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Author: Jason S McLellan

Rankings

  • All-time downloads: 171,453 (rank: 824 )
  • Categories:
    • biochemistry: 1,521 (rank: 4,544 (tie) )
    • biophysics: 10,744 (rank: 165 )
    • cell biology: 459 (rank: 29,211 (tie) )
    • epidemiology: 1,176 (rank: 11,934 (tie) )
    • genetics: 1,611 (rank: 13,079 (tie) )
    • immunology: 56,102 (rank: 276 )
    • infectious diseases: 5,374 (rank: 11,284 (tie) )
    • microbiology: 72,381 (rank: 246 )
    • pathology: 15,451 (rank: 68 (tie) )
    • synthetic biology: 1,388 (rank: 1,945 (tie) )

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Preprints

Anamnestic Humoral Correlates of Immunity Across SARS-CoV-2 Variants of Concern

immunology more details view paper

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Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein

molecular biology more details view paper

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Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation

microbiology more details view paper
  • Downloaded 35,709 times
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    • Site-wide: 276
    • In microbiology: 25
  • Year to date:
    • Site-wide: 611
  • Since beginning of last month:
    • Site-wide: 2,527

SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma

immunology more details view paper
  • Downloaded 32,403 times
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    • Site-wide: 309
    • In immunology: 18
  • Year to date:
    • Site-wide: 2,482
  • Since beginning of last month:
    • Site-wide: 4,264

Molecular Architecture of Early Disseminationand Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area

pathology more details view paper
  • Downloaded 15,612 times
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    • Site-wide: 722
    • In pathology: 5
  • Year to date:
    • Site-wide: 12,088
  • Since beginning of last month:
    • Site-wide: 11,806

Site-specific analysis of the SARS-CoV-2 glycan shield

microbiology more details view paper
  • Downloaded 12,520 times
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    • Site-wide: 963
    • In microbiology: 92
  • Year to date:
    • Site-wide: 14,723
  • Since beginning of last month:
    • Site-wide: 18,513

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies

microbiology more details view paper
  • Downloaded 11,323 times
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    • Site-wide: 1,094
    • In microbiology: 101
  • Year to date:
    • Site-wide: 37,676
  • Since beginning of last month:
    • Site-wide: 67,707

LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

immunology more details view paper
  • Downloaded 8,315 times
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    • Site-wide: 1,605
    • In immunology: 56
  • Year to date:
    • Site-wide: 4,471
  • Since beginning of last month:
    • Site-wide: 4,037

Beyond Shielding: The Roles of Glycans in SARS-CoV-2 Spike Protein

biophysics more details view paper
  • Downloaded 6,570 times
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    • Site-wide: 2,196
    • In biophysics: 21
  • Year to date:
    • Site-wide: 20,236
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    • Site-wide: 23,583

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

microbiology more details view paper
  • Downloaded 6,096 times
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    • Site-wide: 2,426
    • In microbiology: 187
  • Year to date:
    • Site-wide: 76,564
  • Since beginning of last month:
    • Site-wide: 112,444

Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled, Phase 1/2 Trial

infectious diseases more details view paper
  • Downloaded 5,216 times
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    • Site-wide: 3,003
    • In infectious diseases: 757
  • Year to date:
    • Site-wide: 3,850
  • Since beginning of last month:
    • Site-wide: 8,042

Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes

microbiology more details view paper
  • Downloaded 5,125 times
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    • Site-wide: 3,079
    • In microbiology: 227
  • Year to date:
    • Site-wide: 12,992
  • Since beginning of last month:
    • Site-wide: 12,404

Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates

immunology more details view paper
  • Downloaded 2,943 times
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    • Site-wide: 6,706
    • In immunology: 266
  • Year to date:
    • Site-wide: 8,956
  • Since beginning of last month:
    • Site-wide: 9,182

