Author: Dennis R. Burton

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Preprints

Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion

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  • Site-wide: 33,190

Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model

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  • Site-wide: 2,021
  • In immunology: 69
• Year to date:
  • Site-wide: 15,351
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  • Site-wide: 51,098

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

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  • Site-wide: 2,754
  • In genomics: 258
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  • Site-wide: 131,989

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

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  • Site-wide: 6,464
  • In immunology: 234
• Year to date:
  • Site-wide: 5,624
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  • Site-wide: 97,895

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

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  • Site-wide: 7,005
  • In immunology: 246
• Year to date:
  • Site-wide: 21,838
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  • Site-wide: 39,885

Structural basis of a public antibody response to SARS-CoV-2

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  • Site-wide: 8,730
  • In microbiology: 519
• Year to date:
  • Site-wide: 23,424
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  • Site-wide: 65,051

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

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  • Site-wide: 11,107
  • In immunology: 383
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A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes

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  • Site-wide: 11,409
  • In immunology: 398
• Year to date:
  • Site-wide: 2,226
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  • Site-wide: 6,603

Oral drug repositioning candidates and synergistic remdesivir combinations for the prophylaxis and treatment of COVID-19

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  • Site-wide: 15,916
  • In microbiology: 924
• Year to date:
  • Site-wide: 20,108
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  • Site-wide: 79,938

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

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  • Site-wide: 18,060
  • In microbiology: 1,046
• Year to date:
  • Site-wide: 3,444
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Massively scalable genetic analysis of antibody repertoires

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  • Site-wide: 18,667
  • In bioinformatics: 2,110
• Year to date:
  • Site-wide: 45,895
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  • Site-wide: 74,610

Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

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  • Site-wide: 20,114
  • In immunology: 703
• Year to date:
  • Site-wide: 147,723
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  • Site-wide: 159,538

AI-guided discovery of the invariant host response to viral pandemics

• Downloaded 1,221 times
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  • Site-wide: 21,130
  • In bioinformatics: 2,391
• Year to date:
  • Site-wide: 12,199
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  • Site-wide: 19,758

Reprogramming the antigen specificity of B cells using genome-editing technologies

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  • Site-wide: 27,075
  • In immunology: 917
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  • Site-wide: 62,814
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  • Site-wide: 74,601

HIV-1 vaccine design through minimizing envelope metastability

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  • Site-wide: 28,246
  • In microbiology: 1,646
• Year to date:
  • Site-wide: 26,574
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  • Site-wide: 152,414

Site-specific steric control of SARS-CoV-2 spike glycosylation

• Downloaded 994 times
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  • Site-wide: 28,779
  • In biochemistry: 669
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  • Site-wide: 5,434
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  • Site-wide: 14,402

Haplotype-phased synthetic long reads from short-read sequencing

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  • Site-wide: 42,546
  • In genomics: 3,374
• Year to date:
  • Site-wide: 153,371
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  • Site-wide: 142,302

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

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  • Site-wide: 45,212
  • In immunology: 1,434
• Year to date:
  • Site-wide: 8,872
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  • Site-wide: 7,396

Mapping polyclonal antibody responses in non-human primates vaccinated with HIV Env trimer subunit vaccines

• Downloaded 667 times
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  • Site-wide: 51,026
  • In immunology: 1,596
• Year to date:
  • Site-wide: 93,267
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  • Site-wide: 119,637

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

• Downloaded 642 times
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  • Site-wide: 53,745
  • In immunology: 1,669
• Year to date:
  • Site-wide: 123,871
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  • Site-wide: 138,275

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

• Downloaded 615 times
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  • Site-wide: 56,861
  • In immunology: 1,752
• Year to date:
  • Site-wide: 125,824
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  • Site-wide: 146,764

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

• Downloaded 558 times
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  • Site-wide: 64,158
  • In immunology: 1,973
• Year to date:
  • Site-wide: 160,248
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  • Site-wide: 151,641

Vaccine Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cells

• Downloaded 546 times
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  • Site-wide: 65,987
  • In immunology: 2,013
• Year to date:
  • Site-wide: 141,352
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  • Site-wide: 150,872

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

• Downloaded 512 times
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  • Site-wide: 71,093
  • In immunology: 2,173
• Year to date:
  • Site-wide: 15,327
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  • Site-wide: 37,245

Targeted isolation of panels of diverse human broadly neutralizing antibodies against SARS-like viruses

• Downloaded 504 times
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  • Site-wide: 72,507
  • In immunology: 2,212
• Year to date:
  • Site-wide: 15,742
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  • Site-wide: 12,990

Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing

• Downloaded 483 times
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  • Site-wide: 76,046
  • In immunology: 2,306
• Year to date:
  • Site-wide: 157,593
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  • Site-wide: 151,231

Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

• Downloaded 477 times
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  • Site-wide: 77,200
  • In immunology: 2,337
• Year to date:
  • Site-wide: 17,165
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  • Site-wide: 60,427

Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened

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  • Site-wide: 101,915
  • In immunology: 3,052
• Year to date:
  • Site-wide: 158,239
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  • Site-wide: 150,895

HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite

• Downloaded 331 times
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  • Site-wide: 108,546
  • In immunology: 3,264
• Year to date:
  • Site-wide: 157,595
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  • Site-wide: 155,281