Author: Alexander G Bick

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Preprints

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

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Deep learning enables genetic analysis of the human thoracic aorta

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  • In genomics: 938
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  • Site-wide: 33,522

Clonal hematopoiesis is driven by aberrant activation of TCL1A

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  • In genetics: 913
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Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

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  • Site-wide: 15,132
  • In genetic and genomic medicine: 88
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Clonal hematopoiesis is associated with protection from Alzheimer's disease

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  • Site-wide: 17,916
  • In hematology: 24
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Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology

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  • In genetics: 795
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Clonal hematopoiesis in sickle cell disease

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  • Site-wide: 24,299
  • In hematology: 21
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Prevalence and clinical importance of titin truncating variants in adults without known congestive heart failure

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  • In cardiovascular medicine: 59
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Analysis of cardiac magnetic resonance imaging traits in 29,000 individuals reveals shared genetic basis with dilated cardiomyopathy

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  • In genomics: 2,775
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Increased CHIP Prevalence Amongst People Living with HIV

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  • In genetic and genomic medicine: 240
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Bidirectional Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of intermediate potential

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  • In genetic and genomic medicine: 353
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  • Site-wide: 22,333
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TP53-mediated clonal hematopoiesis confers increased risk for incident peripheral artery disease

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  • In genetic and genomic medicine: 509
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  • Site-wide: 28,945

Cost effective sequencing enables longitudinal profiling of clonal hematopoiesis

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  • In genetic and genomic medicine: 397
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  • Site-wide: 6,303
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Multi-ancestry Genome-wide Association Study of Varicose Veins Reveals Polygenic Architecture, Genetic Overlap with Arterial and Venous Disease, and Novel Therapeutic Opportunities

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  • In cardiovascular medicine: 588
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Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs

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  • In health informatics: 836
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