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Author: Feng Zhang

  • ORCiD: http://orcid.org/0000-0002-8708-4846
  • Most recently observed institution: Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, P. R. China

Rankings

  • All-time downloads: 157,197 (rank: 533 )
  • Categories:
    • biochemistry: 6,887 (rank: 305 )
    • bioengineering: 13,036 (rank: 48 )
    • bioinformatics: 2,139 (rank: 7,446 (tie) )
    • cancer biology: 726 (rank: 13,237 (tie) )
    • ecology: 442 (rank: 10,683 (tie) )
    • evolutionary biology: 786 (rank: 9,507 (tie) )
    • gastroenterology: 166 (rank: 1,712 (tie) )
    • genetics: 1,241 (rank: 14,027 (tie) )
    • genomics: 33,891 (rank: 322 )
    • immunology: 330 (rank: 25,792 (tie) )
    • infectious diseases: 1,015 (rank: 24,375 (tie) )
    • microbiology: 9,704 (rank: 1,553 )
    • molecular biology: 67,395 (rank: 1 )
    • neuroscience: 11,993 (rank: 1,053 (tie) )
    • plant biology: 1,476 (rank: 2,488 (tie) )
    • synthetic biology: 2,031 (rank: 760 (tie) )
    • systems biology: 3,939 (rank: 1,001 )

Downloads per author, site-wide

Preprints

Protocol: Genome-scale CRISPR-Cas9 Knockout and Transcriptional Activation Screening

molecular biology more details view paper
  • Downloaded 27,792 times
  • Download rankings, all-time:
    • Site-wide: 257
    • In molecular biology: 3
  • Year to date:
    • Site-wide: 1,851
  • Since beginning of last month:
    • Site-wide: 2,750

LAMP-Seq: Population-Scale COVID-19 Diagnostics Using Combinatorial Barcoding

molecular biology more details view paper
  • Downloaded 17,832 times
  • Download rankings, all-time:
    • Site-wide: 420
    • In molecular biology: 6
  • Year to date:
    • Site-wide: 1,265
  • Since beginning of last month:
    • Site-wide: 1,550

Improved vectors and genome-wide libraries for CRISPR screening

genomics more details view paper
  • Downloaded 11,182 times
  • Download rankings, all-time:
    • Site-wide: 787
    • In genomics: 54
  • Year to date:
    • Site-wide: 7,188
  • Since beginning of last month:
    • Site-wide: 10,271

DNA microscopy: Optics-free spatio-genetic imaging by a stand-alone chemical reaction

bioengineering more details view paper
  • Downloaded 9,330 times
  • Download rankings, all-time:
    • Site-wide: 995
    • In bioengineering: 7
  • Year to date:
    • Site-wide: 62,124
  • Since beginning of last month:
    • Site-wide: 53,016

Pooled optical screens in human cells

genomics more details view paper
  • Downloaded 9,174 times
  • Download rankings, all-time:
    • Site-wide: 1,021
    • In genomics: 77
  • Year to date:
    • Site-wide: 14,936
  • Since beginning of last month:
    • Site-wide: 39,066

DroNc-Seq: Deciphering cell types in human archived brain tissues by massively-parallel single nucleus RNA-seq

genomics more details view paper
  • Downloaded 7,051 times
  • Download rankings, all-time:
    • Site-wide: 1,429
    • In genomics: 120
  • Year to date:
    • Site-wide: 48,522
  • Since beginning of last month:
    • Site-wide: 33,495

In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with Autism risk genes

genomics more details view paper
  • Downloaded 6,484 times
  • Download rankings, all-time:
    • Site-wide: 1,593
    • In genomics: 131
  • Year to date:
    • Site-wide: 4,919
  • Since beginning of last month:
    • Site-wide: 15,472

CRISPR/Cas9-APEX-mediated proximity labeling enables discovery of proteins associated with a predefined genomic locus in living cells

biochemistry more details view paper
  • Downloaded 6,399 times
  • Download rankings, all-time:
    • Site-wide: 1,619
    • In biochemistry: 21
  • Year to date:
    • Site-wide: 42,436
  • Since beginning of last month:
    • Site-wide: 43,610

Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

microbiology more details view paper
  • Downloaded 6,044 times
  • Download rankings, all-time:
    • Site-wide: 1,767
    • In microbiology: 148
  • Year to date:
    • Site-wide: 21,363
  • Since beginning of last month:
    • Site-wide: 28,156

A cellular and spatial map of the choroid plexus across brain ventricles and ages

neuroscience more details view paper
  • Downloaded 5,323 times
  • Download rankings, all-time:
    • Site-wide: 2,093
    • In neuroscience: 114
  • Year to date:
    • Site-wide: 1,440
  • Since beginning of last month:
    • Site-wide: 2,879

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

molecular biology more details view paper
  • Downloaded 4,780 times
  • Download rankings, all-time:
    • Site-wide: 2,433
    • In molecular biology: 47
  • Year to date:
    • Site-wide: 85,230
  • Since beginning of last month:
    • Site-wide: 85,347

Multiplex gene editing by CRISPR-Cpf1 through autonomous processing of a single crRNA array

molecular biology more details view paper
  • Downloaded 4,758 times
  • Download rankings, all-time:
    • Site-wide: 2,451
    • In molecular biology: 49
  • Year to date:
    • Site-wide: 69,780
  • Since beginning of last month:
    • Site-wide: 110,701

High-resolution interrogation of functional elements in the noncoding genome

molecular biology more details view paper
  • Downloaded 4,051 times
  • Download rankings, all-time:
    • Site-wide: 3,076
    • In molecular biology: 66
  • Year to date:
    • Site-wide: 85,635
  • Since beginning of last month:
    • Site-wide: 103,536

Div-Seq: A single nucleus RNA-Seq method reveals dynamics of rare adult newborn neurons in the CNS

neuroscience more details view paper
  • Downloaded 3,781 times
  • Download rankings, all-time:
    • Site-wide: 3,415
    • In neuroscience: 252
  • Year to date:
    • Site-wide: 59,337
  • Since beginning of last month:
    • Site-wide: 94,378

Genome Editing With Targeted Deaminases

bioengineering more details view paper
  • Downloaded 3,706 times
  • Download rankings, all-time:
    • Site-wide: 3,503
    • In bioengineering: 38
  • Year to date:
    • Site-wide: 72,228
  • Since beginning of last month:
    • Site-wide: 49,930

A Survey of Genome Editing Activity for 16 Cpf1 orthologs

molecular biology more details view paper
  • Downloaded 3,135 times
  • Download rankings, all-time:
    • Site-wide: 4,437
    • In molecular biology: 97
  • Year to date:
    • Site-wide: 46,187
  • Since beginning of last month:
    • Site-wide: 44,008

Integrated design, execution, and analysis of arrayed and pooled CRISPR genome editing experiments

molecular biology more details view paper
  • Downloaded 3,007 times
  • Download rankings, all-time:
    • Site-wide: 4,692
    • In molecular biology: 103
  • Year to date:
    • Site-wide: 42,387
  • Since beginning of last month:
    • Site-wide: 61,875

Ongoing Global and Regional Adaptive Evolution of SARS-CoV-2

microbiology more details view paper
  • Downloaded 2,096 times
  • Download rankings, all-time:
    • Site-wide: 7,939
    • In microbiology: 465
  • Year to date:
    • Site-wide: 1,758
  • Since beginning of last month:
    • Site-wide: 8,495

Engineered Cpf1 Enzymes with Altered PAM Specificities

synthetic biology more details view paper
  • Downloaded 2,031 times
  • Download rankings, all-time:
    • Site-wide: 8,294
    • In synthetic biology: 84
  • Year to date:
    • Site-wide: 99,137
  • Since beginning of last month:
    • Site-wide: 72,135

