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Author: Wei Zheng

Rankings

  • All-time downloads: 51,768 (rank: 4,614 )
  • Categories:
    • bioengineering: 425 (rank: 12,625 (tie) )
    • bioinformatics: 1,866 (rank: 10,097 (tie) )
    • biophysics: 137 (rank: 26,297 (tie) )
    • cancer biology: 252 (rank: 38,559 (tie) )
    • cell biology: 3,169 (rank: 2,283 )
    • developmental biology: 1,917 (rank: 2,370 (tie) )
    • epidemiology: 4,081 (rank: 4,397 )
    • gastroenterology: 50 (rank: 2,805 (tie) )
    • genetic and genomic medicine: 3,393 (rank: 1,317 )
    • genetics: 8,607 (rank: 2,377 )
    • genomics: 2,302 (rank: 12,723 (tie) )
    • health systems and quality improvement: 645 (rank: 875 (tie) )
    • infectious diseases: 2,346 (rank: 20,326 (tie) )
    • microbiology: 7,078 (rank: 2,793 )
    • molecular biology: 1,842 (rank: 3,794 (tie) )
    • pharmacology and toxicology: 3,285 (rank: 365 )
    • plant biology: 2,575 (rank: 1,310 (tie) )

Downloads per author, site-wide

Preprints

CAT, AGTR2, L-SIGN and DC-SIGN are potential receptors for the entry of SARS-CoV-2 into human cells

bioinformatics more details view paper
  • Downloaded 5,217 times
  • Download rankings, all-time:
    • Site-wide: 2,995
    • In bioinformatics: 5,390
  • Year to date:
    • Site-wide: 219
  • Since beginning of last month:
    • Site-wide: 22

Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro

microbiology more details view paper
  • Downloaded 2,974 times
  • Download rankings, all-time:
    • Site-wide: 6,593
    • In microbiology: 402
  • Year to date:
    • Site-wide: 40,061
  • Since beginning of last month:
    • Site-wide: 57,861

Recurrence of SARS-CoV-2 PCR positivity in COVID-19 patients: a single center experience and potential implications

infectious diseases more details view paper
  • Downloaded 2,411 times
  • Download rankings, all-time:
    • Site-wide: 8,967
    • In infectious diseases: 1,450
  • Year to date:
    • Site-wide: 40,088
  • Since beginning of last month:
    • Site-wide: 51,261

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 2,300 times
  • Download rankings, all-time:
    • Site-wide: 9,616
    • In genetic and genomic medicine: 50
  • Year to date:
    • Site-wide: 5,887
  • Since beginning of last month:
    • Site-wide: 5,829

Identification of type 2 diabetes loci in 433,540 East Asian individuals

genetics more details view paper
  • Downloaded 2,030 times
  • Download rankings, all-time:
    • Site-wide: 11,610
    • In genetics: 433
  • Year to date:
    • Site-wide: 89,387
  • Since beginning of last month:
    • Site-wide: 85,739

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

genetics more details view paper
  • Downloaded 1,854 times
  • Download rankings, all-time:
    • Site-wide: 13,240
    • In genetics: 506
  • Year to date:
    • Site-wide: 116,966
  • Since beginning of last month:
    • Site-wide: 85,982

Carbon dots for efficient siRNA delivery and gene silencing in plants

plant biology more details view paper
  • Downloaded 1,689 times
  • Download rankings, all-time:
    • Site-wide: 15,206
    • In plant biology: 158
  • Year to date:
    • Site-wide: 64,944
  • Since beginning of last month:
    • Site-wide: 56,839

An OpenData portal to share COVID-19 drug repurposing data in real time

microbiology more details view paper
  • Downloaded 1,667 times
  • Download rankings, all-time:
    • Site-wide: 15,523
    • In microbiology: 936
  • Year to date:
    • Site-wide: 20,554
  • Since beginning of last month:
    • Site-wide: 16,967

Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro

cell biology more details view paper
  • Downloaded 1,538 times
  • Download rankings, all-time:
    • Site-wide: 17,582
    • In cell biology: 530
  • Year to date:
    • Site-wide: 34,660
  • Since beginning of last month:
    • Site-wide: 27,853

