Author: Isabelle Leclerc

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Preprints

Mitofusins Mfn1 and Mfn2 are required in the β-cell to preserve mitochondrial architecture and insulin secretion

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The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis

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Vertical sleeve gastrectomy lowers kidney SGLT2 expression in the mouse

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The mitochondrial Ca2+ uniporter MCU is required for normal glucose-stimulated insulin secretion in vitro and in vivo

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Intravital imaging of islet Ca2+ dynamics reveals enhanced β cell connectivity after bariatric surgery in mice

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Sorcin stimulates Activation Transcription Factor 6α (ATF6) transcriptional activity

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Reduced expression of TCF7L2 in adipocyte impairs glucose tolerance associated with decreased insulin secretion, incretins levels and lipid metabolism dysregulation in male mice

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Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

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Bariatric surgery normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice

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The long non-coding RNA Pax6os1/PAX6-AS1 modulates pancreatic β-cell identity and function.

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