Author: Yang Li

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Preprints

Sleep Need, the Key Regulator of Sleep Homeostasis, Is Indicated and Controlled by Phosphorylation of Threonine 221 in Salt Inducible Kinase 3

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The BNT162b2 mRNA vaccine against SARS-CoV-2 reprograms both adaptive and innate immune responses

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Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19

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SnapATAC: A Comprehensive Analysis Package for Single Cell ATAC-seq

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Global profiling of SARS-CoV-2 specific IgG/ IgM responses of convalescents using a proteome microarray

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A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas

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Optimizing diagnostic strategy for novel coronavirus pneumonia, a multi-center study in Eastern China

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Suppressive myeloid cells are a hallmark of severe COVID-19

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Binary and analog variation of synapses between cortical pyramidal neurons

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The cross-sectional study of hospitalized coronavirus disease 2019 patients in Xiangyang, Hubei province

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A descriptive study of the impact of diseases control and prevention on the epidemics dynamics and clinical features of SARS-CoV-2 outbreak in Shanghai, lessons learned for metropolis epidemics prevention

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A single dose SARS-CoV-2 simulating particle vaccine induces potent neutralizing activities

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Multiscale and multimodal reconstruction of cortical structure and function

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CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

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Antibody dynamics to SARS-CoV-2 in Asymptomatic and Mild COVID-19 patients

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Cell specific eQTL analysis without sorting cells

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Chandelier cell anatomy and function reveal a variably distributed but common signal

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GeNets: A unified web platform for network-based analyses of genomic data

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Allele-Specific Quantification of Structural Variations in Cancer Genomes

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Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

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An epigenetic landscape governs early fate decision in cellular aging

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Preliminary evaluation of the safety and efficacy of oral human antimicrobial peptide LL-37 in the treatment of patients of COVID-19, a small-scale, single-arm, exploratory safety study

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Identification of PDE6D as a potential target of sorafenib via PROTAC technology

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Natural Variation of OsLG3 Controls Drought Stress Tolerance in Rice by Inducing ROS Scavenging

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  • Site-wide: 25,932
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Antibody binding epitope Mapping (AbMap) of hundred antibodies in a single run

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  • Site-wide: 33,184

RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

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  • Site-wide: 14,153

Induction of trained immunity by influenza vaccination - impact on COVID-19

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  • Site-wide: 29,776
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Linear epitope landscape of SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients

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  • Site-wide: 31,731
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The N-cadherin interactome in primary cardiomyocytes as defined by quantitative proximity proteomics.

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Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients

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Biological variation in the sizes, shapes and locations of visual cortical areas in the mouse

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  • Site-wide: 34,808
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An Array of 60,000 Antibodies for Proteome-Scale Antibody Generation and Target Discovery

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Multi-generational silencing dynamics control cell aging

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  • Site-wide: 39,305
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Recurrently deregulated lncRNAs associated with HCC tumorigenesis and metastasis revealed by genomic, epigenomic and transcriptomic profiling in paired primary tumor and PVTT samples

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Novel mode of filament formation in UPA-promoted CARD8 and NLRP1 Inflammasomes

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Electrospun Ag-doped SnO2 hollow nanofibers with high antibacterial activity

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Cycloserine for Treatment of Multidrug-Resistant Tuberculosis in China: A Retrospective Observational Study

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Gender differences in attitudes toward death among Chinese university students: A survey in hunan and Heilongjiang province

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From Community Acquired Pneumonia to COVID-19: A Deep Learning Based Method for Quantitative Analysis of COVID-19 on thick-section CT Scans

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Epigenetic Reprogramming of Tissue-Specific Transcription Promotes Metastasis

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Vinculin anchors contractile actin to the cardiomyocyte adherens junction

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Spatiotemporal functional organization of excitatory synaptic inputs onto macaque V1 neurons

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High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers

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Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity

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The genetic risk for COVID-19 severity is associated with defective innate immune responses