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

immunology more details view paper
  • Downloaded 2,648 times
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    • Site-wide: 7,819
    • In immunology: 278
  • Year to date:
    • Site-wide: 58,596
  • Since beginning of last month:
    • Site-wide: 84,604

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

immunology more details view paper
  • Downloaded 2,140 times
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    • Site-wide: 10,696
    • In immunology: 387
  • Year to date:
    • Site-wide: 24,174
  • Since beginning of last month:
    • Site-wide: 19,853

A glycan gate controls opening of the SARS-CoV-2 spike protein

biophysics more details view paper
  • Downloaded 1,882 times
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    • Site-wide: 12,984
    • In biophysics: 285
  • Year to date:
    • Site-wide: 36,047
  • Since beginning of last month:
    • Site-wide: 27,872

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma

immunology more details view paper
  • Downloaded 1,830 times
  • Download rankings, all-time:
    • Site-wide: 13,506
    • In immunology: 467
  • Year to date:
    • Site-wide: 33,526
  • Since beginning of last month:
    • Site-wide: 52,728

Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

immunology more details view paper
  • Downloaded 1,820 times
  • Download rankings, all-time:
    • Site-wide: 13,615
    • In immunology: 500
  • Year to date:
    • Site-wide: 21,775
  • Since beginning of last month:
    • Site-wide: 44,299

Identification of a conserved neutralizing epitope present on spike proteins from all highly pathogenic coronaviruses

biochemistry more details view paper
  • Downloaded 1,741 times
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    • Site-wide: 14,572
    • In biochemistry: 348
  • Year to date:
    • Site-wide: 8,735
  • Since beginning of last month:
    • Site-wide: 9,197

Molecular Architecture of Early Dissemination and Evolution of the SARS-CoV-2 Virus in Metropolitan Houston, Texas

genetics more details view paper
  • Downloaded 1,651 times
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    • Site-wide: 15,743
    • In genetics: 635
  • Year to date:
    • Site-wide: 87,045
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    • Site-wide: 85,084

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

immunology more details view paper
  • Downloaded 1,619 times
  • Download rankings, all-time:
    • Site-wide: 16,207
    • In immunology: 584
  • Year to date:
    • Site-wide: 29,594
  • Since beginning of last month:
    • Site-wide: 47,694

Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality

synthetic biology more details view paper
  • Downloaded 1,530 times
  • Download rankings, all-time:
    • Site-wide: 17,732
    • In synthetic biology: 232
  • Year to date:
    • Site-wide: 20,923
  • Since beginning of last month:
    • Site-wide: 26,997

Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19

immunology more details view paper
  • Downloaded 1,473 times
  • Download rankings, all-time:
    • Site-wide: 18,776
    • In immunology: 780
  • Year to date:
    • Site-wide: 12,474
  • Since beginning of last month:
    • Site-wide: 20,535

The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes

biophysics more details view paper
  • Downloaded 1,346 times
  • Download rankings, all-time:
    • Site-wide: 21,591
    • In biophysics: 529
  • Year to date:
    • Site-wide: 20,413
  • Since beginning of last month:
    • Site-wide: 56,201

Local computational methods to improve the interpretability and analysis of cryo-EM maps

biophysics more details view paper
  • Downloaded 1,268 times
  • Download rankings, all-time:
    • Site-wide: 23,732
    • In biophysics: 590
  • Year to date:
    • Site-wide: 71,891
  • Since beginning of last month:
    • Site-wide: 61,953

The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US

epidemiology more details view paper
  • Downloaded 1,263 times
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    • Site-wide: 23,855
    • In epidemiology: 1,479
  • Year to date:
    • Site-wide: 33,951
  • Since beginning of last month:
    • Site-wide: 18,795

Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking

immunology more details view paper
  • Downloaded 1,053 times
  • Download rankings, all-time:
    • Site-wide: 31,470
    • In immunology: 1,196
  • Year to date:
    • Site-wide: 14,836
  • Since beginning of last month:
    • Site-wide: 39,013

