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Author: Xu Zhang

Rankings

  • All-time downloads: 90,017 (rank: 2,398 )
  • Categories:
    • biochemistry: 870 (rank: 9,072 (tie) )
    • bioengineering: 531 (rank: 10,556 (tie) )
    • bioinformatics: 1,399 (rank: 13,805 (tie) )
    • cancer biology: 3,546 (rank: 1,774 )
    • cell biology: 5,139 (rank: 1,141 )
    • developmental biology: 3,516 (rank: 954 )
    • epidemiology: 536 (rank: 21,205 (tie) )
    • evolutionary biology: 1,358 (rank: 6,116 (tie) )
    • genomics: 2,669 (rank: 10,835 (tie) )
    • immunology: 485 (rank: 27,273 (tie) )
    • infectious diseases: 761 (rank: 37,930 (tie) )
    • intensive care and critical care medicine: 473 (rank: 2,530 (tie) )
    • microbiology: 48,961 (rank: 364 )
    • molecular biology: 1,345 (rank: 5,616 (tie) )
    • neuroscience: 9,268 (rank: 2,077 (tie) )
    • pathology: 226 (rank: 7,657 (tie) )
    • public and global health: 2,426 (rank: 2,413 (tie) )
    • synthetic biology: 587 (rank: 4,454 (tie) )
    • systems biology: 1,416 (rank: 3,875 (tie) )

Downloads per author, site-wide

Preprints

Genomic analyses provide new insights into the evolutionary history and reproduction of the Paleogene relictual Kingdonia (Circaeasteraceae, Ranunculales)

genomics more details view paper

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Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins

microbiology more details view paper
  • Downloaded 17,741 times
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    • Site-wide: 616
    • In microbiology: 65
  • Year to date:
    • Site-wide: 5,571
  • Since beginning of last month:
    • Site-wide: 6,180

The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I

microbiology more details view paper
  • Downloaded 16,850 times
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    • Site-wide: 656
    • In microbiology: 68
  • Year to date:
    • Site-wide: 6,686
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    • Site-wide: 10,113

Glycopeptide antibiotic teicoplanin inhibits cell entry of SARS-CoV-2 by suppressing the proteolytic activity of cathepsin L

microbiology more details view paper
  • Downloaded 8,214 times
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    • Site-wide: 1,634
    • In microbiology: 146
  • Year to date:
    • Site-wide: 18,811
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    • Site-wide: 20,896

Variability in the analysis of a single neuroimaging dataset by many teams

neuroscience more details view paper
  • Downloaded 6,987 times
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    • Site-wide: 2,017
    • In neuroscience: 85
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    • Site-wide: 46,686
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    • Site-wide: 52,453

A versatile two-step CRISPR- and RMCE-based strategy for efficient genome engineering in Drosophila

developmental biology more details view paper
  • Downloaded 2,985 times
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    • Site-wide: 6,566
    • In developmental biology: 63
  • Year to date:
    • Site-wide: 152,740
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    • Site-wide: 150,129

Quantitative analysis of SARS-CoV-2 RNA from wastewater solids in communities with low COVID-19 incidence and prevalence

public and global health more details view paper
  • Downloaded 2,545 times
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    • Site-wide: 8,308
    • In public and global health: 225
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    • Site-wide: 20,668
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    • Site-wide: 42,955

SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation

microbiology more details view paper
  • Downloaded 2,068 times
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    • Site-wide: 11,298
    • In microbiology: 981
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    • Site-wide: 618
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A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

cell biology more details view paper
  • Downloaded 2,052 times
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    • Site-wide: 11,444
    • In cell biology: 605
  • Year to date:
    • Site-wide: 1,353
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    • Site-wide: 1,702

3D observation of large-scale subcellular dynamics in vivo at the millisecond scale

cell biology more details view paper
  • Downloaded 1,555 times
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    • Site-wide: 17,314
    • In cell biology: 463
  • Year to date:
    • Site-wide: 133,280
  • Since beginning of last month:
    • Site-wide: 160,894

