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Author: Wei Zheng

Rankings

  • All-time downloads: 37,220 (rank: 4,789 )
  • Categories:
    • bioengineering: 369 (rank: 10,556 (tie) )
    • bioinformatics: 1,380 (rank: 11,780 (tie) )
    • biophysics: 86 (rank: 22,997 (tie) )
    • cancer biology: 199 (rank: 33,529 (tie) )
    • cell biology: 2,709 (rank: 2,170 )
    • developmental biology: 1,290 (rank: 3,208 )
    • epidemiology: 3,495 (rank: 3,793 )
    • genetic and genomic medicine: 2,513 (rank: 1,347 )
    • genetics: 7,803 (rank: 2,479 )
    • genomics: 1,883 (rank: 13,336 (tie) )
    • health systems and quality improvement: 523 (rank: 808 (tie) )
    • infectious diseases: 2,160 (rank: 16,258 (tie) )
    • microbiology: 6,395 (rank: 2,480 )
    • molecular biology: 1,696 (rank: 3,365 (tie) )
    • pharmacology and toxicology: 2,479 (rank: 400 (tie) )
    • plant biology: 2,240 (rank: 1,245 (tie) )

Downloads per author, site-wide

Preprints

Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro

microbiology more details view paper
  • Downloaded 2,680 times
  • Download rankings, all-time:
    • Site-wide: 5,674
    • In microbiology: 360
  • Year to date:
    • Site-wide: 15,361
  • Since beginning of last month:
    • Site-wide: 43,623

Recurrence of SARS-CoV-2 PCR positivity in COVID-19 patients: a single center experience and potential implications

infectious diseases more details view paper
  • Downloaded 2,160 times
  • Download rankings, all-time:
    • Site-wide: 7,809
    • In infectious diseases: 1,179
  • Year to date:
    • Site-wide: 20,806
  • Since beginning of last month:
    • Site-wide: 47,360

Identification of type 2 diabetes loci in 433,540 East Asian individuals

genetics more details view paper
  • Downloaded 1,885 times
  • Download rankings, all-time:
    • Site-wide: 9,563
    • In genetics: 415
  • Year to date:
    • Site-wide: 41,738
  • Since beginning of last month:
    • Site-wide: 87,205

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

genetics more details view paper
  • Downloaded 1,736 times
  • Download rankings, all-time:
    • Site-wide: 10,781
    • In genetics: 478
  • Year to date:
    • Site-wide: 59,713
  • Since beginning of last month:
    • Site-wide: 33,938

Carbon dots for efficient siRNA delivery and gene silencing in plants

plant biology more details view paper
  • Downloaded 1,504 times
  • Download rankings, all-time:
    • Site-wide: 13,256
    • In plant biology: 146
  • Year to date:
    • Site-wide: 17,626
  • Since beginning of last month:
    • Site-wide: 88,350

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 1,440 times
  • Download rankings, all-time:
    • Site-wide: 14,198
    • In genetic and genomic medicine: 60
  • Year to date:
    • Site-wide: 6,285
  • Since beginning of last month:
    • Site-wide: 13,265

Transcriptome-wide association studies accounting for colocalization using Egger regression

epidemiology more details view paper
  • Downloaded 1,410 times
  • Download rankings, all-time:
    • Site-wide: 14,661
    • In epidemiology: 999
  • Year to date:
    • Site-wide: 119,339
  • Since beginning of last month:
    • Site-wide: 75,297

Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

molecular biology more details view paper
  • Downloaded 1,320 times
  • Download rankings, all-time:
    • Site-wide: 16,223
    • In molecular biology: 442
  • Year to date:
    • Site-wide: 60,576
  • Since beginning of last month:
    • Site-wide: None

An OpenData portal to share COVID-19 drug repurposing data in real time

microbiology more details view paper
  • Downloaded 1,316 times
  • Download rankings, all-time:
    • Site-wide: 16,308
    • In microbiology: 955
  • Year to date:
    • Site-wide: 7,240
  • Since beginning of last month:
    • Site-wide: 1,267

Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro

cell biology more details view paper
  • Downloaded 1,283 times
  • Download rankings, all-time:
    • Site-wide: 16,923
    • In cell biology: 507
  • Year to date:
    • Site-wide: 15,118
  • Since beginning of last month:
    • Site-wide: 26,049

Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening

pharmacology and toxicology more details view paper
  • Downloaded 1,198 times
  • Download rankings, all-time:
    • Site-wide: 18,711
    • In pharmacology and toxicology: 103
  • Year to date:
    • Site-wide: 11,458
  • Since beginning of last month:
    • Site-wide: 43,936

