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Author: Rita E. Chen

  • Most recently observed institution: Washington University School of Medicine

Rankings

  • All-time downloads: 49,460 (rank: 2,927 )
  • Categories:
    • cell biology: 3,732 (rank: 1,167 (tie) )
    • immunology: 31,253 (rank: 278 )
    • infectious diseases: 196 (rank: 39,362 (tie) )
    • microbiology: 10,075 (rank: 1,392 )
    • synthetic biology: 4,204 (rank: 233 (tie) )

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Preprints

A potently neutralizing anti-SARS-CoV-2 antibody inhibits variants of concern by binding a highly conserved epitope

microbiology more details view paper

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Structural and functional analysis of a potent sarbecovirus neutralizing antibody

immunology more details view paper
  • Downloaded 11,800 times
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    • Site-wide: 659
    • In immunology: 19
  • Year to date:
    • Site-wide: 3,110
  • Since beginning of last month:
    • Site-wide: 4,962

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

immunology more details view paper
  • Downloaded 4,638 times
  • Download rankings, all-time:
    • Site-wide: 2,285
    • In immunology: 60
  • Year to date:
    • Site-wide: 10,492
  • Since beginning of last month:
    • Site-wide: 9,172

Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization

microbiology more details view paper
  • Downloaded 4,613 times
  • Download rankings, all-time:
    • Site-wide: 2,304
    • In microbiology: 177
  • Year to date:
    • Site-wide: 357
  • Since beginning of last month:
    • Site-wide: 1,686

Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

cell biology more details view paper
  • Downloaded 3,732 times
  • Download rankings, all-time:
    • Site-wide: 3,121
    • In cell biology: 53
  • Year to date:
    • Site-wide: 15,418
  • Since beginning of last month:
    • Site-wide: 17,926

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

immunology more details view paper
  • Downloaded 3,677 times
  • Download rankings, all-time:
    • Site-wide: 3,190
    • In immunology: 91
  • Year to date:
    • Site-wide: 6,290
  • Since beginning of last month:
    • Site-wide: 10,457

Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2.

microbiology more details view paper
  • Downloaded 3,558 times
  • Download rankings, all-time:
    • Site-wide: 3,354
    • In microbiology: 229
  • Year to date:
    • Site-wide: 9,295
  • Since beginning of last month:
    • Site-wide: 12,383

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

synthetic biology more details view paper
  • Downloaded 3,271 times
  • Download rankings, all-time:
    • Site-wide: 3,774
    • In synthetic biology: 36
  • Year to date:
    • Site-wide: 10,403
  • Since beginning of last month:
    • Site-wide: 19,252

SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function

immunology more details view paper
  • Downloaded 2,549 times
  • Download rankings, all-time:
    • Site-wide: 5,372
    • In immunology: 158
  • Year to date:
    • Site-wide: 7,434
  • Since beginning of last month:
    • Site-wide: 21,539

A single intranasal dose of chimpanzee adenovirus-vectored vaccine confers sterilizing immunity against SARS-CoV-2 infection

microbiology more details view paper
  • Downloaded 1,904 times
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    • Site-wide: 8,273
    • In microbiology: 471
  • Year to date:
    • Site-wide: 7,530
  • Since beginning of last month:
    • Site-wide: 20,540

Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail

immunology more details view paper
  • Downloaded 1,482 times
  • Download rankings, all-time:
    • Site-wide: 11,997
    • In immunology: 341
  • Year to date:
    • Site-wide: 872
  • Since beginning of last month:
    • Site-wide: 1,604

Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis

immunology more details view paper
  • Downloaded 1,405 times
  • Download rankings, all-time:
    • Site-wide: 13,018
    • In immunology: 378
  • Year to date:
    • Site-wide: 27,038
  • Since beginning of last month:
    • Site-wide: 18,656

Efficacy of a Broadly Neutralizing SARS-CoV-2 Ferritin Nanoparticle Vaccine in Nonhuman Primates

immunology more details view paper
  • Downloaded 1,176 times
  • Download rankings, all-time:
    • Site-wide: 17,026
    • In immunology: 504
  • Year to date:
    • Site-wide: 1,154
  • Since beginning of last month:
    • Site-wide: 249

A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants

immunology more details view paper
  • Downloaded 1,101 times
  • Download rankings, all-time:
    • Site-wide: 18,759
    • In immunology: 563
  • Year to date:
    • Site-wide: 1,253
  • Since beginning of last month:
    • Site-wide: 808

Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions and monocytes for optimal therapeutic protection

immunology more details view paper
  • Downloaded 1,092 times
  • Download rankings, all-time:
    • Site-wide: 18,988
    • In immunology: 572
  • Year to date:
    • Site-wide: 1,947
  • Since beginning of last month:
    • Site-wide: 7,820

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

immunology more details view paper
  • Downloaded 999 times
  • Download rankings, all-time:
    • Site-wide: 21,624
    • In immunology: 639
  • Year to date:
    • Site-wide: 2,060
  • Since beginning of last month:
    • Site-wide: 3,246

Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations

synthetic biology more details view paper
  • Downloaded 933 times
  • Download rankings, all-time:
    • Site-wide: 23,902
    • In synthetic biology: 309
  • Year to date:
    • Site-wide: 3,292
  • Since beginning of last month:
    • Site-wide: 9,537

Association between neutralizing antibodies to SARS-CoV-2 and commercial serological assays

immunology more details view paper
  • Downloaded 897 times
  • Download rankings, all-time:
    • Site-wide: 25,294
    • In immunology: 756
  • Year to date:
    • Site-wide: 13,289
  • Since beginning of last month:
    • Site-wide: 13,924

Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

immunology more details view paper
  • Downloaded 437 times
  • Download rankings, all-time:
    • Site-wide: 62,596
    • In immunology: 1,767
  • Year to date:
    • Site-wide: 4,688
  • Since beginning of last month:
    • Site-wide: 674

Assessment of serological assays for identifying high titer convalescent plasma

infectious diseases more details view paper
  • Downloaded 196 times
  • Download rankings, all-time:
    • Site-wide: 110,516
    • In infectious diseases: 4,153
  • Year to date:
    • Site-wide: 14,663
  • Since beginning of last month:
    • Site-wide: 5,931

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