Single-cell RNA-seq reveals endoimmune cells in zebrafish

cell biology more details view paper
  • Downloaded 1,185 times
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    • Site-wide: 26,328
    • In cell biology: 863
  • Year to date:
    • Site-wide: 106,051
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    • Site-wide: 90,682

Imaging chromatin interactions at sub-kilobase resolution Via Tn5-FISH

cell biology more details view paper
  • Downloaded 1,114 times
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    • Site-wide: 28,938
    • In cell biology: 975
  • Year to date:
    • Site-wide: 106,948
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    • Site-wide: 164,938

A ribosome assembly stress response regulates transcription to maintain proteome homeostasis

molecular biology more details view paper
  • Downloaded 1,036 times
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    • Site-wide: 32,223
    • In molecular biology: 811
  • Year to date:
    • Site-wide: 113,342
  • Since beginning of last month:
    • Site-wide: 116,400

RapidAIM: A culture- and metaproteomics-based Rapid Assay of Individual Microbiome responses to drugs

microbiology more details view paper
  • Downloaded 1,020 times
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    • Site-wide: 33,028
    • In microbiology: 1,797
  • Year to date:
    • Site-wide: 156,501
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    • Site-wide: 130,249

Control of mammalian brain aging by the unfolded protein response (UPR)

neuroscience more details view paper
  • Downloaded 991 times
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    • Site-wide: 34,455
    • In neuroscience: 4,404
  • Year to date:
    • Site-wide: 52,651
  • Since beginning of last month:
    • Site-wide: 68,031

MyoD is a structure organizer of 3D genome architecture in muscle cells

genomics more details view paper
  • Downloaded 951 times
  • Download rankings, all-time:
    • Site-wide: 36,676
    • In genomics: 2,921
  • Year to date:
    • Site-wide: 55,304
  • Since beginning of last month:
    • Site-wide: 62,047

Pathogenicity, tissue tropism and potential vertical transmission of SARSr-CoV-2 in Malayan pangolins

microbiology more details view paper
  • Downloaded 895 times
  • Download rankings, all-time:
    • Site-wide: 40,062
    • In microbiology: 2,358
  • Year to date:
    • Site-wide: 76,584
  • Since beginning of last month:
    • Site-wide: 122,070

Genome wide sequencing provides evidence of adaptation to heterogeneous environments for the ancient relictual Circaeaster agrestis (Circaeasteraceae, Ranunculales)

evolutionary biology more details view paper
  • Downloaded 883 times
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    • Site-wide: 40,859
    • In evolutionary biology: 1,880
  • Year to date:
    • Site-wide: 42,453
  • Since beginning of last month:
    • Site-wide: 47,023

DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA as Diagnostic Biomarkers for Human Cancers

cancer biology more details view paper
  • Downloaded 880 times
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    • Site-wide: 41,071
    • In cancer biology: 1,021
  • Year to date:
    • Site-wide: 160,194
  • Since beginning of last month:
    • Site-wide: 176,813

Performance of a point of care test for detecting IgM and IgG antibodies against SARS-CoV-2 and seroprevalence in blood donors and health care workers in Panama

infectious diseases more details view paper
  • Downloaded 801 times
  • Download rankings, all-time:
    • Site-wide: 47,232
    • In infectious diseases: 3,420
  • Year to date:
    • Site-wide: 68,753
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    • Site-wide: 56,071

MetaLab 2.0 enables accurate post-translational modifications profiling in metaproteomics

bioinformatics more details view paper
  • Downloaded 751 times
  • Download rankings, all-time:
    • Site-wide: 51,839
    • In bioinformatics: 5,269
  • Year to date:
    • Site-wide: 57,244
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Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity

cancer biology more details view paper
  • Downloaded 750 times
  • Download rankings, all-time:
    • Site-wide: 51,973
    • In cancer biology: 1,339
  • Year to date:
    • Site-wide: 160,094
  • Since beginning of last month:
    • Site-wide: 162,608