Single-cell RNA-seq reveals distinct dynamic behavior of sex chromosomes during early human embryogenesis

developmental biology more details view paper
  • Downloaded 1,093 times
  • Download rankings, all-time:
    • Site-wide: 21,420
    • In developmental biology: 365
  • Year to date:
    • Site-wide: 35,968
  • Since beginning of last month:
    • Site-wide: 65,469

Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

pharmacology and toxicology more details view paper
  • Downloaded 1,093 times
  • Download rankings, all-time:
    • Site-wide: 21,428
    • In pharmacology and toxicology: 118
  • Year to date:
    • Site-wide: 25,274
  • Since beginning of last month:
    • Site-wide: 16,515

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 1,074 times
  • Download rankings, all-time:
    • Site-wide: 22,003
    • In genetics: 1,004
  • Year to date:
    • Site-wide: 10,170
  • Since beginning of last month:
    • Site-wide: 44,082

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

microbiology more details view paper
  • Downloaded 1,028 times
  • Download rankings, all-time:
    • Site-wide: 23,424
    • In microbiology: 1,392
  • Year to date:
    • Site-wide: 16,563
  • Since beginning of last month:
    • Site-wide: 36,075

Effects of SARS-CoV-2 Mutations on Protein Structures and Intraviral Protein-Protein Interactions

microbiology more details view paper
  • Downloaded 957 times
  • Download rankings, all-time:
    • Site-wide: 26,054
    • In microbiology: 1,540
  • Year to date:
    • Site-wide: 15,627
  • Since beginning of last month:
    • Site-wide: 5,097

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

genetics more details view paper
  • Downloaded 884 times
  • Download rankings, all-time:
    • Site-wide: 29,104
    • In genetics: 1,328
  • Year to date:
    • Site-wide: 67,575
  • Since beginning of last month:
    • Site-wide: 90,221

Massive-scale biological activity-based modeling identifies novel antiviral leads against SARS-CoV-2

cell biology more details view paper
  • Downloaded 645 times
  • Download rankings, all-time:
    • Site-wide: 44,740
    • In cell biology: 1,843
  • Year to date:
    • Site-wide: 45,378
  • Since beginning of last month:
    • Site-wide: 102,140

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

genetics more details view paper
  • Downloaded 593 times
  • Download rankings, all-time:
    • Site-wide: 49,771
    • In genetics: 2,212
  • Year to date:
    • Site-wide: 29,189
  • Since beginning of last month:
    • Site-wide: 88,803

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

genetics more details view paper
  • Downloaded 574 times
  • Download rankings, all-time:
    • Site-wide: 51,855
    • In genetics: 2,298
  • Year to date:
    • Site-wide: 128,617
  • Since beginning of last month:
    • Site-wide: 72,930

Shared heritability and functional enrichment across six solid cancers

genomics more details view paper
  • Downloaded 552 times
  • Download rankings, all-time:
    • Site-wide: 54,444
    • In genomics: 4,099
  • Year to date:
    • Site-wide: 125,651
  • Since beginning of last month:
    • Site-wide: 81,777

Topically delivered 22 nt siRNAs enhance RNAi silencing of endogenous genes in two species

plant biology more details view paper
  • Downloaded 533 times
  • Download rankings, all-time:
    • Site-wide: 56,667
    • In plant biology: 1,355
  • Year to date:
    • Site-wide: 45,386
  • Since beginning of last month:
    • Site-wide: 68,330

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

genomics more details view paper
  • Downloaded 524 times
  • Download rankings, all-time:
    • Site-wide: 57,946
    • In genomics: 4,282
  • Year to date:
    • Site-wide: 145,025
  • Since beginning of last month:
    • Site-wide: None

The impact of goggle-associated harms to health and working status of nurses during management of COVID-19

health systems and quality improvement more details view paper
  • Downloaded 523 times
  • Download rankings, all-time:
    • Site-wide: 58,065
    • In health systems and quality improvement: 77
  • Year to date:
    • Site-wide: 63,297
  • Since beginning of last month:
    • Site-wide: 103,633

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 518 times
  • Download rankings, all-time:
    • Site-wide: 58,728
    • In genomics: 4,325
  • Year to date:
    • Site-wide: 141,409
  • Since beginning of last month:
    • Site-wide: None

CAT, AGTR2, L-SIGN and DC-SIGN are potential receptors for the entry of SARS-CoV-2 into human cells

bioinformatics more details view paper
  • Downloaded 509 times
  • Download rankings, all-time:
    • Site-wide: 59,814
    • In bioinformatics: 5,942
  • Year to date:
    • Site-wide: 8,317
  • Since beginning of last month:
    • Site-wide: 19,162

Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations

genetic and genomic medicine more details view paper
  • Downloaded 478 times
  • Download rankings, all-time:
    • Site-wide: 64,183
    • In genetic and genomic medicine: 258
  • Year to date:
    • Site-wide: 60,860
  • Since beginning of last month:
    • Site-wide: 46,465