Transcriptome-wide association studies accounting for colocalization using Egger regression

epidemiology more details view paper
  • Downloaded 1,516 times
  • Download rankings, all-time:
    • Site-wide: 17,968
    • In epidemiology: 1,169
  • Year to date:
    • Site-wide: 126,268
  • Since beginning of last month:
    • Site-wide: 144,253

Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening

pharmacology and toxicology more details view paper
  • Downloaded 1,496 times
  • Download rankings, all-time:
    • Site-wide: 18,290
    • In pharmacology and toxicology: 101
  • Year to date:
    • Site-wide: 35,333
  • Since beginning of last month:
    • Site-wide: 51,198

Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

molecular biology more details view paper
  • Downloaded 1,416 times
  • Download rankings, all-time:
    • Site-wide: 19,966
    • In molecular biology: 489
  • Year to date:
    • Site-wide: 127,390
  • Since beginning of last month:
    • Site-wide: 107,377

Single-cell RNA-seq reveals distinct dynamic behavior of sex chromosomes during early human embryogenesis

developmental biology more details view paper
  • Downloaded 1,338 times
  • Download rankings, all-time:
    • Site-wide: 21,785
    • In developmental biology: 350
  • Year to date:
    • Site-wide: 53,867
  • Since beginning of last month:
    • Site-wide: 56,793

Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

pharmacology and toxicology more details view paper
  • Downloaded 1,285 times
  • Download rankings, all-time:
    • Site-wide: 23,199
    • In pharmacology and toxicology: 130
  • Year to date:
    • Site-wide: 58,816
  • Since beginning of last month:
    • Site-wide: 39,740

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 1,244 times
  • Download rankings, all-time:
    • Site-wide: 24,415
    • In genetics: 979
  • Year to date:
    • Site-wide: 90,753
  • Since beginning of last month:
    • Site-wide: 118,343

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

microbiology more details view paper
  • Downloaded 1,198 times
  • Download rankings, all-time:
    • Site-wide: 25,877
    • In microbiology: 1,448
  • Year to date:
    • Site-wide: 79,277
  • Since beginning of last month:
    • Site-wide: 53,695

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

genetics more details view paper
  • Downloaded 1,086 times
  • Download rankings, all-time:
    • Site-wide: 30,064
    • In genetics: 1,357
  • Year to date:
    • Site-wide: 33,751
  • Since beginning of last month:
    • Site-wide: 38,650

Effects of SARS-CoV-2 Mutations on Protein Structures and Intraviral Protein-Protein Interactions

microbiology more details view paper
  • Downloaded 1,029 times
  • Download rankings, all-time:
    • Site-wide: 32,547
    • In microbiology: 1,781
  • Year to date:
    • Site-wide: 129,126
  • Since beginning of last month:
    • Site-wide: 156,834

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

genetics more details view paper
  • Downloaded 801 times
  • Download rankings, all-time:
    • Site-wide: 47,186
    • In genetics: 2,071
  • Year to date:
    • Site-wide: 51,260
  • Since beginning of last month:
    • Site-wide: 15,645

Massive-scale biological activity-based modeling identifies novel antiviral leads against SARS-CoV-2

cell biology more details view paper
  • Downloaded 779 times
  • Download rankings, all-time:
    • Site-wide: 49,091
    • In cell biology: 1,941
  • Year to date:
    • Site-wide: 81,215
  • Since beginning of last month:
    • Site-wide: 88,032

Evolution of a chordate-specific mechanism for myoblast fusion

developmental biology more details view paper
  • Downloaded 771 times
  • Download rankings, all-time:
    • Site-wide: 49,825
    • In developmental biology: 1,373
  • Year to date:
    • Site-wide: 18,002
  • Since beginning of last month:
    • Site-wide: 14,798

