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Author: Adolfo Garcia-Sastre

Rankings

  • All-time downloads: 272,708 (rank: 245 )
  • Categories:
    • biochemistry: 25,965 (rank: 35 (tie) )
    • biophysics: 482 (rank: 14,753 (tie) )
    • immunology: 1,692 (rank: 8,594 (tie) )
    • infectious diseases: 14,253 (rank: 4,941 )
    • microbiology: 49,035 (rank: 357 )
    • pharmacology and toxicology: 1,969 (rank: 653 (tie) )
    • public and global health: 809 (rank: 6,259 (tie) )
    • systems biology: 178,503 (rank: 20 (tie) )

Downloads per author, site-wide

Preprints

Recognition of HIV-1 capsid licenses innate immune response to viral infection

molecular biology more details view paper

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Type I IFN promotes pathogenic inflammatory monocyte maturation during H5N1 infection

immunology more details view paper

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Discovery of a SARS-CoV-2 Broadly-Acting Neutralizing Antibody with Activity against Omicron and Omicron + R346K Variants

microbiology more details view paper

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Nirmatrelvir, Molnupiravir, and Remdesivir maintain potent in vitro activity against the SARS-CoV-2 Omicron variant

microbiology more details view paper

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A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

systems biology more details view paper
  • Downloaded 178,503 times
  • Download rankings, all-time:
    • Site-wide: 30
    • In systems biology: 1
  • Year to date:
    • Site-wide: 1,563
  • Since beginning of last month:
    • Site-wide: 1,083

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

biochemistry more details view paper
  • Downloaded 20,073 times
  • Download rankings, all-time:
    • Site-wide: 489
    • In biochemistry: 3
  • Year to date:
    • Site-wide: 2,560
  • Since beginning of last month:
    • Site-wide: 2,349

A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals

microbiology more details view paper
  • Downloaded 16,015 times
  • Download rankings, all-time:
    • Site-wide: 628
    • In microbiology: 69
  • Year to date:
    • Site-wide: 115,731
  • Since beginning of last month:
    • Site-wide: 8,587

Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

microbiology more details view paper
  • Downloaded 6,678 times
  • Download rankings, all-time:
    • Site-wide: 1,907
    • In microbiology: 157
  • Year to date:
    • Site-wide: 1,299
  • Since beginning of last month:
    • Site-wide: 1,441

Open Science Discovery of Oral Non-Covalent SARS-CoV-2 Main Protease Inhibitor Therapeutics

biochemistry more details view paper
  • Downloaded 4,977 times
  • Download rankings, all-time:
    • Site-wide: 2,866
    • In biochemistry: 41
  • Year to date:
    • Site-wide: 1,039
  • Since beginning of last month:
    • Site-wide: 2,535

Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate

microbiology more details view paper
  • Downloaded 4,953 times
  • Download rankings, all-time:
    • Site-wide: 2,881
    • In microbiology: 218
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 21,481

Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled, Phase 1/2 Trial

infectious diseases more details view paper
  • Downloaded 4,681 times
  • Download rankings, all-time:
    • Site-wide: 3,098
    • In infectious diseases: 751
  • Year to date:
    • Site-wide: 3,081
  • Since beginning of last month:
    • Site-wide: 1,529

The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera.

infectious diseases more details view paper
  • Downloaded 3,641 times
  • Download rankings, all-time:
    • Site-wide: 4,379
    • In infectious diseases: 924
  • Year to date:
    • Site-wide: 3,610
  • Since beginning of last month:
    • Site-wide: 9,270

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

microbiology more details view paper
  • Downloaded 2,872 times
  • Download rankings, all-time:
    • Site-wide: 6,145
    • In microbiology: 389
  • Year to date:
    • Site-wide: 7,857
  • Since beginning of last month:
    • Site-wide: 13,852

The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera

infectious diseases more details view paper
  • Downloaded 2,419 times
  • Download rankings, all-time:
    • Site-wide: 7,888
    • In infectious diseases: 1,328
  • Year to date:
    • Site-wide: 6,300
  • Since beginning of last month:
    • Site-wide: 5,940

Gastrointestinal involvement attenuates COVID-19 severity and mortality

infectious diseases more details view paper
  • Downloaded 2,389 times
  • Download rankings, all-time:
    • Site-wide: 8,026
    • In infectious diseases: 1,348
  • Year to date:
    • Site-wide: 9,436
  • Since beginning of last month:
    • Site-wide: 7,959

Functional Landscape of SARS-CoV-2 Cellular Restriction

microbiology more details view paper
  • Downloaded 2,382 times
  • Download rankings, all-time:
    • Site-wide: 8,072
    • In microbiology: 482
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 13,159

Introduction of two prolines and removal of the polybasic cleavage site leads to optimal efficacy of a recombinant spike based SARS-CoV-2 vaccine in the mouse model

microbiology more details view paper
  • Downloaded 2,351 times
  • Download rankings, all-time:
    • Site-wide: 8,240
    • In microbiology: 489
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 20,020

Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

microbiology more details view paper
  • Downloaded 2,118 times
  • Download rankings, all-time:
    • Site-wide: 9,547
    • In microbiology: 558
  • Year to date:
    • Site-wide: 30,426
  • Since beginning of last month:
    • Site-wide: 28,160

