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Author: Andrew Owen

Rankings

  • All-time downloads: 39,358 (rank: 6,224 )
  • Categories:
    • genetics: 299 (rank: 40,011 (tie) )
    • immunology: 1,478 (rank: 10,447 (tie) )
    • infectious diseases: 5,245 (rank: 11,487 )
    • microbiology: 15,808 (rank: 1,386 (tie) )
    • pathology: 1,182 (rank: 1,413 (tie) )
    • pharmacology and therapeutics: 9,585 (rank: 43 (tie) )
    • pharmacology and toxicology: 2,059 (rank: 671 (tie) )
    • respiratory medicine: 601 (rank: 1,736 (tie) )

Downloads per author, site-wide

Preprints

SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19

microbiology more details view paper
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    • Site-wide: 2,153
    • In microbiology: 192
  • Year to date:
    • Site-wide: 199
  • Since beginning of last month:
    • Site-wide: 3,234

Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate target site concentrations derived from their established human pharmacokinetics

pharmacology and therapeutics more details view paper
  • Downloaded 4,850 times
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    • Site-wide: 3,303
    • In pharmacology and therapeutics: 9
  • Year to date:
    • Site-wide: 29,285
  • Since beginning of last month:
    • Site-wide: 54,926

Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a phase 1, dose-escalating, randomised controlled study

pharmacology and therapeutics more details view paper
  • Downloaded 4,458 times
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    • Site-wide: 3,710
    • In pharmacology and therapeutics: 11
  • Year to date:
    • Site-wide: 2,170
  • Since beginning of last month:
    • Site-wide: 6,070

Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2

microbiology more details view paper
  • Downloaded 3,855 times
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    • Site-wide: 4,537
    • In microbiology: 294
  • Year to date:
    • Site-wide: 25,478
  • Since beginning of last month:
    • Site-wide: 50,777

Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis

infectious diseases more details view paper
  • Downloaded 3,295 times
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    • Site-wide: 5,705
    • In infectious diseases: 1,085
  • Year to date:
    • Site-wide: 42,055
  • Since beginning of last month:
    • Site-wide: 38,721

The in vitro antiviral activity of the anti-hepatitis C virus (HCV) drugs daclatasvir and sofosbuvir against SARS-CoV-2

microbiology more details view paper
  • Downloaded 2,696 times
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    • Site-wide: 7,615
    • In microbiology: 450
  • Year to date:
    • Site-wide: 46,118
  • Since beginning of last month:
    • Site-wide: 43,275

Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19.

microbiology more details view paper
  • Downloaded 1,898 times
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    • Site-wide: 12,834
    • In microbiology: 758
  • Year to date:
    • Site-wide: 23,609
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    • Site-wide: 49,275

Single-dose immunisation with a multimerised SARS-CoV-2 receptor binding domain (RBD) induces an enhanced and protective response in mice

immunology more details view paper
  • Downloaded 1,513 times
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    • Site-wide: 18,093
    • In immunology: 617
  • Year to date:
    • Site-wide: 66,114
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    • Site-wide: 104,273

Neuroinvasion and neurotropism by SARS-CoV-2 variants in the K18-hACE2 mouse

pathology more details view paper
  • Downloaded 1,401 times
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    • Site-wide: 20,359
    • In pathology: 106
  • Year to date:
    • Site-wide: 11,655
  • Since beginning of last month:
    • Site-wide: 12,024

Modelling of Systemic versus Pulmonary Chloroquine Exposure in Man for COVID-19 Dose Selection

infectious diseases more details view paper
  • Downloaded 1,169 times
  • Download rankings, all-time:
    • Site-wide: 26,948
    • In infectious diseases: 2,510
  • Year to date:
    • Site-wide: 107,680
  • Since beginning of last month:
    • Site-wide: 93,948

Development of a highly sensitive bioanalytical assay for the quantification of favipiravir.

pharmacology and toxicology more details view paper
  • Downloaded 993 times
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    • Site-wide: 34,489
    • In pharmacology and toxicology: 214
  • Year to date:
    • Site-wide: 23,869
  • Since beginning of last month:
    • Site-wide: 15,535

Naturally-acquired immunity in Syrian Golden Hamsters provides protection from re-exposure to emerging heterosubtypic SARS-CoV-2 variants B.1.1.7 and B.1.351

microbiology more details view paper
  • Downloaded 830 times
  • Download rankings, all-time:
    • Site-wide: 44,968
    • In microbiology: 2,603
  • Year to date:
    • Site-wide: 91,341
  • Since beginning of last month:
    • Site-wide: 59,600

Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5'-triphosphate exposure to support posology for SARS-CoV-2

infectious diseases more details view paper
  • Downloaded 798 times
  • Download rankings, all-time:
    • Site-wide: 47,609
    • In infectious diseases: 3,503
  • Year to date:
    • Site-wide: 38,971
  • Since beginning of last month:
    • Site-wide: 53,133

An open label, adaptive, phase 1 trial of high-dose oral nitazoxanide in healthy volunteers: an antiviral candidate for SARS-CoV-2

pharmacology and therapeutics more details view paper
  • Downloaded 712 times
  • Download rankings, all-time:
    • Site-wide: 55,953
    • In pharmacology and therapeutics: 64
  • Year to date:
    • Site-wide: 68,909
  • Since beginning of last month:
    • Site-wide: 63,825

TITLE: Randomised Controlled Trial of Intravenous Nafamostat Mesylate in COVID pneumonitis: Phase 1b/2a Experimental Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics

respiratory medicine more details view paper
  • Downloaded 669 times
  • Download rankings, all-time:
    • Site-wide: 61,212
    • In respiratory medicine: 135
  • Year to date:
    • Site-wide: 35,859
  • Since beginning of last month:
    • Site-wide: 43,709

Unlike Chloroquine, mefloquine inhibits SARS-CoV-2 infection in physiologically relevant cells and does not induce viral variants.

microbiology more details view paper
  • Downloaded 618 times
  • Download rankings, all-time:
    • Site-wide: 67,882
    • In microbiology: 4,036
  • Year to date:
    • Site-wide: 109,616
  • Since beginning of last month:
    • Site-wide: 102,372

Evaluation of intranasal nafamostat or camostat for SARS-CoV-2 chemoprophylaxis in Syrian golden hamsters

pharmacology and toxicology more details view paper
  • Downloaded 589 times
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    • Site-wide: 72,102
    • In pharmacology and toxicology: 507
  • Year to date:
    • Site-wide: 32,084
  • Since beginning of last month:
    • Site-wide: 26,306

Lack of Ronapreve (REGN-CoV; casirivimab and imdevimab) virological efficacy against the SARS-CoV 2 Omicron variant (B.1.1.529) in K18-hACE2 mice

microbiology more details view paper
  • Downloaded 577 times
  • Download rankings, all-time:
    • Site-wide: 74,098
    • In microbiology: 7,654
  • Year to date:
    • Site-wide: 4,088
  • Since beginning of last month:
    • Site-wide: 29,367

Optimisation and validation of a sensitive bioanalytical method for niclosamide.

pharmacology and toxicology more details view paper
  • Downloaded 526 times
  • Download rankings, all-time:
    • Site-wide: 82,743
    • In pharmacology and toxicology: 590
  • Year to date:
    • Site-wide: 40,790
  • Since beginning of last month:
    • Site-wide: 29,911

N-acetyltransferase 2 genotypes amongst ulu Speaking South Africans and isoniazid / N-acetyl-isoniazid pharmacokinetics during ant-tuberculosis treatment

genetics more details view paper
  • Downloaded 320 times
  • Download rankings, all-time:
    • Site-wide: 132,657
    • In genetics: 4,970
  • Year to date:
    • Site-wide: 121,338
  • Since beginning of last month:
    • Site-wide: 122,805

Efficacy and safety of nitazoxanide combined with ritonavir-boosted atazanavir for the treatment of mild to moderate COVID-19

infectious diseases more details view paper
  • Downloaded 275 times
  • Download rankings, all-time:
    • Site-wide: 145,969
    • In infectious diseases: 6,908
  • Year to date:
    • Site-wide: 12,598
  • Since beginning of last month:
    • Site-wide: 36,136

Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.

pharmacology and toxicology more details view paper
  • Downloaded 274 times
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    • Site-wide: 146,242
    • In pharmacology and toxicology: 1,127
  • Year to date:
    • Site-wide: 91,326
  • Since beginning of last month:
    • Site-wide: 56,745

Early Treatment of Favipiravir in COVID-19 Patients Without Pneumonia: A Multicentre, Open-Labelled, Randomized Control Study

pharmacology and therapeutics more details view paper
  • Downloaded 194 times
  • Download rankings, all-time:
    • Site-wide: 168,461
    • In pharmacology and therapeutics: None
  • Year to date:
    • Site-wide: 21,051
  • Since beginning of last month:
    • Site-wide: 3,104

Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays.

pharmacology and toxicology more details view paper
  • Downloaded 190 times
  • Download rankings, all-time:
    • Site-wide: 169,607
    • In pharmacology and toxicology: None
  • Year to date:
    • Site-wide: 21,685
  • Since beginning of last month:
    • Site-wide: 48,374

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