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Ultra-fast and accurate motif finding in large ChIP-seq datasets reveals transcription factor binding patterns

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Progressive and accurate assembly of multi-domain protein structures from cryo-EM density maps

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Systematic profiling of SARS-CoV-2 specific IgG epitopes at single amino acid resolution

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bHLH11 negatively regulates Fe homeostasis by its EAR motifs recruiting corepressors in Arabidopsis

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A label-free approach to detect ligand binding to cell surface proteins in real time

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SLFL Genes Participate in the Ubiquitination and Degradation of S-RNase in Self-Compatible Chinese Peach

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Biological network inference from single-cell multi-omics data using heterogeneous graph transformer

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Structural and mechanistic basis for protein glutamylation by the kinase fold

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Systematic evaluation of SARS-CoV-2 spike protein derived peptides for diagnosis of COVID-19 patients

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Deducing high-accuracy protein contact-maps from a triplet of coevolutionary matrices through deep residual convolutional networks

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Variable sensitivity to DNA damaging chemotherapeutic modulated by cell type-dependent bimodal p53 dynamics

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Microplate Assay for Denatured Collagen using Collagen Hybridizing Peptides

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Systematic prioritization of candidate genes in disease loci identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease

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Evolution of cytokine production capacity in ancient and modern European populations

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Cytochrome OmcS is not essential for long-range electron transport in Geobacter sulfurreducens strain KN400

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Spike Protein Targeting "Nano-Glue" that Captures and Promotes SARS-CoV-2 Elimination

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RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases

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FER-LIKE FE DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (OsFIT) interacts with OsIRO2 to regulate iron homeostasis

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Reconstructing species evolutionary trees using the numerical features of microRNA

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In-House Forecasting of Crop Latitude Adaptation through a Daylength-sensing-based Environment Adaptation Simulator (DEAS)

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Evolutionary rate covariation analysis of E-cadherin identifies Raskol as regulator of cell adhesion and actin dynamics in Drosophila

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Rapid detection of cytochrome cd1-containing nitrite reductase encoding gene nirS with loop-mediated isothermal amplification assay

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Topographic Guidance in Melt-Electrowritten Tubular Scaffolds Enhances Engineered Kidney Tubule Performance

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PD-L1 upregulation by IFN-α/γ-mediated Stat1 suppresses anti-HBV T cell response

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Exploration of target spaces in the human genome for protein and peptide drugs

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MpsLDA-ProSVM: predicting multi-label protein subcellular localization by wMLDAe dimensionality reduction and ProSVM classifier

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Protein Surface Printer for Exploring Protein Domains

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A universal approach for integrating super large-scale single-cell transcriptomes by exploring gene rankings

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Discovering Differences and Similarities among Species Based on Numeric Features of microRNAs

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Age-induced P-bodies become detrimental and shorten the lifespan of yeast

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Discovery Function Labels Based On Numerical Features Of MicroRNA Found In Plant

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A combined microphysiological-computational omics approach in dietary protein evaluation

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COVID-ONE-humoral immune: The One-stop Database for COVID-19-specific Antibody Responses and Clinical Parameters

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Collagen induced inflammations

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Reverse-transcription recombinase-aided amplification assay for H5 subtype avian influenza virus

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A new strategy for selection of crop cultivated varieties based on yield factors driving and meteorological prediction

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HAMdetector: A Bayesian regression model that integrates information to detect HLA-associated mutations

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Molecular mechanism of the anti-lung cancer effect of Jin Ning Fang based on network pharmacology and experimental verification

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MiR-339-3p aggravates rat vascular inflammation induced by AT1R autoantibodies by down-regulating BKα protein expression

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COVID-ONE-humoral immune: The One-stop Database for COVID-19-specific Antibody Responses and Clinical Parameters

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Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell self-renewal, differentiation and survival

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Effects of electroacupuncture on the expression of hypothalamic neuropeptide Y and ghrelin in pubertal rats with polycystic ovary syndrome

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