Author: Lei Zhang

Downloads per author, site-wide

Preprints

Morphologic Classification and Automatic Nugent Scoring of Bacterial Vaginosis by Deep Neural Networks

No bioRxiv download data for this paper yet.

Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin

• Downloaded 264,187 times
• Download rankings, all-time:
  • Site-wide: 2 out of 84,643
  • In microbiology: 1 out of 7,191
• Year to date:
  • Site-wide: 2 out of 84,643
• Since beginning of last month:
  • Site-wide: 11 out of 84,643

Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China

• Downloaded 15,448 times
• Download rankings, all-time:
  • Site-wide: 107 out of 84,643
  • In microbiology: 29 out of 7,191
• Year to date:
  • Site-wide: 46 out of 84,643
• Since beginning of last month:
  • Site-wide: 260 out of 84,643

Variability in the analysis of a single neuroimaging dataset by many teams

• Downloaded 4,945 times
• Download rankings, all-time:
  • Site-wide: 699 out of 84,643
  • In neuroscience: 74 out of 15,080
• Year to date:
  • Site-wide: 889 out of 84,643
• Since beginning of last month:
  • Site-wide: 1,618 out of 84,643

Sequence and annotation of 42 cannabis genomes reveals extensive copy number variation in cannabinoid synthesis and pathogen resistance genes

• Downloaded 2,881 times
• Download rankings, all-time:
  • Site-wide: 1,846 out of 84,643
  • In genomics: 374 out of 5,463
• Year to date:
  • Site-wide: 276 out of 84,643
• Since beginning of last month:
  • Site-wide: 1,230 out of 84,643

Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 - implications for microvascular inflammation and hypercoagulopathy in COVID-19 patients

• Downloaded 2,857 times
• Download rankings, all-time:
  • Site-wide: 1,872 out of 84,643
  • In pathology: 11 out of 477
• Year to date:
  • Site-wide: 282 out of 84,643
• Since beginning of last month:
  • Site-wide: 152 out of 84,643

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

• Downloaded 2,092 times
• Download rankings, all-time:
  • Site-wide: 3,172 out of 84,643
  • In biophysics: 80 out of 3,634
• Year to date:
  • Site-wide: 390 out of 84,643
• Since beginning of last month:
  • Site-wide: 457 out of 84,643

Revealing neuro-computational mechanisms of reinforcement learning and decision-making with the hBayesDM package

• Downloaded 2,016 times
• Download rankings, all-time:
  • Site-wide: 3,366 out of 84,643
  • In neuroscience: 484 out of 15,080
• Year to date:
  • Site-wide: 25,682 out of 84,643
• Since beginning of last month:
  • Site-wide: 21,702 out of 84,643

Reversing Glial Scar Back To Neural Tissue Through NeuroD1-Mediated Astrocyte-To-Neuron Conversion

• Downloaded 1,691 times
• Download rankings, all-time:
  • Site-wide: 4,502 out of 84,643
  • In neuroscience: 673 out of 15,080
• Year to date:
  • Site-wide: 10,181 out of 84,643
• Since beginning of last month:
  • Site-wide: 11,305 out of 84,643

TITER: predicting translation initiation sites by deep learning

• Downloaded 1,622 times
• Download rankings, all-time:
  • Site-wide: 4,832 out of 84,643
  • In bioinformatics: 901 out of 8,115
• Year to date:
  • Site-wide: 33,457 out of 84,643
• Since beginning of last month:
  • Site-wide: 21,202 out of 84,643

Reduced Default Mode Network Functional Connectivity in Patients with Recurrent Major Depressive Disorder

• Downloaded 1,348 times
• Download rankings, all-time:
  • Site-wide: 6,596 out of 84,643
  • In neuroscience: 1,007 out of 15,080
• Year to date:
  • Site-wide: 23,410 out of 84,643
• Since beginning of last month:
  • Site-wide: 23,825 out of 84,643

High-depth resequencing reveals hybrid population and insecticide resistance characteristics of fall armyworm (Spodoptera frugiperda) invading China

• Downloaded 1,028 times
• Download rankings, all-time:
  • Site-wide: 10,315 out of 84,643
  • In genomics: 1,494 out of 5,463
• Year to date:
  • Site-wide: 3,206 out of 84,643
• Since beginning of last month:
  • Site-wide: 5,501 out of 84,643

