Author: Feng Zhang

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Preprints

Protocol: Genome-scale CRISPR-Cas9 Knockout and Transcriptional Activation Screening

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LAMP-Seq: Population-Scale COVID-19 Diagnostics Using Combinatorial Barcoding

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Improved vectors and genome-wide libraries for CRISPR screening

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DNA microscopy: Optics-free spatio-genetic imaging by a stand-alone chemical reaction

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Pooled optical screens in human cells

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DroNc-Seq: Deciphering cell types in human archived brain tissues by massively-parallel single nucleus RNA-seq

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CRISPR/Cas9-APEX-mediated proximity labeling enables discovery of proteins associated with a predefined genomic locus in living cells

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Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

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In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with Autism risk genes

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C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

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Multiplex gene editing by CRISPR-Cpf1 through autonomous processing of a single crRNA array

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High-resolution interrogation of functional elements in the noncoding genome

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Div-Seq: A single nucleus RNA-Seq method reveals dynamics of rare adult newborn neurons in the CNS

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Genome Editing With Targeted Deaminases

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A cellular and spatial map of the choroid plexus across brain ventricles and ages

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A Survey of Genome Editing Activity for 16 Cpf1 orthologs

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Integrated design, execution, and analysis of arrayed and pooled CRISPR genome editing experiments

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Engineered Cpf1 Enzymes with Altered PAM Specificities

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BLISS: quantitative and versatile genome-wide profiling of DNA breaks in situ

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Cas13b is a Type VI-B CRISPR-associated RNA-Guided RNase differentially regulated by accessory proteins Csx27 and Csx28

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Direct in vivo mapping of functional suppressors in glioblastoma genome

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The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

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Pooled AAV-CRISPR Screen with Targeted Amplicon Sequencing

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GUIDES: sgRNA design for loss-of-function screens

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Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism

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Assessing the impact of a symptom-based mass screening and testing intervention during a novel infectious disease outbreak: The case of COVID-19

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Optimization of multiplexed CRISPR/Cas9 system for highly efficient genome editing in Setaria viridis

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The evolution of red colour vision is linked to coordinated rhodopsin tuning in lycaenid butterflies

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Essentiality of CREBBP in EP300 truncated B-cell lymphoma revealed by genome-wide CRISPR-Cas9 screen

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Ongoing Global and Regional Adaptive Evolution of SARS-CoV-2

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An R Implementation of Tumor-Stroma-Immune Transcriptome Deconvolution Pipeline using DeMixT

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PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana

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A Genetically Encoded Trimethylsilyl 1D 1H-NMR Probe for Conformation Change in Large Membrane Protein Complexes

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Movement behavioral plasticity of benthic diatoms driven by optimal foraging

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Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity

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Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics

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Regulatory B cells contribute to the alleviation of colitis induced by Dextran Sulphate Sodium after H.pylori infection

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Effect of recombinant phycocyanin on photosynthetic system in Chlamydomonas reinhardtii

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Regulating AMPK and insulin level by Vinegar, Swimming and Refeeding on High-Fat Diet Rats to Rebuild Lipid Homeostasis

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Photosynthetic resistance and resilience under drought and rewatering in maize plants

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