Author: Jason S McLellan

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Preprints

Anamnestic Humoral Correlates of Immunity Across SARS-CoV-2 Variants of Concern

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Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein

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Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation

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SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma

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Molecular Architecture of Early Disseminationand Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area

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Site-specific analysis of the SARS-CoV-2 glycan shield

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Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies

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LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

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Beyond Shielding: The Roles of Glycans in SARS-CoV-2 Spike Protein

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Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

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Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled, Phase 1/2 Trial

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Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes

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Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates

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Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

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An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

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A glycan gate controls opening of the SARS-CoV-2 spike protein

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Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma

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Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

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Identification of a conserved neutralizing epitope present on spike proteins from all highly pathogenic coronaviruses

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Molecular Architecture of Early Dissemination and Evolution of the SARS-CoV-2 Virus in Metropolitan Houston, Texas

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Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

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Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality

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Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19

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The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes

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Local computational methods to improve the interpretability and analysis of cryo-EM maps

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The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US

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Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking

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Structural basis for HCMV Pentamer recognition by antibodies and neuropilin 2

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Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures

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Potent neutralization of SARS-CoV-2 variants of concern by an antibody with a unique genetic signature and structural mode of spike recognition

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A combination of RBD and NTD neutralizing antibodies limits the generation of SARS-CoV-2 spike neutralization-escape mutants

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Safety and Immunogenicity of An Egg-Based Inactivated Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomized, Placebo-Controlled, Phase 1/2 Trial in Vietnam

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Trimeric SARS-CoV-2 Spike proteins produced from CHO-cells in bioreactors are high-quality antigens

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Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

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Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus

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HCMV glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB protein immunization

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CryoEM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition

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Structural basis for ultrapotent neutralization of human metapneumovirus

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A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus

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