A brain network supporting social influences in human decision-making

• Downloaded 994 times
• Download rankings, all-time:
  • Site-wide: 10,877 out of 84,643
  • In neuroscience: 1,707 out of 15,080
• Year to date:
  • Site-wide: 4,542 out of 84,643
• Since beginning of last month:
  • Site-wide: 3,484 out of 84,643

DeepHINT: Understanding HIV-1 integration via deep learning with attention

• Downloaded 858 times
• Download rankings, all-time:
  • Site-wide: 13,686 out of 84,643
  • In bioinformatics: 2,166 out of 8,115
• Year to date:
  • Site-wide: 15,758 out of 84,643
• Since beginning of last month:
  • Site-wide: 50,679 out of 84,643

SCCNV: a software tool for identifying copy number variation from single-cell whole-genome sequencing

• Downloaded 680 times
• Download rankings, all-time:
  • Site-wide: 19,426 out of 84,643
  • In bioinformatics: 2,867 out of 8,115
• Year to date:
  • Site-wide: 26,994 out of 84,643
• Since beginning of last month:
  • Site-wide: 32,548 out of 84,643

Generating Templates and Growth Charts for School-Aged Brain Development

• Downloaded 648 times
• Download rankings, all-time:
  • Site-wide: 20,882 out of 84,643
  • In neuroscience: 3,481 out of 15,080
• Year to date:
  • Site-wide: 20,974 out of 84,643
• Since beginning of last month:
  • Site-wide: 19,746 out of 84,643

Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria

• Downloaded 565 times
• Download rankings, all-time:
  • Site-wide: 25,317 out of 84,643
  • In biochemistry: 663 out of 2,749
• Year to date:
  • Site-wide: 5,966 out of 84,643
• Since beginning of last month:
  • Site-wide: 9,605 out of 84,643

Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

• Downloaded 545 times
• Download rankings, all-time:
  • Site-wide: 26,421 out of 84,643
  • In genomics: 2,815 out of 5,463
• Year to date:
  • Site-wide: 73,872 out of 84,643
• Since beginning of last month:
  • Site-wide: 67,192 out of 84,643

Multilayered N-glycoproteomics reveals impaired N-glycosylation promoting Alzheimer's disease

• Downloaded 510 times
• Download rankings, all-time:
  • Site-wide: 28,750 out of 84,643
  • In systems biology: 828 out of 2,233
• Year to date:
  • Site-wide: 21,007 out of 84,643
• Since beginning of last month:
  • Site-wide: 17,743 out of 84,643

AutoGenome: An AutoML Tool for Genomic Research

• Downloaded 499 times
• Download rankings, all-time:
  • Site-wide: 29,542 out of 84,643
  • In genomics: 3,020 out of 5,463
• Year to date:
  • Site-wide: 7,126 out of 84,643
• Since beginning of last month:
  • Site-wide: 7,719 out of 84,643

HIV-1 Envelope and MPER antibody structures in lipid assemblies

• Downloaded 489 times
• Download rankings, all-time:
  • Site-wide: 30,260 out of 84,643
  • In immunology: 706 out of 2,372
• Year to date:
  • Site-wide: 9,445 out of 84,643
• Since beginning of last month:
  • Site-wide: 11,321 out of 84,643

Functional Analysis of FRIGIDA Using Naturally Occurring Variation in Arabidopsis thaliana

• Downloaded 453 times
• Download rankings, all-time:
  • Site-wide: 33,189 out of 84,643
  • In plant biology: 910 out of 2,588
• Year to date:
  • Site-wide: 46,460 out of 84,643
• Since beginning of last month:
  • Site-wide: 62,150 out of 84,643

Single-cell whole-genome sequencing reveals mutational landscapes of DNA mismatch repair deficiency in mouse primary fibroblasts

• Downloaded 446 times
• Download rankings, all-time:
  • Site-wide: 33,757 out of 84,643
  • In genomics: 3,292 out of 5,463
• Year to date:
  • Site-wide: 32,445 out of 84,643
• Since beginning of last month:
  • Site-wide: 38,751 out of 84,643

Gene editing of the multi-copy H2A.B gene family by a single pair of TALENS

• Downloaded 428 times
• Download rankings, all-time:
  • Site-wide: 35,433 out of 84,643
  • In genomics: 3,400 out of 5,463
• Year to date:
  • Site-wide: 80,150 out of 84,643
• Since beginning of last month:
  • Site-wide: 76,303 out of 84,643

Reconstruction of cell spatial organization based on ligand-receptor mediated self-assembly