BLISS: quantitative and versatile genome-wide profiling of DNA breaks in situ

molecular biology more details view paper
  • Downloaded 1,650 times
  • Download rankings, all-time:
    • Site-wide: 11,337
    • In molecular biology: 302
  • Year to date:
    • Site-wide: 85,648
  • Since beginning of last month:
    • Site-wide: 78,192

Direct in vivo mapping of functional suppressors in glioblastoma genome

systems biology more details view paper
  • Downloaded 1,628 times
  • Download rankings, all-time:
    • Site-wide: 11,569
    • In systems biology: 207
  • Year to date:
    • Site-wide: 49,187
  • Since beginning of last month:
    • Site-wide: 30,495

The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

bioinformatics more details view paper
  • Downloaded 1,583 times
  • Download rankings, all-time:
    • Site-wide: 12,017
    • In bioinformatics: 1,406
  • Year to date:
    • Site-wide: 44,549
  • Since beginning of last month:
    • Site-wide: 80,969

Cas13b is a Type VI-B CRISPR-associated RNA-Guided RNase differentially regulated by accessory proteins Csx27 and Csx28

microbiology more details view paper
  • Downloaded 1,564 times
  • Download rankings, all-time:
    • Site-wide: 12,227
    • In microbiology: 708
  • Year to date:
    • Site-wide: 122,094
  • Since beginning of last month:
    • Site-wide: 112,504

Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism

neuroscience more details view paper
  • Downloaded 1,481 times
  • Download rankings, all-time:
    • Site-wide: 13,252
    • In neuroscience: 1,459
  • Year to date:
    • Site-wide: 14,275
  • Since beginning of last month:
    • Site-wide: 32,234

Pooled AAV-CRISPR Screen with Targeted Amplicon Sequencing

systems biology more details view paper
  • Downloaded 1,426 times
  • Download rankings, all-time:
    • Site-wide: 14,036
    • In systems biology: 255
  • Year to date:
    • Site-wide: 62,894
  • Since beginning of last month:
    • Site-wide: 43,445

GUIDES: sgRNA design for loss-of-function screens

genetics more details view paper
  • Downloaded 1,241 times
  • Download rankings, all-time:
    • Site-wide: 17,310
    • In genetics: 819
  • Year to date:
    • Site-wide: 99,579
  • Since beginning of last month:
    • Site-wide: 65,950

Multi-cellular communities are perturbed in the aging human brain and with Alzheimer's disease

neuroscience more details view paper
  • Downloaded 1,046 times
  • Download rankings, all-time:
    • Site-wide: 22,281
    • In neuroscience: 2,776
  • Year to date:
    • Site-wide: 3,135
  • Since beginning of last month:
    • Site-wide: 12,056

Assessing the impact of a symptom-based mass screening and testing intervention during a novel infectious disease outbreak: The case of COVID-19

infectious diseases more details view paper
  • Downloaded 1,015 times
  • Download rankings, all-time:
    • Site-wide: 23,249
    • In infectious diseases: 1,986
  • Year to date:
    • Site-wide: 64,927
  • Since beginning of last month:
    • Site-wide: 58,793

Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics

systems biology more details view paper
  • Downloaded 885 times
  • Download rankings, all-time:
    • Site-wide: 28,351
    • In systems biology: 584
  • Year to date:
    • Site-wide: 8,606
  • Since beginning of last month:
    • Site-wide: 13,798

Optimization of multiplexed CRISPR/Cas9 system for highly efficient genome editing in Setaria viridis

plant biology more details view paper
  • Downloaded 816 times
  • Download rankings, all-time:
    • Site-wide: 31,700
    • In plant biology: 576
  • Year to date:
    • Site-wide: 23,850
  • Since beginning of last month:
    • Site-wide: 18,392

The evolution of red colour vision is linked to coordinated rhodopsin tuning in lycaenid butterflies

evolutionary biology more details view paper
  • Downloaded 786 times
  • Download rankings, all-time:
    • Site-wide: 33,389
    • In evolutionary biology: 1,552
  • Year to date:
    • Site-wide: 26,096
  • Since beginning of last month:
    • Site-wide: 27,203