A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine

microbiology more details view paper
  • Downloaded 2,031 times
  • Download rankings, all-time:
    • Site-wide: 10,184
    • In microbiology: 598
  • Year to date:
    • Site-wide: 130,252
  • Since beginning of last month:
    • Site-wide: 30,193

Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

pharmacology and toxicology more details view paper
  • Downloaded 1,969 times
  • Download rankings, all-time:
    • Site-wide: 10,674
    • In pharmacology and toxicology: 62
  • Year to date:
    • Site-wide: 17,910
  • Since beginning of last month:
    • Site-wide: 12,502

The virucidal effects of 405 nm visible light on SARS-CoV-2 and influenza A virus

microbiology more details view paper
  • Downloaded 1,761 times
  • Download rankings, all-time:
    • Site-wide: 12,592
    • In microbiology: 731
  • Year to date:
    • Site-wide: 12,571
  • Since beginning of last month:
    • Site-wide: 8,545

SARS-CoV-2 infection, disease and transmission in domestic cats

microbiology more details view paper
  • Downloaded 1,733 times
  • Download rankings, all-time:
    • Site-wide: 12,916
    • In microbiology: 744
  • Year to date:
    • Site-wide: 87,948
  • Since beginning of last month:
    • Site-wide: 107,758

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.

microbiology more details view paper
  • Downloaded 1,406 times
  • Download rankings, all-time:
    • Site-wide: 17,788
    • In microbiology: 1,029
  • Year to date:
    • Site-wide: 20,845
  • Since beginning of last month:
    • Site-wide: 22,981

Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer

microbiology more details view paper
  • Downloaded 1,320 times
  • Download rankings, all-time:
    • Site-wide: 19,547
    • In microbiology: 1,130
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 5,060

Longitudinal Metabolomics of Human Plasma Reveals Robust Prognostic Markers of COVID-19 Disease Severity

infectious diseases more details view paper
  • Downloaded 1,123 times
  • Download rankings, all-time:
    • Site-wide: 24,974
    • In infectious diseases: 2,426
  • Year to date:
    • Site-wide: 12,113
  • Since beginning of last month:
    • Site-wide: 31,411

Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant

microbiology more details view paper
  • Downloaded 1,113 times
  • Download rankings, all-time:
    • Site-wide: 25,317
    • In microbiology: 1,472
  • Year to date:
    • Site-wide: 4,534
  • Since beginning of last month:
    • Site-wide: 2,951

SARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage

microbiology more details view paper
  • Downloaded 1,057 times
  • Download rankings, all-time:
    • Site-wide: 27,411
    • In microbiology: 1,590
  • Year to date:
    • Site-wide: 92,635
  • Since beginning of last month:
    • Site-wide: 3,661

Hepatitis C Virus Drugs Simeprevir and Grazoprevir Synergize with Remdesivir to Suppress SARS-CoV-2 Replication in Cell Culture

biochemistry more details view paper
  • Downloaded 915 times
  • Download rankings, all-time:
    • Site-wide: 33,884
    • In biochemistry: 814
  • Year to date:
    • Site-wide: 24,636
  • Since beginning of last month:
    • Site-wide: 115,459

The regulatory factor ELF1 triggers a critical wave of transcription in the antiviral response to type I interferon

immunology more details view paper
  • Downloaded 889 times
  • Download rankings, all-time:
    • Site-wide: 35,324
    • In immunology: 1,172
  • Year to date:
    • Site-wide: 44,397
  • Since beginning of last month:
    • Site-wide: 82,958

Scalable, effective, and rapid decontamination of SARS-CoV-2 contaminated N95 respirators using germicidal ultra-violet C (UVC) irradiation device

public and global health more details view paper
  • Downloaded 809 times
  • Download rankings, all-time:
    • Site-wide: 40,472
    • In public and global health: 733
  • Year to date:
    • Site-wide: 39,162
  • Since beginning of last month:
    • Site-wide: 26,427

A Newcastle disease virus-vector expressing a prefusion-stabilized spike protein of SARS-CoV-2 induces protective immune responses against prototype virus and variants of concern in mice and hamsters

immunology more details view paper
  • Downloaded 803 times
  • Download rankings, all-time:
    • Site-wide: 40,929
    • In immunology: 1,346
  • Year to date:
    • Site-wide: 51,326
  • Since beginning of last month:
    • Site-wide: 30,514

Passenger mutations confound phenotypes of SARM1-deficient mice

microbiology more details view paper
  • Downloaded 680 times
  • Download rankings, all-time:
    • Site-wide: 51,758
    • In microbiology: 3,132
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 135,842

Experimental re-infected cats do not transmit SARS-CoV-2

microbiology more details view paper
  • Downloaded 565 times
  • Download rankings, all-time:
    • Site-wide: 65,699
    • In microbiology: 4,133
  • Year to date:
    • Site-wide: 111,777
  • Since beginning of last month:
    • Site-wide: 79,634

Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expression

biophysics more details view paper
  • Downloaded 482 times
  • Download rankings, all-time:
    • Site-wide: 79,163
    • In biophysics: 2,852
  • Year to date:
    • Site-wide: 54,469
  • Since beginning of last month:
    • Site-wide: 163,387

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