• Downloaded 401 times
• Download rankings, all-time:
  • Site-wide: 38,107 out of 84,643
  • In bioinformatics: 4,671 out of 8,115
• Year to date:
  • Site-wide: 4,015 out of 84,643
• Since beginning of last month:
  • Site-wide: 5,291 out of 84,643

Dissecting the dilemma between in vitro and in vivo drug screening: treating HepG2 cells with Artesunate as a model

• Downloaded 381 times
• Download rankings, all-time:
  • Site-wide: 40,171 out of 84,643
  • In cell biology: 1,972 out of 4,295
• Year to date:
  • Site-wide: 28,045 out of 84,643
• Since beginning of last month:
  • Site-wide: 26,036 out of 84,643

Spontaneous retrotranspositions in normal tissues are rare and associated with cell-type-specific differentiation

• Downloaded 364 times
• Download rankings, all-time:
  • Site-wide: 41,997 out of 84,643
  • In genomics: 3,783 out of 5,463
• Year to date:
  • Site-wide: 68,240 out of 84,643
• Since beginning of last month:
  • Site-wide: 61,474 out of 84,643

Regeneration of dorsal spinal cord neurons after injury via in situ NeuroD1-mediated astrocyte-to-neuron conversion

• Downloaded 353 times
• Download rankings, all-time:
  • Site-wide: 43,304 out of 84,643
  • In neuroscience: 7,557 out of 15,080
• Year to date:
  • Site-wide: 15,661 out of 84,643
• Since beginning of last month:
  • Site-wide: 19,373 out of 84,643

Rational design of hepatitis C virus E2 core nanoparticle vaccines

• Downloaded 345 times
• Download rankings, all-time:
  • Site-wide: 44,203 out of 84,643
  • In microbiology: 3,069 out of 7,191
• Year to date:
  • Site-wide: 22,786 out of 84,643
• Since beginning of last month:
  • Site-wide: 18,132 out of 84,643

Genome-wide association study of appendicular lean mass in UK Biobank cohort

• Downloaded 333 times
• Download rankings, all-time:
  • Site-wide: 45,714 out of 84,643
  • In genetics: 2,658 out of 4,444
• Year to date:
  • Site-wide: 36,041 out of 84,643
• Since beginning of last month:
  • Site-wide: 31,154 out of 84,643

Chemistry of cation hydration and conduction in a skeletal muscle ryanodine receptor

• Downloaded 314 times
• Download rankings, all-time:
  • Site-wide: 48,197 out of 84,643
  • In biochemistry: 1,412 out of 2,749
• Year to date:
  • Site-wide: 36,247 out of 84,643
• Since beginning of last month:
  • Site-wide: 32,137 out of 84,643

miRNAs play important roles in aroma weakening during the shelf life of 'Nanguo' pear after cold storage

• Downloaded 302 times
• Download rankings, all-time:
  • Site-wide: 49,935 out of 84,643
  • In molecular biology: 1,600 out of 2,845
• Year to date:
  • Site-wide: 66,404 out of 84,643
• Since beginning of last month:
  • Site-wide: 64,757 out of 84,643

A general model to explain repeated turnovers of sex determination in the Salicaceae

• Downloaded 302 times
• Download rankings, all-time:
  • Site-wide: 49,895 out of 84,643
  • In genomics: 4,160 out of 5,463
• Year to date:
  • Site-wide: 6,233 out of 84,643
• Since beginning of last month:
  • Site-wide: 2,004 out of 84,643

Amorphous nickel titanium alloy film: a new choice for cryo electron microscopy sample preparation

• Downloaded 274 times
• Download rankings, all-time:
  • Site-wide: 53,897 out of 84,643
  • In biophysics: 2,272 out of 3,634
• Year to date:
  • Site-wide: 7,284 out of 84,643
• Since beginning of last month:
  • Site-wide: 12,408 out of 84,643

Effects of sugars and lipids on the growth and development of Caenorhabditis elegans

• Downloaded 260 times
• Download rankings, all-time:
  • Site-wide: 55,982 out of 84,643
  • In genetics: 3,169 out of 4,444
• Year to date:
  • Site-wide: 45,212 out of 84,643
• Since beginning of last month:
  • Site-wide: 48,367 out of 84,643

Characterization of fluorescent proteins with intramolecular photostabilization

• Downloaded 245 times
• Download rankings, all-time:
  • Site-wide: 58,301 out of 84,643
  • In biophysics: 2,476 out of 3,634
• Year to date:
  • Site-wide: 8,670 out of 84,643
• Since beginning of last month:
  • Site-wide: 28,893 out of 84,643