The impact of goggle-associated harms to health and working status of nurses during management of COVID-19

health systems and quality improvement more details view paper
  • Downloaded 689 times
  • Download rankings, all-time:
    • Site-wide: 58,478
    • In health systems and quality improvement: 84
  • Year to date:
    • Site-wide: 74,430
  • Since beginning of last month:
    • Site-wide: 63,404

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 681 times
  • Download rankings, all-time:
    • Site-wide: 59,387
    • In genomics: 4,597
  • Year to date:
    • Site-wide: 24,261
  • Since beginning of last month:
    • Site-wide: 70,873

Topically delivered 22 nt siRNAs enhance RNAi silencing of endogenous genes in two species

plant biology more details view paper
  • Downloaded 661 times
  • Download rankings, all-time:
    • Site-wide: 61,872
    • In plant biology: 1,331
  • Year to date:
    • Site-wide: 101,052
  • Since beginning of last month:
    • Site-wide: 134,022

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

genetics more details view paper
  • Downloaded 613 times
  • Download rankings, all-time:
    • Site-wide: 68,281
    • In genetics: 2,611
  • Year to date:
    • Site-wide: 180,456
  • Since beginning of last month:
    • Site-wide: 170,029

Progressive and accurate assembly of multi-domain protein structures from cryo-EM density maps

bioinformatics more details view paper
  • Downloaded 605 times
  • Download rankings, all-time:
    • Site-wide: 69,476
    • In bioinformatics: 6,765
  • Year to date:
    • Site-wide: 50,109
  • Since beginning of last month:
    • Site-wide: 42,804

Shared heritability and functional enrichment across six solid cancers

genomics more details view paper
  • Downloaded 602 times
  • Download rankings, all-time:
    • Site-wide: 69,864
    • In genomics: 4,568
  • Year to date:
    • Site-wide: 163,296
  • Since beginning of last month:
    • Site-wide: 174,673

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 598 times
  • Download rankings, all-time:
    • Site-wide: 70,537
    • In genomics: 4,622
  • Year to date:
    • Site-wide: 145,015
  • Since beginning of last month:
    • Site-wide: 129,673

Evolution of myoglobin in avian lineages: positive selection for aggregation resistance in penguins and high purifying selection in galliforms

bioinformatics more details view paper
  • Downloaded 593 times
  • Download rankings, all-time:
    • Site-wide: 71,294
    • In bioinformatics: 9,325
  • Year to date:
    • Site-wide: 13,092
  • Since beginning of last month:
    • Site-wide: 5,013

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

genomics more details view paper
  • Downloaded 571 times
  • Download rankings, all-time:
    • Site-wide: 74,670
    • In genomics: 4,836
  • Year to date:
    • Site-wide: 153,671
  • Since beginning of last month:
    • Site-wide: 104,745

Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations

genetic and genomic medicine more details view paper
  • Downloaded 569 times
  • Download rankings, all-time:
    • Site-wide: 74,963
    • In genetic and genomic medicine: 377
  • Year to date:
    • Site-wide: 136,838
  • Since beginning of last month:
    • Site-wide: 103,297

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

genetics more details view paper
  • Downloaded 540 times
  • Download rankings, all-time:
    • Site-wide: 79,920
    • In genetics: 3,073
  • Year to date:
    • Site-wide: 142,270
  • Since beginning of last month:
    • Site-wide: 165,729

Evaluating causal associations between previously reported risk factors and epithelial ovarian cancer: a Mendelian randomization analysis

epidemiology more details view paper
  • Downloaded 533 times
  • Download rankings, all-time:
    • Site-wide: 81,085
    • In epidemiology: 3,438
  • Year to date:
    • Site-wide: 144,986
  • Since beginning of last month:
    • Site-wide: 140,208

Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies new candidate susceptibility genes for breast and ovarian cancer

genetics more details view paper
  • Downloaded 529 times
  • Download rankings, all-time:
    • Site-wide: 81,804
    • In genetics: 3,185
  • Year to date:
    • Site-wide: 141,150
  • Since beginning of last month:
    • Site-wide: 107,800