Real-time environmental monitoring of contaminants using living electronic sensors

synthetic biology more details view paper
  • Downloaded 732 times
  • Download rankings, all-time:
    • Site-wide: 53,735
    • In synthetic biology: 780
  • Year to date:
    • Site-wide: 22,761
  • Since beginning of last month:
    • Site-wide: 11,876

Growth phase-dependent responses of an in vitro gut microbiome to metformin

microbiology more details view paper
  • Downloaded 723 times
  • Download rankings, all-time:
    • Site-wide: 54,693
    • In microbiology: 3,278
  • Year to date:
    • Site-wide: 66,587
  • Since beginning of last month:
    • Site-wide: 68,131

Multiple expression assessments of ACE2 and TMPRSS2 SARS-CoV-2 entry molecules in the urinary tract and their associations with clinical manifestations of COVID-19

biochemistry more details view paper
  • Downloaded 712 times
  • Download rankings, all-time:
    • Site-wide: 55,865
    • In biochemistry: 1,381
  • Year to date:
    • Site-wide: 112,569
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    • Site-wide: 85,154

Non-invasive Amelioration of Essential Tremor via Phase-Locked Disruption of its Temporal Coherence

neuroscience more details view paper
  • Downloaded 681 times
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    • Site-wide: 59,452
    • In neuroscience: 8,521
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    • Site-wide: 69,274
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    • Site-wide: 121,902

5-Hydroxymethylcytosines from Circulating Cell-free DNA as Diagnostic and Prognostic Markers for Hepatocellular Carcinoma

cancer biology more details view paper
  • Downloaded 629 times
  • Download rankings, all-time:
    • Site-wide: 66,121
    • In cancer biology: 1,754
  • Year to date:
    • Site-wide: 174,869
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    • Site-wide: 162,094

A Chemoenzymatic Method for Glycoproteomic N-glycan Type Quantitation

systems biology more details view paper
  • Downloaded 624 times
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    • Site-wide: 66,767
    • In systems biology: 1,387
  • Year to date:
    • Site-wide: 93,854
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    • Site-wide: 61,489

Cholecystokinin release triggered by presynaptic NMDA receptors produces LTP and sound-sound associative memory formation

neuroscience more details view paper
  • Downloaded 609 times
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    • Site-wide: 68,932
    • In neuroscience: 9,330
  • Year to date:
    • Site-wide: 129,745
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    • Site-wide: 105,715

A general model to explain repeated turnovers of sex determination in the Salicaceae

genomics more details view paper
  • Downloaded 597 times
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    • Site-wide: 70,703
    • In genomics: 4,583
  • Year to date:
    • Site-wide: 181,424
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    • Site-wide: 168,923

Modeling SARS-CoV-2 infection in vitro with a human intestine-on-chip device

bioengineering more details view paper
  • Downloaded 566 times
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    • Site-wide: 75,625
    • In bioengineering: 1,429
  • Year to date:
    • Site-wide: 87,237
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    • Site-wide: 84,416

Metaproteomic responses of in vitro gut microbiomes to resistant starches: the role of resistant starch type and inter-individual variations

microbiology more details view paper
  • Downloaded 560 times
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    • Site-wide: 76,637
    • In microbiology: 4,607
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    • Site-wide: 140,705
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Systematic transcriptomics reveals a biphasic mode of sarcomere morphogenesis in flight muscles regulated by Spalt

developmental biology more details view paper
  • Downloaded 560 times
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    • Site-wide: 76,592
    • In developmental biology: 1,773
  • Year to date:
    • Site-wide: 129,195
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    • Site-wide: 142,869

Catching a resurgence: Increase in SARS-CoV-2 viral RNA identified in wastewater 48 hours before COVID-19 clinical tests and 96 hours before hospitalizations

epidemiology more details view paper
  • Downloaded 560 times
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    • Site-wide: 76,655
    • In epidemiology: 3,303
  • Year to date:
    • Site-wide: 115,743
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    • Site-wide: 180,660

pepFunk, a tool for peptide-centric functional analysis in metaproteomic human gut microbiome studies

bioinformatics more details view paper
  • Downloaded 551 times
  • Download rankings, all-time:
    • Site-wide: 78,139
    • In bioinformatics: 6,911
  • Year to date:
    • Site-wide: 122,691
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    • Site-wide: 126,119