An optimized 16S rRNA sequencing protocol for vaginal microbiome to avoid biased abundance estimation

• Downloaded 243 times
• Download rankings, all-time:
  • Site-wide: 58,573 out of 84,643
  • In microbiology: 4,415 out of 7,191
• Year to date:
  • Site-wide: 13,734 out of 84,643
• Since beginning of last month:
  • Site-wide: 15,676 out of 84,643

The mechanosensitive Piezo1 orchestrating angiogenesis is essential in bone fracture repair

• Downloaded 241 times
• Download rankings, all-time:
  • Site-wide: 58,907 out of 84,643
  • In systems biology: 1,712 out of 2,233
• Year to date:
  • Site-wide: 17,953 out of 84,643
• Since beginning of last month:
  • Site-wide: 49,537 out of 84,643

Early detection of retinal alteration by visible and near-infrared optical coherence tomography (vnOCT) in a dexamethasone-induced ocular hypertension mouse model

• Downloaded 233 times
• Download rankings, all-time:
  • Site-wide: 60,130 out of 84,643
  • In bioengineering: 1,176 out of 1,859
• Year to date:
  • Site-wide: 66,070 out of 84,643
• Since beginning of last month:
  • Site-wide: 62,381 out of 84,643

Performance of bitumen coating sheet using biomass pyrolysis oil

• Downloaded 230 times
• Download rankings, all-time:
  • Site-wide: 60,683 out of 84,643
  • In bioengineering: 1,192 out of 1,859
• Year to date:
  • Site-wide: 46,551 out of 84,643
• Since beginning of last month:
  • Site-wide: 49,120 out of 84,643

High-quality de novo genome assembly of Kappaphycus alvarezii based on both PacBio and HiSeq sequencing

• Downloaded 196 times
• Download rankings, all-time:
  • Site-wide: 66,371 out of 84,643
  • In genomics: 4,818 out of 5,463
• Year to date:
  • Site-wide: 12,183 out of 84,643
• Since beginning of last month:
  • Site-wide: 31,700 out of 84,643

AutoOmics: An AutoML Tool for Multi-Omics Research

• Downloaded 172 times
• Download rankings, all-time:
  • Site-wide: 70,265 out of 84,643
  • In bioinformatics: 7,129 out of 8,115
• Year to date:
  • Site-wide: 14,717 out of 84,643
• Since beginning of last month:
  • Site-wide: 4,263 out of 84,643

The CEPR2-mediated phosphorylation of NRT1.2 mainly regulates ABA import in Arabidopsis

• Downloaded 170 times
• Download rankings, all-time:
  • Site-wide: 70,517 out of 84,643
  • In molecular biology: 2,343 out of 2,845
• Year to date:
  • Site-wide: 14,930 out of 84,643
• Since beginning of last month:
  • Site-wide: 36,297 out of 84,643

The Nonequilibrium Mechanism of Noise Enhancer synergizing with Activator in HIV Latency Reactivation

• Downloaded 151 times
• Download rankings, all-time:
  • Site-wide: 73,486 out of 84,643
  • In systems biology: 2,057 out of 2,233
• Year to date:
  • Site-wide: 17,722 out of 84,643
• Since beginning of last month:
  • Site-wide: 31,796 out of 84,643

Mendelian randomization analysis revealed causal effects from gut microbiota to abdominal obesity

• Downloaded 126 times
• Download rankings, all-time:
  • Site-wide: 76,812 out of 84,643
  • In genomics: 5,152 out of 5,463
• Year to date:
  • Site-wide: 22,499 out of 84,643
• Since beginning of last month:
  • Site-wide: 6,637 out of 84,643

CNSA: a data repository for archiving omics data

• Downloaded 108 times
• Download rankings, all-time:
  • Site-wide: 78,690 out of 84,643
  • In genomics: 5,219 out of 5,463
• Year to date:
  • Site-wide: 27,287 out of 84,643
• Since beginning of last month:
  • Site-wide: 8,174 out of 84,643

Dix-seq: An integrated pipeline for fast amplicon data analysis

• Downloaded 75 times
• Download rankings, all-time:
  • Site-wide: 81,151 out of 84,643
  • In bioinformatics: 7,848 out of 8,115
• Year to date:
  • Site-wide: 41,189 out of 84,643
• Since beginning of last month:
  • Site-wide: 13,256 out of 84,643