Development of a high-throughput homogeneous AlphaLISA drug screening assay for the detection of SARS-CoV-2 Nucleocapsid

microbiology more details view paper
  • Downloaded 510 times
  • Download rankings, all-time:
    • Site-wide: 85,548
    • In microbiology: 5,414
  • Year to date:
    • Site-wide: 106,884
  • Since beginning of last month:
    • Site-wide: 66,204

Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM

cell biology more details view paper
  • Downloaded 507 times
  • Download rankings, all-time:
    • Site-wide: 86,111
    • In cell biology: 3,583
  • Year to date:
    • Site-wide: 178,509
  • Since beginning of last month:
    • Site-wide: 157,327

Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, A Potential Oral Drug Candidate for COVID-19 Treatment

pharmacology and toxicology more details view paper
  • Downloaded 474 times
  • Download rankings, all-time:
    • Site-wide: 92,904
    • In pharmacology and toxicology: 1,091
  • Year to date:
    • Site-wide: 5,369
  • Since beginning of last month:
    • Site-wide: 12,841

Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva

molecular biology more details view paper
  • Downloaded 468 times
  • Download rankings, all-time:
    • Site-wide: 94,248
    • In molecular biology: 2,598
  • Year to date:
    • Site-wide: 151,526
  • Since beginning of last month:
    • Site-wide: 151,572

Identifying 31 novel breast cancer susceptibility loci using data from genome-wide association studies conducted in Asian and European women

epidemiology more details view paper
  • Downloaded 450 times
  • Download rankings, all-time:
    • Site-wide: 98,305
    • In epidemiology: 3,970
  • Year to date:
    • Site-wide: 168,965
  • Since beginning of last month:
    • Site-wide: 157,479

Volumetric two-photon imaging in live cells and embryos via axially gradient excitation

bioengineering more details view paper
  • Downloaded 438 times
  • Download rankings, all-time:
    • Site-wide: 101,134
    • In bioengineering: 1,832
  • Year to date:
    • Site-wide: 143,332
  • Since beginning of last month:
    • Site-wide: 162,113

Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

epidemiology more details view paper
  • Downloaded 436 times
  • Download rankings, all-time:
    • Site-wide: 101,458
    • In epidemiology: 4,121
  • Year to date:
    • Site-wide: 152,310
  • Since beginning of last month:
    • Site-wide: 136,268

A SARS-CoV-2 nucleocapsid protein TR-FRET assay amenable to high-throughput screening

pharmacology and toxicology more details view paper
  • Downloaded 433 times
  • Download rankings, all-time:
    • Site-wide: 102,278
    • In pharmacology and toxicology: 746
  • Year to date:
    • Site-wide: 51,501
  • Since beginning of last month:
    • Site-wide: 59,761

Deducing high-accuracy protein contact-maps from a triplet of coevolutionary matrices through deep residual convolutional networks

bioinformatics more details view paper
  • Downloaded 410 times
  • Download rankings, all-time:
    • Site-wide: 107,748
    • In bioinformatics: 8,591
  • Year to date:
    • Site-wide: 169,122
  • Since beginning of last month:
    • Site-wide: 182,425

Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk

epidemiology more details view paper
  • Downloaded 403 times
  • Download rankings, all-time:
    • Site-wide: 109,503
    • In epidemiology: 4,541
  • Year to date:
    • Site-wide: 62,725
  • Since beginning of last month:
    • Site-wide: 111,507

African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer

genetic and genomic medicine more details view paper
  • Downloaded 391 times
  • Download rankings, all-time:
    • Site-wide: 112,338
    • In genetic and genomic medicine: 624
  • Year to date:
    • Site-wide: 147,957
  • Since beginning of last month:
    • Site-wide: 136,498

High transgene expression is associated with systemic GFP silencing in Nicotiana benthamiana

plant biology more details view paper
  • Downloaded 390 times
  • Download rankings, all-time:
    • Site-wide: 112,570
    • In plant biology: 3,409
  • Year to date:
    • Site-wide: 43,026
  • Since beginning of last month:
    • Site-wide: 13,084

Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers

epidemiology more details view paper
  • Downloaded 381 times
  • Download rankings, all-time:
    • Site-wide: 115,010
    • In epidemiology: 4,925
  • Year to date:
    • Site-wide: 70,604
  • Since beginning of last month:
    • Site-wide: 49,389

A hybrid in silico approach reveals novel inhibitors of multiple SARS-CoV-2 variants

cell biology more details view paper
  • Downloaded 322 times
  • Download rankings, all-time:
    • Site-wide: 131,672
    • In cell biology: 5,769
  • Year to date:
    • Site-wide: 151,093
  • Since beginning of last month:
    • Site-wide: 155,028

Decoding microbiome and protein family linkage to improve protein structure prediction

bioinformatics more details view paper
  • Downloaded 306 times
  • Download rankings, all-time:
    • Site-wide: 136,213
    • In bioinformatics: 10,837
  • Year to date:
    • Site-wide: 73,593
  • Since beginning of last month:
    • Site-wide: 81,730

The association between low-density lipoprotein cholesterol predicted by HMGCR genetic variants and breast cancer risk may be mediated by body mass index

epidemiology more details view paper
  • Downloaded 288 times
  • Download rankings, all-time:
    • Site-wide: 141,799
    • In epidemiology: 5,587
  • Year to date:
    • Site-wide: 182,111
  • Since beginning of last month:
    • Site-wide: 147,715

Rare copy number variants (CNVs) and breast cancer risk

genetics more details view paper
  • Downloaded 270 times
  • Download rankings, all-time:
    • Site-wide: 146,921
    • In genetics: 5,469
  • Year to date:
    • Site-wide: 109,115
  • Since beginning of last month:
    • Site-wide: 121,922

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

cancer biology more details view paper
  • Downloaded 268 times
  • Download rankings, all-time:
    • Site-wide: 147,598
    • In cancer biology: 4,237
  • Year to date:
    • Site-wide: 158,271
  • Since beginning of last month:
    • Site-wide: 107,472

Additional SNPs improve the performance of a polygenic hazard score for prostate cancer

genetic and genomic medicine more details view paper
  • Downloaded 242 times
  • Download rankings, all-time:
    • Site-wide: 155,263
    • In genetic and genomic medicine: 953
  • Year to date:
    • Site-wide: 140,716
  • Since beginning of last month:
    • Site-wide: 123,332

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

epidemiology more details view paper
  • Downloaded 238 times
  • Download rankings, all-time:
    • Site-wide: 156,411
    • In epidemiology: 6,093
  • Year to date:
    • Site-wide: 175,893
  • Since beginning of last month:
    • Site-wide: 163,659

Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24

genetic and genomic medicine more details view paper
  • Downloaded 232 times
  • Download rankings, all-time:
    • Site-wide: 158,153
    • In genetic and genomic medicine: 959
  • Year to date:
    • Site-wide: 150,593
  • Since beginning of last month:
    • Site-wide: 125,092

Keratin5-BMP4 mechanosignaling regulates reciprocal acetylation and methylation at H3K9 to define blastema cell remodeling during zebrafish heart regeneration

cell biology more details view paper
  • Downloaded 188 times
  • Download rankings, all-time:
    • Site-wide: 169,545
    • In cell biology: 7,346
  • Year to date:
    • Site-wide: 168,633
  • Since beginning of last month:
    • Site-wide: 125,649

Protein structural features predict responsiveness to pharmacological chaperone treatment for three lysosomal storage disorders

biophysics more details view paper
  • Downloaded 152 times
  • Download rankings, all-time:
    • Site-wide: 177,611
    • In biophysics: 6,464
  • Year to date:
    • Site-wide: 135,959
  • Since beginning of last month:
    • Site-wide: 155,623

Developing and validating polygenic risk scores for colorectal cancer risk prediction in East Asians

gastroenterology more details view paper
  • Downloaded 148 times
  • Download rankings, all-time:
    • Site-wide: 178,435
    • In gastroenterology: 286
  • Year to date:
    • Site-wide: 29,156
  • Since beginning of last month:
    • Site-wide: 48,195

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