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

genetics more details view paper
  • Downloaded 475 times
  • Download rankings, all-time:
    • Site-wide: 64,627
    • In genetics: 2,845
  • Year to date:
    • Site-wide: 81,312
  • Since beginning of last month:
    • Site-wide: 95,531

Evaluating causal associations between previously reported risk factors and epithelial ovarian cancer: a Mendelian randomization analysis

epidemiology more details view paper
  • Downloaded 453 times
  • Download rankings, all-time:
    • Site-wide: 68,033
    • In epidemiology: 2,964
  • Year to date:
    • Site-wide: 134,229
  • Since beginning of last month:
    • Site-wide: 61,260

Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM

cell biology more details view paper
  • Downloaded 447 times
  • Download rankings, all-time:
    • Site-wide: 68,889
    • In cell biology: 3,055
  • Year to date:
    • Site-wide: 86,659
  • Since beginning of last month:
    • Site-wide: 93,140

Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies new candidate susceptibility genes for breast and ovarian cancer

genetics more details view paper
  • Downloaded 446 times
  • Download rankings, all-time:
    • Site-wide: 69,043
    • In genetics: 3,055
  • Year to date:
    • Site-wide: 75,943
  • Since beginning of last month:
    • Site-wide: 68,491

Progressive and accurate assembly of multi-domain protein structures from cryo-EM density maps

bioinformatics more details view paper
  • Downloaded 422 times
  • Download rankings, all-time:
    • Site-wide: 73,011
    • In bioinformatics: 6,885
  • Year to date:
    • Site-wide: 58,378
  • Since beginning of last month:
    • Site-wide: 36,684

Development of a high-throughput homogeneous AlphaLISA drug screening assay for the detection of SARS-CoV-2 Nucleocapsid

microbiology more details view paper
  • Downloaded 414 times
  • Download rankings, all-time:
    • Site-wide: 74,385
    • In microbiology: 5,057
  • Year to date:
    • Site-wide: 58,985
  • Since beginning of last month:
    • Site-wide: 113,369

Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

epidemiology more details view paper
  • Downloaded 382 times
  • Download rankings, all-time:
    • Site-wide: 80,361
    • In epidemiology: 3,399
  • Year to date:
    • Site-wide: 92,221
  • Since beginning of last month:
    • Site-wide: 104,949

Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva

molecular biology more details view paper
  • Downloaded 376 times
  • Download rankings, all-time:
    • Site-wide: 81,452
    • In molecular biology: 2,374
  • Year to date:
    • Site-wide: 39,506
  • Since beginning of last month:
    • Site-wide: None

Identifying 31 novel breast cancer susceptibility loci using data from genome-wide association studies conducted in Asian and European women

epidemiology more details view paper
  • Downloaded 371 times
  • Download rankings, all-time:
    • Site-wide: 82,319
    • In epidemiology: 3,486
  • Year to date:
    • Site-wide: 94,015
  • Since beginning of last month:
    • Site-wide: 40,164

Volumetric two-photon imaging in live cells and embryos via axially gradient excitation

bioengineering more details view paper
  • Downloaded 369 times
  • Download rankings, all-time:
    • Site-wide: 82,800
    • In bioengineering: 1,556
  • Year to date:
    • Site-wide: 134,654
  • Since beginning of last month:
    • Site-wide: 84,679

Deducing high-accuracy protein contact-maps from a triplet of coevolutionary matrices through deep residual convolutional networks

bioinformatics more details view paper
  • Downloaded 344 times
  • Download rankings, all-time:
    • Site-wide: 87,850
    • In bioinformatics: 7,887
  • Year to date:
    • Site-wide: 39,520
  • Since beginning of last month:
    • Site-wide: 44,817

African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer

genetic and genomic medicine more details view paper
  • Downloaded 297 times
  • Download rankings, all-time:
    • Site-wide: 98,267
    • In genetic and genomic medicine: 457
  • Year to date:
    • Site-wide: 98,629
  • Since beginning of last month:
    • Site-wide: 104,251

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 289 times
  • Download rankings, all-time:
    • Site-wide: 100,202
    • In genomics: 6,065
  • Year to date:
    • Site-wide: 63,162
  • Since beginning of last month:
    • Site-wide: 23,775

The association between low-density lipoprotein cholesterol predicted by HMGCR genetic variants and breast cancer risk may be mediated by body mass index

epidemiology more details view paper
  • Downloaded 228 times
  • Download rankings, all-time:
    • Site-wide: 114,981
    • In epidemiology: 4,804
  • Year to date:
    • Site-wide: 135,912
  • Since beginning of last month:
    • Site-wide: None

Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers

epidemiology more details view paper
  • Downloaded 224 times
  • Download rankings, all-time:
    • Site-wide: 115,912
    • In epidemiology: 4,861
  • Year to date:
    • Site-wide: 26,211
  • Since beginning of last month:
    • Site-wide: 115,765

Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk

epidemiology more details view paper
  • Downloaded 222 times
  • Download rankings, all-time:
    • Site-wide: 116,587
    • In epidemiology: 4,880
  • Year to date:
    • Site-wide: 51,717
  • Since beginning of last month:
    • Site-wide: 116,202

A hybrid in silico approach reveals novel inhibitors of multiple SARS-CoV-2 variants

cell biology more details view paper
  • Downloaded 211 times
  • Download rankings, all-time:
    • Site-wide: 119,171
    • In cell biology: 5,481
  • Year to date:
    • Site-wide: 28,288
  • Since beginning of last month:
    • Site-wide: 24,968

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

epidemiology more details view paper
  • Downloaded 205 times
  • Download rankings, all-time:
    • Site-wide: 120,622
    • In epidemiology: 5,053
  • Year to date:
    • Site-wide: 146,704
  • Since beginning of last month:
    • Site-wide: None

High transgene expression is associated with systemic GFP silencing in Nicotiana benthamiana

plant biology more details view paper
  • Downloaded 203 times
  • Download rankings, all-time:
    • Site-wide: 121,136
    • In plant biology: 3,359
  • Year to date:
    • Site-wide: 29,598
  • Since beginning of last month:
    • Site-wide: 15,743

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

cancer biology more details view paper
  • Downloaded 199 times
  • Download rankings, all-time:
    • Site-wide: 122,263
    • In cancer biology: 3,700
  • Year to date:
    • Site-wide: 98,504
  • Since beginning of last month:
    • Site-wide: None

Evolution of a chordate-specific mechanism for myoblast fusion

developmental biology more details view paper
  • Downloaded 197 times
  • Download rankings, all-time:
    • Site-wide: 122,638
    • In developmental biology: 3,281
  • Year to date:
    • Site-wide: 30,714
  • Since beginning of last month:
    • Site-wide: 8,159

A SARS-CoV-2 nucleocapsid protein TR-FRET assay amenable to high-throughput screening

pharmacology and toxicology more details view paper
  • Downloaded 188 times
  • Download rankings, all-time:
    • Site-wide: 124,752
    • In pharmacology and toxicology: 984
  • Year to date:
    • Site-wide: 32,547
  • Since beginning of last month:
    • Site-wide: 55,087

Additional SNPs improve the performance of a polygenic hazard score for prostate cancer

genetic and genomic medicine more details view paper
  • Downloaded 153 times
  • Download rankings, all-time:
    • Site-wide: 133,038
    • In genetic and genomic medicine: 722
  • Year to date:
    • Site-wide: 104,702
  • Since beginning of last month:
    • Site-wide: 48,996

Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24

genetic and genomic medicine more details view paper
  • Downloaded 145 times
  • Download rankings, all-time:
    • Site-wide: 134,818
    • In genetic and genomic medicine: 733
  • Year to date:
    • Site-wide: 43,884
  • Since beginning of last month:
    • Site-wide: None

Rare copy number variants (CNVs) and breast cancer risk

genetics more details view paper
  • Downloaded 136 times
  • Download rankings, all-time:
    • Site-wide: 136,724
    • In genetics: 5,519
  • Year to date:
    • Site-wide: 47,038
  • Since beginning of last month:
    • Site-wide: 18,513

Keratin5-BMP4 mechanosignaling regulates reciprocal acetylation and methylation at H3K9 to define blastema cell remodeling during zebrafish heart regeneration

cell biology more details view paper
  • Downloaded 123 times
  • Download rankings, all-time:
    • Site-wide: 139,489
    • In cell biology: 6,341
  • Year to date:
    • Site-wide: 113,391
  • Since beginning of last month:
    • Site-wide: 109,481

Decoding microbiome and protein family linkage to improve protein structure prediction

bioinformatics more details view paper
  • Downloaded 105 times
  • Download rankings, all-time:
    • Site-wide: 142,883
    • In bioinformatics: 11,046
  • Year to date:
    • Site-wide: 60,148
  • Since beginning of last month:
    • Site-wide: 53,020

Protein structural features predict responsiveness to pharmacological chaperone treatment for three lysosomal storage disorders

biophysics more details view paper
  • Downloaded 86 times
  • Download rankings, all-time:
    • Site-wide: 146,056
    • In biophysics: 5,596
  • Year to date:
    • Site-wide: 72,042
  • Since beginning of last month:
    • Site-wide: 25,020

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