Essentiality of CREBBP in EP300 truncated B-cell lymphoma revealed by genome-wide CRISPR-Cas9 screen

cancer biology more details view paper
  • Downloaded 726 times
  • Download rankings, all-time:
    • Site-wide: 37,307
    • In cancer biology: 1,004
  • Year to date:
    • Site-wide: 32,855
  • Since beginning of last month:
    • Site-wide: 49,815

An R Implementation of Tumor-Stroma-Immune Transcriptome Deconvolution Pipeline using DeMixT

bioinformatics more details view paper
  • Downloaded 556 times
  • Download rankings, all-time:
    • Site-wide: 52,453
    • In bioinformatics: 5,342
  • Year to date:
    • Site-wide: 93,777
  • Since beginning of last month:
    • Site-wide: 96,544

A Genetically Encoded Trimethylsilyl 1D 1H-NMR Probe for Conformation Change in Large Membrane Protein Complexes

biochemistry more details view paper
  • Downloaded 488 times
  • Download rankings, all-time:
    • Site-wide: 61,077
    • In biochemistry: 1,614
  • Year to date:
    • Site-wide: 81,496
  • Since beginning of last month:
    • Site-wide: 59,265

PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana

plant biology more details view paper
  • Downloaded 460 times
  • Download rankings, all-time:
    • Site-wide: 65,063
    • In plant biology: 1,641
  • Year to date:
    • Site-wide: 128,054
  • Since beginning of last month:
    • Site-wide: 141,453

Movement behavioral plasticity of benthic diatoms driven by optimal foraging

ecology more details view paper
  • Downloaded 442 times
  • Download rankings, all-time:
    • Site-wide: 67,905
    • In ecology: 1,830
  • Year to date:
    • Site-wide: 81,193
  • Since beginning of last month:
    • Site-wide: 78,984

Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity

neuroscience more details view paper
  • Downloaded 362 times
  • Download rankings, all-time:
    • Site-wide: 82,060
    • In neuroscience: 12,349
  • Year to date:
    • Site-wide: 109,417
  • Since beginning of last month:
    • Site-wide: 138,783

Regulatory B cells contribute to the alleviation of colitis induced by Dextran Sulphate Sodium after H.pylori infection

immunology more details view paper
  • Downloaded 330 times
  • Download rankings, all-time:
    • Site-wide: 88,551
    • In immunology: 2,594
  • Year to date:
    • Site-wide: 105,067
  • Since beginning of last month:
    • Site-wide: 125,557

Effect of recombinant phycocyanin on photosynthetic system in Chlamydomonas reinhardtii

molecular biology more details view paper
  • Downloaded 247 times
  • Download rankings, all-time:
    • Site-wide: 107,594
    • In molecular biology: 3,188
  • Year to date:
    • Site-wide: 84,626
  • Since beginning of last month:
    • Site-wide: 82,329

Photosynthetic resistance and resilience under drought and rewatering in maize plants

plant biology more details view paper
  • Downloaded 200 times
  • Download rankings, all-time:
    • Site-wide: 119,094
    • In plant biology: 3,302
  • Year to date:
    • Site-wide: 66,990
  • Since beginning of last month:
    • Site-wide: 36,012

Evaluating the clinical performance of a novel dual-target stool DNA test for colorectal cancer detection

gastroenterology more details view paper
  • Downloaded 166 times
  • Download rankings, all-time:
    • Site-wide: 127,001
    • In gastroenterology: 174
  • Year to date:
    • Site-wide: 33,123
  • Since beginning of last month:
    • Site-wide: 60,271

Regulating AMPK and insulin level by Vinegar, Swimming and Refeeding on High-Fat Diet Rats to Rebuild Lipid Homeostasis

molecular biology more details view paper
  • Downloaded 143 times
  • Download rankings, all-time:
    • Site-wide: 132,241
    • In molecular biology: 3,934
  • Year to date:
    • Site-wide: 142,449
  • Since beginning of last month:
    • Site-wide: 145,608

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