Structural basis for HCMV Pentamer recognition by antibodies and neuropilin 2

microbiology more details view paper
  • Downloaded 955 times
  • Download rankings, all-time:
    • Site-wide: 36,429
    • In microbiology: 2,081
  • Year to date:
    • Site-wide: 69,772
  • Since beginning of last month:
    • Site-wide: 166,535

Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures

microbiology more details view paper
  • Downloaded 930 times
  • Download rankings, all-time:
    • Site-wide: 37,958
    • In microbiology: 2,128
  • Year to date:
    • Site-wide: 115,601
  • Since beginning of last month:
    • Site-wide: 138,793

Potent neutralization of SARS-CoV-2 variants of concern by an antibody with a unique genetic signature and structural mode of spike recognition

immunology more details view paper
  • Downloaded 847 times
  • Download rankings, all-time:
    • Site-wide: 43,585
    • In immunology: 1,379
  • Year to date:
    • Site-wide: 82,855
  • Since beginning of last month:
    • Site-wide: 88,998

A combination of RBD and NTD neutralizing antibodies limits the generation of SARS-CoV-2 spike neutralization-escape mutants

microbiology more details view paper
  • Downloaded 635 times
  • Download rankings, all-time:
    • Site-wide: 65,378
    • In microbiology: 4,214
  • Year to date:
    • Site-wide: 47,384
  • Since beginning of last month:
    • Site-wide: 52,816

Safety and Immunogenicity of An Egg-Based Inactivated Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomized, Placebo-Controlled, Phase 1/2 Trial in Vietnam

infectious diseases more details view paper
  • Downloaded 511 times
  • Download rankings, all-time:
    • Site-wide: 85,533
    • In infectious diseases: 4,815
  • Year to date:
    • Site-wide: 4,811
  • Since beginning of last month:
    • Site-wide: 47,813

Trimeric SARS-CoV-2 Spike proteins produced from CHO-cells in bioreactors are high-quality antigens

cell biology more details view paper
  • Downloaded 489 times
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    • Site-wide: 89,765
    • In cell biology: 3,966
  • Year to date:
    • Site-wide: 109,672
  • Since beginning of last month:
    • Site-wide: 65,488

Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

immunology more details view paper
  • Downloaded 472 times
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    • Site-wide: 93,533
    • In immunology: 2,746
  • Year to date:
    • Site-wide: 119,224
  • Since beginning of last month:
    • Site-wide: 120,715

Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus

immunology more details view paper
  • Downloaded 436 times
  • Download rankings, all-time:
    • Site-wide: 101,739
    • In immunology: None
  • Year to date:
    • Site-wide: 6,128
  • Since beginning of last month:
    • Site-wide: 6,366

HCMV glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB protein immunization

immunology more details view paper
  • Downloaded 362 times
  • Download rankings, all-time:
    • Site-wide: 120,553
    • In immunology: 3,481
  • Year to date:
    • Site-wide: 152,064
  • Since beginning of last month:
    • Site-wide: 101,986

CryoEM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition

microbiology more details view paper
  • Downloaded 317 times
  • Download rankings, all-time:
    • Site-wide: 133,290
    • In microbiology: 10,084
  • Year to date:
    • Site-wide: 40,526
  • Since beginning of last month:
    • Site-wide: 69,000

Structural basis for ultrapotent neutralization of human metapneumovirus

immunology more details view paper
  • Downloaded 236 times
  • Download rankings, all-time:
    • Site-wide: 157,018
    • In immunology: None
  • Year to date:
    • Site-wide: 15,507
  • Since beginning of last month:
    • Site-wide: 22,305

A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus

microbiology more details view paper
  • Downloaded 167 times
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    • Site-wide: 174,585
    • In microbiology: 13,239
  • Year to date:
    • Site-wide: 25,221
  • Since beginning of last month:
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