Downloaded 1,151 times
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    • Site-wide: 30,843
    • In genetics: 1,245
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    • Site-wide: 99,787

A genetic risk score to guide age-specific, personalized prostate cancer screening

genetics more details view paper
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    • Site-wide: 34,942
    • In genetics: 1,382
  • Year to date:
    • Site-wide: 179,458
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    • Site-wide: 89,841

Chromatin interactome mapping at 139 independent breast cancer risk signals

molecular biology more details view paper
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    • Site-wide: 36,912
    • In molecular biology: 948
  • Year to date:
    • Site-wide: 173,469
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    • Site-wide: 150,321

Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers

genetics more details view paper
  • Downloaded 1,011 times
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    • Site-wide: 37,674
    • In genetics: 1,464
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    • Site-wide: 188,109
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    • Site-wide: 149,496

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

genetics more details view paper
  • Downloaded 916 times
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    • Site-wide: 43,807
    • In genetics: 1,717
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    • Site-wide: 156,477
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Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations

genetics more details view paper
  • Downloaded 915 times
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    • Site-wide: 43,874
    • In genetics: 1,757
  • Year to date:
    • Site-wide: 74,542
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    • Site-wide: 47,584

Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six Countries

epidemiology more details view paper
  • Downloaded 864 times
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    • Site-wide: 47,900
    • In epidemiology: 2,387
  • Year to date:
    • Site-wide: 124,842
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    • Site-wide: 100,933

A Comprehensive Epithelial Tubo-Ovarian Cancer Risk Prediction Model Incorporating Genetic and Epidemiological Risk Factors

genetic and genomic medicine more details view paper
  • Downloaded 665 times
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    • Site-wide: 70,122
    • In genetic and genomic medicine: 407
  • Year to date:
    • Site-wide: 41,512
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    • Site-wide: 113,700

High-throughput allelic expression imbalance analyses identify candidate breast cancer risk genes

genetics more details view paper
  • Downloaded 646 times
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    • Site-wide: 72,884
    • In genetics: 2,783
  • Year to date:
    • Site-wide: 162,728
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    • Site-wide: 94,209

Shared heritability and functional enrichment across six solid cancers

genomics more details view paper
  • Downloaded 638 times
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    • Site-wide: 74,232
    • In genomics: 4,896
  • Year to date:
    • Site-wide: 153,602
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    • Site-wide: 44,319

Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1, updates to tumour pathology and cancer incidences.

genetic and genomic medicine more details view paper
  • Downloaded 629 times
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    • Site-wide: 75,511
    • In genetic and genomic medicine: 560
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    • Site-wide: 7,308
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    • Site-wide: 12,824

Identifying 31 novel breast cancer susceptibility loci using data from genome-wide association studies conducted in Asian and European women

epidemiology more details view paper
  • Downloaded 483 times
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    • Site-wide: 103,911
    • In epidemiology: 4,447
  • Year to date:
    • Site-wide: 164,268
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    • Site-wide: 104,246

A genetic hazard score to personalize prostate cancer screening, applied to population data

genetics more details view paper
  • Downloaded 460 times
  • Download rankings, all-time:
    • Site-wide: 109,189
    • In genetics: 4,059
  • Year to date:
    • Site-wide: 202,810
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    • Site-wide: 185,600

Is the Association Between Smoking and Depression Mediated by Inflammation? A Mendelian Randomization Study.

epidemiology more details view paper
  • Downloaded 434 times
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    • Site-wide: 115,743
    • In epidemiology: 4,866
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    • Site-wide: 42,231
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Detecting rare copy number variants (CNVs) from Illumina genotyping arrays with the CamCNV pipeline: segmentation of z-scores improves detection and reliability.

bioinformatics more details view paper
  • Downloaded 407 times
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    • Site-wide: 122,677
    • In bioinformatics: 10,054
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    • Site-wide: 120,942
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    • Site-wide: 139,202

Genetic architectures of proximal and distal colorectal cancer are partly distinct

genetic and genomic medicine more details view paper
  • Downloaded 367 times
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    • Site-wide: 134,200
    • In genetic and genomic medicine: 902
  • Year to date:
    • Site-wide: 151,661
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    • Site-wide: 141,533

Rare copy number variants (CNVs) and breast cancer risk

genetics more details view paper
  • Downloaded 299 times
  • Download rankings, all-time:
    • Site-wide: 154,475
    • In genetics: 5,734
  • Year to date:
    • Site-wide: 133,402
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    • Site-wide: 115,085

The effect of sample size on polygenic hazard models for prostate cancer

genetics more details view paper
  • Downloaded 298 times
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    • Site-wide: 154,582
    • In genetics: 5,664
  • Year to date:
    • Site-wide: 201,203
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    • Site-wide: 171,266

Exome sequencing identifies novel susceptibility genes and defines the contribution of coding variants to breast cancer risk.

genetic and genomic medicine more details view paper
  • Downloaded 138 times
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    • Site-wide: 194,376
    • In genetic and genomic medicine: 1,444
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    • Site-wide: 69,478
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Segregation analysis of 17,425 population-based breast cancer families: evidence for genetic susceptibility and risk prediction

genetic and genomic medicine more details view paper
  • Downloaded 109 times
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    • Site-wide: 199,325
    • In genetic and genomic medicine: 1,489
  • Year to date:
    • Site-wide: 86,588
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