Author: Aaron Leong

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Preprints

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

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  • Site-wide: 11,874
  • In genetic and genomic medicine: 54
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  • Site-wide: 5,826
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  • Site-wide: 5,711

Cardiometabolic Risk Factors for COVID-19 Susceptibility and Severity: A Mendelian Randomization Analysis

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  • Site-wide: 13,170
  • In epidemiology: 959
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  • Site-wide: 8,802
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  • Site-wide: 15,674

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 21,885
  • In genetics: 956
• Year to date:
  • Site-wide: 13,348
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  • Site-wide: 80,528

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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  • Site-wide: 25,554
  • In genetics: 1,121
• Year to date:
  • Site-wide: 30,207
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  • Site-wide: 65,273

The impact of non-additive genetic associations on age-related complex diseases.

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  • Site-wide: 33,332
  • In genomics: 2,800
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  • Site-wide: 47,010
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  • Site-wide: 142,792

Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler

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  • Site-wide: 48,687
  • In genomics: 3,718
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  • Site-wide: 9,671
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  • Site-wide: 4,051

Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

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  • Site-wide: 59,195
  • In genetic and genomic medicine: 281
• Year to date:
  • Site-wide: 24,097
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  • Site-wide: 22,587

A combined polygenic score of 21,293 rare and 22 common variants significantly improves diabetes diagnosis based on hemoglobin A1C levels

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  • Site-wide: 84,364
  • In genetic and genomic medicine: 418
• Year to date:
  • Site-wide: 19,608
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  • Site-wide: 1,443

Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine Program.

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  • Site-wide: 86,042
  • In genetics: 3,602
• Year to date:
  • Site-wide: 137,441
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  • Site-wide: 153,591

Validation of a Trans-Ancestry Polygenic Risk Score for Type 2 Diabetes in Diverse Populations

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  • Site-wide: 102,823
  • In genetic and genomic medicine: 554
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  • Site-wide: 27,166
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  • Site-wide: 16,455

Genome-Wide Association Meta-Analysis Using a Recessive Model Illuminates Genetic Architecture of Type 2 Diabetes

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  • Site-wide: 122,845
  • In endocrinology: 118
• Year to date:
  • Site-wide: 38,704
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  • Site-wide: 55,866

A long noncoding RNA, LOC157273, is the effector transcript at the chromosome 8p23.1-PPP1R3B metabolic traits and type 2 diabetes risk locus

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  • Site-wide: 145,203
  • In genomics: 7,499
• Year to date:
  • Site-wide: 158,611
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  • Site-wide: 159,736