Quantitative mass spectrometry to interrogate proteomic heterogeneity in metastatic lung adenocarcinoma and validate a novel somatic mutation CDK12-G879V

cancer biology more details view paper
  • Downloaded 542 times
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    • Site-wide: 79,720
    • In cancer biology: 2,144
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    • Site-wide: 148,773
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    • Site-wide: 174,222

Global proteome and phosphoproteome alterations in third generation EGFR TKI resistance reveal drug targets to circumvent resistance

cancer biology more details view paper
  • Downloaded 511 times
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    • Site-wide: 85,559
    • In cancer biology: 2,501
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    • Site-wide: 81,503
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    • Site-wide: 84,638

Different Incidence of Acute Kidney Injury In Adult Patients Receiving Different types Extracorporeal Membrane Oxygenation: A Meta-Analysis

intensive care and critical care medicine more details view paper
  • Downloaded 495 times
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    • Site-wide: 88,632
    • In intensive care and critical care medicine: 216
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    • Site-wide: 116,598
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In Vitro Potent Activity of ε-poly-L-lysine against Candida albicans and the Underlying Mechanisms

microbiology more details view paper
  • Downloaded 473 times
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    • Site-wide: 93,220
    • In microbiology: 5,824
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    • Site-wide: 124,860
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De novo assembly of trachidermus fasciatus genome by nanopore sequencing

genomics more details view paper
  • Downloaded 470 times
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    • Site-wide: 93,943
    • In genomics: 5,674
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    • Site-wide: 127,868
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Deep characterization of the protein lysine acetylation in human gut microbiome and its alterations in patients with Crohn's disease

systems biology more details view paper
  • Downloaded 434 times
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    • Site-wide: 102,200
    • In systems biology: 2,076
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    • Site-wide: 167,950
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    • Site-wide: 138,319

The draft genome of the endangered, relictual plant Kingdonia uniflora (Circaeasteraceae, Ranunculales) reveals potential mechanisms and perils of evolutionary specialization

genomics more details view paper
  • Downloaded 430 times
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    • Site-wide: 103,135
    • In genomics: 5,963
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    • Site-wide: 131,458
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    • Site-wide: 101,915

Proteogenomic analysis unveils the HLA Class I presented immunopeptidome in melanoma and EGFR mutant lung adenocarcinoma

immunology more details view paper
  • Downloaded 421 times
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    • Site-wide: 105,332
    • In immunology: 3,168
  • Year to date:
    • Site-wide: 91,154
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    • Site-wide: 54,167

An in vitro model maintaining taxon-specific functional activities of the gut microbiome

microbiology more details view paper
  • Downloaded 419 times
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    • Site-wide: 105,679
    • In microbiology: 6,669
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    • Site-wide: 178,786
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    • Site-wide: 178,070

Genomic characterization of a lumpy skin disease virus isolated in southeast China

genomics more details view paper
  • Downloaded 413 times
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    • Site-wide: 107,254
    • In genomics: 6,675
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    • Site-wide: 36,474
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    • Site-wide: 47,390

Studying the dynamics of the gut microbiota using metabolically stable isotopic labeling and metaproteomics.

microbiology more details view paper
  • Downloaded 378 times
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    • Site-wide: 116,050
    • In microbiology: 7,433
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    • Site-wide: 181,937
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    • Site-wide: 154,253

Comprehensive assessment of functional effects of commonly used sweeteners on ex vivo human gut microbiome

microbiology more details view paper
  • Downloaded 366 times
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    • Site-wide: 119,459
    • In microbiology: 9,889
  • Year to date:
    • Site-wide: 7,995
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    • Site-wide: 51,235

Identification of a new orthonairovirus associated with human febrile illness in China

microbiology more details view paper
  • Downloaded 361 times
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    • Site-wide: 120,895
    • In microbiology: 8,282
  • Year to date:
    • Site-wide: 98,509
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    • Site-wide: 121,888

A novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1

cancer biology more details view paper
  • Downloaded 355 times
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    • Site-wide: 122,316
    • In cancer biology: 3,571
  • Year to date:
    • Site-wide: 59,130
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    • Site-wide: 88,678

CHRAC/ACF Contribute to the Repressive Ground State of Chromatin

molecular biology more details view paper
  • Downloaded 344 times
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    • Site-wide: 125,377
    • In molecular biology: 3,456
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    • Site-wide: 177,947
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    • Site-wide: 173,617

Insights into the drivers of radiating diversification in biodiversity hotspots using Saussurea (Asteraceae) as a case

evolutionary biology more details view paper
  • Downloaded 338 times
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    • Site-wide: 127,257
    • In evolutionary biology: 6,174
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    • Site-wide: 73,201
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    • Site-wide: 56,216

Plastome phylogenomic study of Gentianeae (Gentianaceae): widespread gene tree discordance and its association with evolutionary rate heterogeneity of plastid genes

evolutionary biology more details view paper
  • Downloaded 298 times
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    • Site-wide: 139,042
    • In evolutionary biology: 6,327
  • Year to date:
    • Site-wide: 146,241
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    • Site-wide: 121,630

NAD metabolism modulates mitochondrial function and inflammation and prevents progression of diabetic kidney disease

pathology more details view paper
  • Downloaded 296 times
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    • Site-wide: 139,617
    • In pathology: 857
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Revealing Protein-Level Functional Redundancy in the Human Gut Microbiome using Ultra-deep Metaproteomics

systems biology more details view paper
  • Downloaded 292 times
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    • Site-wide: 140,634
    • In systems biology: 2,945
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    • Site-wide: 75,575
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    • Site-wide: 53,408

Flotillin-2 regulates EGFR activation, degradation, and cancer growth

cancer biology more details view paper
  • Downloaded 288 times
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    • Site-wide: 142,048
    • In cancer biology: None
  • Year to date:
    • Site-wide: 11,487
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Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection

microbiology more details view paper
  • Downloaded 266 times
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    • Site-wide: 148,355
    • In microbiology: None
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    • Site-wide: 13,014
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MetaProClust-MS1: A tool for clustering metaproteomes using rapid MS1 profiling

bioinformatics more details view paper
  • Downloaded 224 times
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    • Site-wide: 160,571
    • In bioinformatics: 11,905
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    • Site-wide: 94,457
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Parvalbumin interneurons in the nucleus accumbens regulate impairment of risk avoidance in DISC1 transgenic mice

neuroscience more details view paper
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    • Site-wide: 162,110
    • In neuroscience: 22,713
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Understanding of the 2-oxoglutarate dehydrogenase and 2-oxoadipate dehydrogenase assembly with the E2o core relevant to a hybrid complex formation

biochemistry more details view paper
  • Downloaded 208 times
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    • Site-wide: 164,751
    • In biochemistry: 4,864
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    • Site-wide: 99,291

Exploring the microbiome-wide lysine acetylation, succinylation and propionylation in human gut microbiota

microbiology more details view paper
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    • Site-wide: 165,393
    • In microbiology: 11,530
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Elevated colonic microbiota-associated paucimannosidic and truncated N-glycans in pediatric ulcerative colitis

systems biology more details view paper
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    • Site-wide: 172,447
    • In systems biology: 3,279
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Evaluating live microbiota biobanking using an ex vivo microbiome assay and metaproteomics

microbiology more details view paper
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    • Site-wide: 174,406
    • In microbiology: 12,791
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Examining the effects of an anti-Salmonella bacteriophage preparation, BAFASAL, on ex vivo human gut microbiome composition and function using a multi-omics approach

microbiology more details view paper
  • Downloaded 161 times
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    • Site-wide: 175,998
    • In microbiology: 12,499
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    • Site-wide: 165,507
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    • Site-wide: 136,369

Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite

immunology more details view paper
  • Downloaded 108 times
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    • Site-wide: 184,850
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