Author: Dennis R. Burton

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Preprints

Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion

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  • Site-wide: 1,306
  • In immunology: 29
• Year to date:
  • Site-wide: 25,739
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  • Site-wide: 27,390

Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model

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  • Site-wide: 1,592
  • In immunology: 39
• Year to date:
  • Site-wide: 8,354
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  • Site-wide: 6,170

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

• Downloaded 4,709 times
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  • Site-wide: 2,171
  • In genomics: 231
• Year to date:
  • Site-wide: 26,062
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  • Site-wide: 27,461

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

• Downloaded 2,268 times
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  • Site-wide: 6,222
  • In immunology: 185
• Year to date:
  • Site-wide: 18,424
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  • Site-wide: 17,873

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

• Downloaded 2,189 times
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  • Site-wide: 6,530
  • In immunology: 191
• Year to date:
  • Site-wide: 3,093
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  • Site-wide: 3,195

Structural basis of a public antibody response to SARS-CoV-2

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  • Site-wide: 7,803
  • In microbiology: 435
• Year to date:
  • Site-wide: 17,226
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  • Site-wide: 19,947

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

• Downloaded 1,417 times
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  • Site-wide: 12,464
  • In immunology: 351
• Year to date:
  • Site-wide: 3,063
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  • Site-wide: 5,267

Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

• Downloaded 1,217 times
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  • Site-wide: 15,725
  • In immunology: 451
• Year to date:
  • Site-wide: 105,691
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  • Site-wide: 105,739

Oral drug repositioning candidates and synergistic remdesivir combinations for the prophylaxis and treatment of COVID-19

• Downloaded 1,212 times
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  • Site-wide: 15,819
  • In microbiology: 905
• Year to date:
  • Site-wide: 13,398
• Since beginning of last month:
  • Site-wide: 10,847

Massively scalable genetic analysis of antibody repertoires

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  • Site-wide: 17,146
  • In bioinformatics: 2,068
• Year to date:
  • Site-wide: 40,444
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  • Site-wide: 29,608

Reprogramming the antigen specificity of B cells using genome-editing technologies

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  • Site-wide: 24,063
  • In immunology: 703
• Year to date:
  • Site-wide: 43,211
• Since beginning of last month:
  • Site-wide: 40,125

AI-guided discovery of the invariant host response to viral pandemics

• Downloaded 792 times
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  • Site-wide: 29,211
  • In bioinformatics: 3,348
• Year to date:
  • Site-wide: 13,832
• Since beginning of last month:
  • Site-wide: 18,408

A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes

• Downloaded 755 times
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  • Site-wide: 31,224
  • In immunology: 898
• Year to date:
  • Site-wide: 1,627
• Since beginning of last month:
  • Site-wide: 471

Haplotype-phased synthetic long reads from short-read sequencing

• Downloaded 724 times
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  • Site-wide: 33,138
  • In genomics: 2,922
• Year to date:
  • Site-wide: 110,375
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  • Site-wide: 110,180

HIV-1 vaccine design through minimizing envelope metastability

• Downloaded 666 times
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  • Site-wide: 37,051
  • In microbiology: 2,214
• Year to date:
  • Site-wide: 110,133
• Since beginning of last month:
  • Site-wide: 113,074

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

• Downloaded 662 times
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  • Site-wide: 37,327
  • In microbiology: 2,230
• Year to date:
  • Site-wide: 1,979
• Since beginning of last month:
  • Site-wide: 1,591

Mapping polyclonal antibody responses in non-human primates vaccinated with HIV Env trimer subunit vaccines

• Downloaded 592 times
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  • Site-wide: 43,084
  • In immunology: 1,208
• Year to date:
  • Site-wide: 48,126
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  • Site-wide: 29,155

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

• Downloaded 574 times
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  • Site-wide: 44,731
  • In immunology: 1,256
• Year to date:
  • Site-wide: 99,059
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  • Site-wide: 101,790

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

• Downloaded 563 times
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  • Site-wide: 45,791
  • In immunology: 1,273
• Year to date:
  • Site-wide: 69,323
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  • Site-wide: 84,881

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

• Downloaded 530 times
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  • Site-wide: 49,213
  • In immunology: 1,382
• Year to date:
  • Site-wide: 121,490
• Since beginning of last month:
  • Site-wide: 105,989

Vaccine Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cells

• Downloaded 506 times
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  • Site-wide: 52,097
  • In immunology: 1,465
• Year to date:
  • Site-wide: 77,662
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  • Site-wide: 80,091

Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing

• Downloaded 455 times
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  • Site-wide: 58,609
  • In immunology: 1,629
• Year to date:
  • Site-wide: 107,775
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  • Site-wide: 81,480

Site-specific steric control of SARS-CoV-2 spike glycosylation

• Downloaded 408 times
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  • Site-wide: 65,462
  • In biochemistry: 1,784
• Year to date:
  • Site-wide: 3,892
• Since beginning of last month:
  • Site-wide: 1,114

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

• Downloaded 351 times
• Download rankings, all-time:
  • Site-wide: 75,085
  • In immunology: 2,099
• Year to date:
  • Site-wide: 4,856
• Since beginning of last month:
  • Site-wide: 11,046

Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened

• Downloaded 329 times
• Download rankings, all-time:
  • Site-wide: 79,304
  • In immunology: 2,203
• Year to date:
  • Site-wide: 116,640
• Since beginning of last month:
  • Site-wide: 132,867

HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite

• Downloaded 298 times
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  • Site-wide: 85,634
  • In immunology: 2,389
• Year to date:
  • Site-wide: 121,895
• Since beginning of last month:
  • Site-wide: 133,211

Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

• Downloaded 292 times
• Download rankings, all-time:
  • Site-wide: 86,747
  • In immunology: 2,430
• Year to date:
  • Site-wide: 6,380
• Since beginning of last month:
  • Site-wide: 7,066