Author: Marguerite R Irvin

Downloads per author, site-wide

Preprints

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

• Downloaded 9,331 times
• Download rankings, all-time:
  • Site-wide: 1,498
  • In genomics: 101
• Year to date:
  • Site-wide: 18,532
• Since beginning of last month:
  • Site-wide: 12,134

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

• Downloaded 3,520 times
• Download rankings, all-time:
  • Site-wide: 5,781
  • In genomics: 538
• Year to date:
  • Site-wide: 140,502
• Since beginning of last month:
  • Site-wide: 30,209

Clonal hematopoiesis is driven by aberrant activation of TCL1A

• Downloaded 2,430 times
• Download rankings, all-time:
  • Site-wide: 9,991
  • In genetics: 394
• Year to date:
  • Site-wide: 1,899
• Since beginning of last month:
  • Site-wide: 4,629

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

• Downloaded 1,586 times
• Download rankings, all-time:
  • Site-wide: 19,262
  • In genetics: 780
• Year to date:
  • Site-wide: 79,483
• Since beginning of last month:
  • Site-wide: 56,406

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

• Downloaded 1,408 times
• Download rankings, all-time:
  • Site-wide: 23,362
  • In genomics: 2,039
• Year to date:
  • Site-wide: 19,230
• Since beginning of last month:
  • Site-wide: 26,792

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

• Downloaded 912 times
• Download rankings, all-time:
  • Site-wide: 45,976
  • In genomics: 3,480
• Year to date:
  • Site-wide: 119,103
• Since beginning of last month:
  • Site-wide: 90,116

Bidirectional Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of intermediate potential

• Downloaded 806 times
• Download rankings, all-time:
  • Site-wide: 55,508
  • In genetic and genomic medicine: 345
• Year to date:
  • Site-wide: 78,343
• Since beginning of last month:
  • Site-wide: 134,655

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

• Downloaded 768 times
• Download rankings, all-time:
  • Site-wide: 59,670
  • In genomics: 4,206
• Year to date:
  • Site-wide: 35,828
• Since beginning of last month:
  • Site-wide: 182,872

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

• Downloaded 702 times
• Download rankings, all-time:
  • Site-wide: 67,904
  • In genetics: 2,627
• Year to date:
  • Site-wide: 105,786
• Since beginning of last month:
  • Site-wide: 74,420

The circulating lipidome is largely defined by sex descriptors in the GOLDN, GeneBank and the ADNI studies

• Downloaded 616 times
• Download rankings, all-time:
  • Site-wide: 80,889
  • In biochemistry: 2,228
• Year to date:
  • Site-wide: 63,017
• Since beginning of last month:
  • Site-wide: 149,727

Genome-wide polygenic score with APOL1 risk genotypes predicts chronic kidney disease across major continental ancestries

• Downloaded 496 times
• Download rankings, all-time:
  • Site-wide: 105,143
  • In genetic and genomic medicine: 698
• Year to date:
  • Site-wide: 31,992
• Since beginning of last month:
  • Site-wide: 85,880

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

• Downloaded 494 times
• Download rankings, all-time:
  • Site-wide: 105,726
  • In genetic and genomic medicine: 688
• Year to date:
  • Site-wide: 153,646
• Since beginning of last month:
  • Site-wide: 95,517

HBA Copy Number and Kidney Disease Risk among Black Americans: a Longitudinal Cohort Study

• Downloaded 414 times
• Download rankings, all-time:
  • Site-wide: 126,063
  • In genetic and genomic medicine: 862
• Year to date:
  • Site-wide: 108,957
• Since beginning of last month:
  • Site-wide: 55,363

Leveraging a founder population to identify novel rare-population genetic determinants of lipidome

• Downloaded 390 times
• Download rankings, all-time:
  • Site-wide: 132,982
  • In genetics: 5,037
• Year to date:
  • Site-wide: 77,229
• Since beginning of last month:
  • Site-wide: 97,377